CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 21 atoms

38 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
38
With full pages
9
Scaffold SMILES

O=C(NCc1cc2ccccc2[nH]c1=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1cc2ccccc2[nH]c1=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 38 of 38 chemicals

RefChem:380560 chemical structure, C21H22N2O3, CAS 5272-63-9
RefChem:380560
CAS 5272-63-9C21H22N2O3
N-(2-Methoxyethyl)-N-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]benzamide chemical structure, C21H22N2O3, CAS 838891-08-0
N-(2-Methoxyethyl)-N-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]benzamide
CAS 838891-08-0C21H22N2O3
N-Methyl-N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]benzamide chemical structure, C19H18N2O2, CAS 671763-84-1
N-Methyl-N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]benzamide
CAS 671763-84-1C19H18N2O2
3-Chloro-N-[(2-hydroxy-6-methylquinolin-3-yl)methyl]-N-methylbenzamide chemical structure, C19H17ClN2O2, CAS 713504-04-2
3-Chloro-N-[(2-hydroxy-6-methylquinolin-3-yl)methyl]-N-methylbenzamide
CAS 713504-04-2C19H17ClN2O2
N-Methyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide chemical structure, C18H16N2O2, CAS 674817-25-5
N-Methyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide
CAS 674817-25-5C18H16N2O2
N,3-dimethyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide chemical structure, C19H18N2O2, CAS 714923-90-7
N,3-dimethyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide
CAS 714923-90-7C19H18N2O2
N-tert-Butyl-2-methyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide chemical structure, C22H24N2O2, CAS 714253-02-8
N-tert-Butyl-2-methyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide
CAS 714253-02-8C22H24N2O2
N,4-dimethyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide chemical structure, C19H18N2O2, CAS 672343-83-8
N,4-dimethyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide
CAS 672343-83-8C19H18N2O2
N-Methyl-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]benzamide chemical structure, C19H18N2O2, CAS 672272-91-2
N-Methyl-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]benzamide
CAS 672272-91-2C19H18N2O2
N-Ethyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide chemical structure, C19H18N2O2, CAS 674354-23-5
N-Ethyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide
CAS 674354-23-5C19H18N2O2
N,2-dimethyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide chemical structure, C19H18N2O2, CAS 714240-76-3
N,2-dimethyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide
CAS 714240-76-3C19H18N2O2
2-Fluoro-N-methyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide chemical structure, C18H15FN2O2, CAS 672341-68-3
2-Fluoro-N-methyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide
CAS 672341-68-3C18H15FN2O2
3-Chloro-N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-methylbenzamide chemical structure, C19H17ClN2O3, CAS 717894-45-6
3-Chloro-N-[(6-methoxy-2-oxo-1H-quinolin-3-yl)methyl]-N-methylbenzamide
CAS 717894-45-6C19H17ClN2O3
4-Fluoro-N-methyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide chemical structure, C18H15FN2O2, CAS 673455-33-9
4-Fluoro-N-methyl-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide
CAS 673455-33-9C18H15FN2O2
3,4,5-Trimethoxy-N-methyl-N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]benzamide chemical structure, C22H24N2O5, CAS 1396980-07-6
3,4,5-Trimethoxy-N-methyl-N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]benzamide
CAS 1396980-07-6C22H24N2O5
N-Ethyl-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]-3-nitrobenzamide chemical structure, C20H19N3O4, CAS 673445-72-2
N-Ethyl-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]-3-nitrobenzamide
CAS 673445-72-2C20H19N3O4
RefChem:382259 chemical structure, C19H17N3O4, CAS 5730-01-8
RefChem:382259
CAS 5730-01-8C19H17N3O4
RefChem:313964 chemical structure, C20H19N3O4, CAS 5752-39-6
RefChem:313964
CAS 5752-39-6C20H19N3O4
N-tert-Butyl-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]-3-nitrobenzamide chemical structure, C22H23N3O4, CAS 714245-23-5
N-tert-Butyl-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]-3-nitrobenzamide
CAS 714245-23-5C22H23N3O4
N-[(6-Methyl-2-oxo-1H-quinolin-3-yl)methyl]-3-nitro-N-propan-2-ylbenzamide chemical structure, C21H21N3O4, CAS 714253-11-9
N-[(6-Methyl-2-oxo-1H-quinolin-3-yl)methyl]-3-nitro-N-propan-2-ylbenzamide
CAS 714253-11-9C21H21N3O4
3-Chloro-N-methyl-N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]benzamide chemical structure, C19H17ClN2O2, CAS 876721-39-0
3-Chloro-N-methyl-N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]benzamide
CAS 876721-39-0C19H17ClN2O2
N-((2-Hydroxy-7-methylquinolin-3-yl)methyl)-4-methoxy-N-(2-methoxyethyl)benzamide chemical structure, C22H24N2O4, CAS 838875-94-8
N-((2-Hydroxy-7-methylquinolin-3-yl)methyl)-4-methoxy-N-(2-methoxyethyl)benzamide
CAS 838875-94-8C22H24N2O4
4-Chloro-N-(2-methoxyethyl)-N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]benzamide chemical structure, C21H21ClN2O3, CAS 838899-51-7
4-Chloro-N-(2-methoxyethyl)-N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]benzamide
CAS 838899-51-7C21H21ClN2O3
N-(2-Methylpropyl)-3-nitro-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide chemical structure, C21H21N3O4, CAS 838874-41-2
N-(2-Methylpropyl)-3-nitro-N-[(2-oxo-1H-quinolin-3-yl)methyl]benzamide
CAS 838874-41-2C21H21N3O4