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Murcko scaffold

2-(Pyrrolidin-3-yl)-1,3-thiazole scaffold

99 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
99
With full pages
3
Scaffold SMILES

c1csc(C2CCNC2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Pyrrolidin-3-yl)-1,3-thiazole page
Murcko scaffold c1csc(C2CCNC2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 99 chemicals

4-Methyl-2-(pyrrolidin-3-yl)-1,3-thiazole chemical structure, C8H12N2S, CAS 1257521-56-4
4-Methyl-2-(pyrrolidin-3-yl)-1,3-thiazole
CAS 1257521-56-4C8H12N2S
4-Bromo-2-(pyrrolidin-3-yl)thiazole chemical structure, C7H9BrN2S, CAS 1159815-45-8
4-Bromo-2-(pyrrolidin-3-yl)thiazole
CAS 1159815-45-8C7H9BrN2S
4-Amino-2-(pyrrolidin-3-yl)thiazole chemical structure, C7H11N3S, CAS 1159821-10-9
4-Amino-2-(pyrrolidin-3-yl)thiazole
CAS 1159821-10-9C7H11N3S
5-Bromo-2-(pyrrolidin-3-yl)thiazole chemical structure, C7H9BrN2S, CAS 1159821-16-5
5-Bromo-2-(pyrrolidin-3-yl)thiazole
CAS 1159821-16-5C7H9BrN2S
2-(Pyrrolidin-3-yl)-1,3-thiazole chemical structure, C7H10N2S, CAS 630121-89-0
2-(Pyrrolidin-3-yl)-1,3-thiazole
CAS 630121-89-0C7H10N2S
3-(4-Chloromethyl-thiazol-2-yl)-pyrrolidine-1-carboxylic acid tert-butyl ester chemical structure, C13H19ClN2O2S, CAS 1044138-11-5
3-(4-Chloromethyl-thiazol-2-yl)-pyrrolidine-1-carboxylic acid tert-butyl ester
CAS 1044138-11-5C13H19ClN2O2S
4-(1,3-Thiazol-2-yl)pyrrolidin-3-amine chemical structure, C7H11N3S, CAS 1186299-86-4
4-(1,3-Thiazol-2-yl)pyrrolidin-3-amine
CAS 1186299-86-4C7H11N3S
2-(Pyrrolidin-3-yl)thiazole hydrochloride chemical structure, C7H11ClN2S, CAS 1239205-70-9
2-(Pyrrolidin-3-yl)thiazole hydrochloride
CAS 1239205-70-9C7H11ClN2S
4,5-Dimethyl-2-(pyrrolidin-3-yl)-1,3-thiazole chemical structure, C9H14N2S, CAS 1369154-60-8
4,5-Dimethyl-2-(pyrrolidin-3-yl)-1,3-thiazole
CAS 1369154-60-8C9H14N2S
5-Methyl-2-(pyrrolidin-3-yl)thiazole chemical structure, C8H12N2S, CAS 1368177-03-0
5-Methyl-2-(pyrrolidin-3-yl)thiazole
CAS 1368177-03-0C8H12N2S
2-(Pyrrolidin-3-yl)-1,3-thiazole-4-carboxylic acid chemical structure, C8H10N2O2S, CAS 1507719-72-3
2-(Pyrrolidin-3-yl)-1,3-thiazole-4-carboxylic acid
CAS 1507719-72-3C8H10N2O2S
2-[2-(Pyrrolidin-3-yl)-1,3-thiazol-4-yl]acetic acid chemical structure, C9H12N2O2S, CAS 1533008-04-6
2-[2-(Pyrrolidin-3-yl)-1,3-thiazol-4-yl]acetic acid
CAS 1533008-04-6C9H12N2O2S
Methyl 2-(pyrrolidin-3-yl)-1,3-thiazole-4-carboxylate chemical structure, C9H12N2O2S, CAS 1558372-74-9
Methyl 2-(pyrrolidin-3-yl)-1,3-thiazole-4-carboxylate
CAS 1558372-74-9C9H12N2O2S
Ethyl 2-(pyrrolidin-3-yl)-1,3-thiazole-4-carboxylate chemical structure, C10H14N2O2S, CAS 1211517-28-0
Ethyl 2-(pyrrolidin-3-yl)-1,3-thiazole-4-carboxylate
CAS 1211517-28-0C10H14N2O2S
2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)thiazole-5-carboxylic acid chemical structure, C13H18N2O4S, CAS 1211586-67-2
2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)thiazole-5-carboxylic acid
CAS 1211586-67-2C13H18N2O4S
4-Ethyl-2-(pyrrolidin-3-yl)-1,3-thiazole chemical structure, C9H14N2S, CAS 1784891-96-8
4-Ethyl-2-(pyrrolidin-3-yl)-1,3-thiazole
CAS 1784891-96-8C9H14N2S
4-(Propan-2-yl)-2-(pyrrolidin-3-yl)-1,3-thiazole chemical structure, C10H16N2S, CAS 1779942-52-7
4-(Propan-2-yl)-2-(pyrrolidin-3-yl)-1,3-thiazole
CAS 1779942-52-7C10H16N2S
2-(Pyrrolidin-3-yl)-1,3-thiazole-5-carboxylic acid chemical structure, C8H10N2O2S, CAS 1780625-07-1
2-(Pyrrolidin-3-yl)-1,3-thiazole-5-carboxylic acid
CAS 1780625-07-1C8H10N2O2S
Methyl 2-(pyrrolidin-3-yl)-1,3-thiazole-5-carboxylate chemical structure, C9H12N2O2S, CAS 1780965-89-0
Methyl 2-(pyrrolidin-3-yl)-1,3-thiazole-5-carboxylate
CAS 1780965-89-0C9H12N2O2S
2-(Pyrrolidin-3-yl)-4-(trifluoromethyl)thiazole chemical structure, C8H9F3N2S, CAS 1781060-08-9
2-(Pyrrolidin-3-yl)-4-(trifluoromethyl)thiazole
CAS 1781060-08-9C8H9F3N2S
2-(Pyrrolidin-3-yl)thiazole-4-carbaldehyde chemical structure, C8H10N2OS, CAS 1888856-49-2
2-(Pyrrolidin-3-yl)thiazole-4-carbaldehyde
CAS 1888856-49-2C8H10N2OS
5-Chloro-2-(pyrrolidin-3-yl)thiazole chemical structure, C7H9ClN2S, CAS 1891068-02-2
5-Chloro-2-(pyrrolidin-3-yl)thiazole
CAS 1891068-02-2C7H9ClN2S
2-(Pyrrolidin-3-yl)thiazole dihydrochloride chemical structure, C7H12Cl2N2S, CAS 1820618-32-3
2-(Pyrrolidin-3-yl)thiazole dihydrochloride
CAS 1820618-32-3C7H12Cl2N2S
4-Methyl-2-(pyrrolidin-3-yl)thiazole-5-carboxylic acid chemical structure, C9H12N2O2S, CAS 2098081-26-4
4-Methyl-2-(pyrrolidin-3-yl)thiazole-5-carboxylic acid
CAS 2098081-26-4C9H12N2O2S