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Murcko scaffold

Ring system with 3 rings and 16 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
7
With full pages
3
Scaffold SMILES

c1coc(-c2ncc(N3CCNCC3)o2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1coc(-c2ncc(N3CCNCC3)o2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

5-(4-Ethylpiperazin-1-yl)-2-(furan-2-yl)-1,3-oxazole-4-carbonitrile chemical structure, C14H16N4O2, CAS 844824-48-2
5-(4-Ethylpiperazin-1-yl)-2-(furan-2-yl)-1,3-oxazole-4-carbonitrile
CAS 844824-48-2C14H16N4O2
5-[4-(2-Chloroacetyl)piperazin-1-yl]-2-(furan-2-yl)-1,3-oxazole-4-carbonitrile chemical structure, C14H13ClN4O3, CAS 1031130-76-3
5-[4-(2-Chloroacetyl)piperazin-1-yl]-2-(furan-2-yl)-1,3-oxazole-4-carbonitrile
CAS 1031130-76-3C14H13ClN4O3
2-(Furan-2-yl)-5-(piperazin-1-yl)-1,3-oxazole-4-carbonitrile chemical structure, C12H12N4O2, CAS 1000932-90-0
2-(Furan-2-yl)-5-(piperazin-1-yl)-1,3-oxazole-4-carbonitrile
CAS 1000932-90-0C12H12N4O2
2-(Furan-2-yl)-5-[4-(prop-2-yn-1-yl)piperazin-1-yl]-1,3-oxazole-4-carbonitrile chemical structure, C15H14N4O2, CAS 1281080-34-9
2-(Furan-2-yl)-5-[4-(prop-2-yn-1-yl)piperazin-1-yl]-1,3-oxazole-4-carbonitrile
CAS 1281080-34-9C15H14N4O2
2-(Furan-2-yl)-5-[4-(prop-2-enoyl)piperazin-1-yl]-1,3-oxazole-4-carbonitrile chemical structure, C15H14N4O3, CAS 2094196-98-0
2-(Furan-2-yl)-5-[4-(prop-2-enoyl)piperazin-1-yl]-1,3-oxazole-4-carbonitrile
CAS 2094196-98-0C15H14N4O3
5-[4-(2-Chloropropanoyl)piperazin-1-yl]-2-(furan-2-yl)-1,3-oxazole-4-carbonitrile chemical structure, C15H15ClN4O3, CAS 2411274-68-3
5-[4-(2-Chloropropanoyl)piperazin-1-yl]-2-(furan-2-yl)-1,3-oxazole-4-carbonitrile
CAS 2411274-68-3C15H15ClN4O3
tert-Butyl 4-[4-cyano-2-(furan-2-yl)-1,3-oxazol-5-yl]piperazine-1-carboxylate chemical structure, C17H20N4O4, CAS 2680863-05-0
tert-Butyl 4-[4-cyano-2-(furan-2-yl)-1,3-oxazol-5-yl]piperazine-1-carboxylate
CAS 2680863-05-0C17H20N4O4