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Murcko scaffold

4-Phenyl-2-(1H-pyrazol-1-yl)-1,3-thiazole scaffold

148 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
148
With full pages
16
Scaffold SMILES

c1ccc(-c2csc(-n3cccn3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Phenyl-2-(1H-pyrazol-1-yl)-1,3-thiazole page
Murcko scaffold c1ccc(-c2csc(-n3cccn3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 148 chemicals

4-(4-Bromophenyl)-2-(3,4,5-trimethylpyrazol-1-yl)-1,3-thiazole chemical structure, C15H14BrN3S, CAS 82100-82-1
4-(4-Bromophenyl)-2-(3,4,5-trimethylpyrazol-1-yl)-1,3-thiazole
CAS 82100-82-1C15H14BrN3S
4-Phenyl-2-(3,4,5-trimethyl-1H-pyrazol-1-yl)-1,3-thiazole chemical structure, C15H15N3S, CAS 82100-73-0
4-Phenyl-2-(3,4,5-trimethyl-1H-pyrazol-1-yl)-1,3-thiazole
CAS 82100-73-0C15H15N3S
Thiazole, 2-(3,5-dimethyl-1-pyrazolyl)-4-phenyl- chemical structure, C14H13N3S, CAS 75007-33-9
Thiazole, 2-(3,5-dimethyl-1-pyrazolyl)-4-phenyl-
CAS 75007-33-9C14H13N3S
4-(4-Bromophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-1,3-thiazole chemical structure, C14H12BrN3S, CAS 82100-81-0
4-(4-Bromophenyl)-2-(3,5-dimethyl-1H-pyrazol-1-yl)-1,3-thiazole
CAS 82100-81-0C14H12BrN3S
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-4-(4-fluorophenyl)-1,3-thiazole chemical structure, C14H12FN3S, CAS 82100-75-2
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-4-(4-fluorophenyl)-1,3-thiazole
CAS 82100-75-2C14H12FN3S
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-4-(4-methoxyphenyl)-1,3-thiazole chemical structure, C15H15N3OS, CAS 385796-45-2
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-4-(4-methoxyphenyl)-1,3-thiazole
CAS 385796-45-2C15H15N3OS
2-(3,5-Dimethylpyrazol-1-yl)-4-(4-iodophenyl)-1,3-thiazole chemical structure, C14H12IN3S, CAS 400742-02-1
2-(3,5-Dimethylpyrazol-1-yl)-4-(4-iodophenyl)-1,3-thiazole
CAS 400742-02-1C14H12IN3S
Ethyl 1-[4-(3-fluorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate chemical structure, C16H11F4N3O2S, CAS 385416-11-5
Ethyl 1-[4-(3-fluorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate
CAS 385416-11-5C16H11F4N3O2S
1-[4-(3-Fluorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid chemical structure, C14H7F4N3O2S, CAS 385416-14-8
1-[4-(3-Fluorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid
CAS 385416-14-8C14H7F4N3O2S
2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-(3-nitrophenyl)-1,3-thiazole chemical structure, C14H9F3N4O2S, CAS 955964-27-9
2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-(3-nitrophenyl)-1,3-thiazole
CAS 955964-27-9C14H9F3N4O2S
Methyl 2-{2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-phenyl-1,3-thiazol-5-yl}acetate chemical structure, C17H14F3N3O2S, CAS 955962-94-4
Methyl 2-{2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-phenyl-1,3-thiazol-5-yl}acetate
CAS 955962-94-4C17H14F3N3O2S
2-{2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-phenyl-1,3-thiazol-5-yl}acetic acid chemical structure, C16H12F3N3O2S, CAS 955976-94-0
2-{2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-phenyl-1,3-thiazol-5-yl}acetic acid
CAS 955976-94-0C16H12F3N3O2S
2-{2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-phenyl-1,3-thiazol-5-yl}acetohydrazide chemical structure, C16H14F3N5OS, CAS 955976-95-1
2-{2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-phenyl-1,3-thiazol-5-yl}acetohydrazide
CAS 955976-95-1C16H14F3N5OS
Ethyl 1-[4-(2-fluorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate chemical structure, C16H11F4N3O2S, CAS 955966-72-0
Ethyl 1-[4-(2-fluorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate
CAS 955966-72-0C16H11F4N3O2S
1-[4-(2-Fluorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid chemical structure, C14H7F4N3O2S, CAS 955975-49-2
1-[4-(2-Fluorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid
CAS 955975-49-2C14H7F4N3O2S
Methyl 4-[2-(3,4,5-trimethyl-1H-pyrazol-1-yl)-1,3-thiazol-4-yl]phenyl ether chemical structure, C16H17N3OS, CAS 955961-66-7
Methyl 4-[2-(3,4,5-trimethyl-1H-pyrazol-1-yl)-1,3-thiazol-4-yl]phenyl ether
CAS 955961-66-7C16H17N3OS
4-Phenyl-2-(1H-pyrazol-1-yl)-1,3-thiazole chemical structure, C12H9N3S, CAS 128432-98-4
4-Phenyl-2-(1H-pyrazol-1-yl)-1,3-thiazole
CAS 128432-98-4C12H9N3S
Methyl 4-[2-(1H-pyrazol-1-yl)-1,3-thiazol-4-yl]phenyl ether chemical structure, C13H11N3OS, CAS 128433-02-3
Methyl 4-[2-(1H-pyrazol-1-yl)-1,3-thiazol-4-yl]phenyl ether
CAS 128433-02-3C13H11N3OS
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-4-[3-(trifluoromethyl)phenyl]-1,3-thiazole chemical structure, C15H12F3N3S, CAS 955961-89-4
2-(3,5-Dimethyl-1H-pyrazol-1-yl)-4-[3-(trifluoromethyl)phenyl]-1,3-thiazole
CAS 955961-89-4C15H12F3N3S
Ethyl 1-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate chemical structure, C16H10Cl2F3N3O2S, CAS 956961-73-2
Ethyl 1-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate
CAS 956961-73-2C16H10Cl2F3N3O2S
1-[4-(3,4-Dichlorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid chemical structure, C14H6Cl2F3N3O2S, CAS 955976-66-6
1-[4-(3,4-Dichlorophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid
CAS 955976-66-6C14H6Cl2F3N3O2S
Ethyl 1-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate chemical structure, C16H11F3N4O4S, CAS 159885-64-0
Ethyl 1-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate
CAS 159885-64-0C16H11F3N4O4S
Ethyl 1-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate chemical structure, C17H14F3N3O2S, CAS 159885-65-1
Ethyl 1-[4-(4-methylphenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate
CAS 159885-65-1C17H14F3N3O2S
Ethyl 1-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate chemical structure, C16H11F3N4O4S, CAS 955975-70-9
Ethyl 1-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate
CAS 955975-70-9C16H11F3N4O4S