Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

6-(Benzylthio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one scaffold

28 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 18
Chemicals: 28
With full pages: 10

Scaffold SMILES

O=c1[nH]c(SCc2ccccc2)nc2[nH]ncc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 6-(Benzylthio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one page

Murcko scaffold O=c1[nH]c(SCc2ccccc2)nc2[nH]ncc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

6-((4-Nitrobenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C12H9N5O3S, CAS 877630-37-0

6-((4-Nitrobenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 877630-37-0C₁₂H₉N₅O₃S

6-((3-Nitrobenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C12H9N5O3S, CAS 877630-47-2

6-((3-Nitrobenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 877630-47-2C₁₂H₉N₅O₃S

6-[(2-Chlorophenyl)methylsulfanyl]-1,2-dihydropyrazolo[3,4-d]pyrimidin-4-one chemical structure, C12H9ClN4OS, CAS 877630-74-5

6-[(2-Chlorophenyl)methylsulfanyl]-1,2-dihydropyrazolo[3,4-d]pyrimidin-4-one

CAS 877630-74-5C₁₂H₉ClN₄OS

6-((4-Methylbenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C13H12N4OS, CAS 877630-40-5

6-((4-Methylbenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 877630-40-5C₁₃H₁₂N₄OS

6-((2,5-Dimethylbenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C14H14N4OS, CAS 877630-39-2

6-((2,5-Dimethylbenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 877630-39-2C₁₄H₁₄N₄OS

6-[(2-Methylphenyl)methylsulfanyl]-1,2-dihydropyrazolo[3,4-d]pyrimidin-4-one chemical structure, C13H12N4OS, CAS 877630-36-9

6-[(2-Methylphenyl)methylsulfanyl]-1,2-dihydropyrazolo[3,4-d]pyrimidin-4-one

CAS 877630-36-9C₁₃H₁₂N₄OS

6-((3-Methylbenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C13H12N4OS, CAS 877630-38-1

6-((3-Methylbenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 877630-38-1C₁₃H₁₂N₄OS

6-((3-Chlorobenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C12H9ClN4OS, CAS 877630-76-7

6-((3-Chlorobenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 877630-76-7C₁₂H₉ClN₄OS

6-(Benzylthio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C12H10N4OS, CAS 877630-32-5

6-(Benzylthio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 877630-32-5C₁₂H₁₀N₄OS

6-((4-Chlorobenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C12H9ClN4OS, CAS 877630-72-3

6-((4-Chlorobenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 877630-72-3C₁₂H₉ClN₄OS

6-(Benzylthio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C14H14N4O2S, CAS 946379-63-1

6-(Benzylthio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 946379-63-1C₁₄H₁₄N₄O₂S

6-((3-Fluorobenzyl)thio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C14H13FN4O2S, CAS 946255-18-1

6-((3-Fluorobenzyl)thio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 946255-18-1C₁₄H₁₃FN₄O₂S

6-((4-Fluorobenzyl)thio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C14H13FN4O2S, CAS 946332-88-3

6-((4-Fluorobenzyl)thio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 946332-88-3C₁₄H₁₃FN₄O₂S

1-(2-Hydroxyethyl)-6-((2-methylbenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C15H16N4O2S, CAS 946229-95-4

1-(2-Hydroxyethyl)-6-((2-methylbenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 946229-95-4C₁₅H₁₆N₄O₂S

1-(2-Hydroxyethyl)-6-((3-methylbenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C15H16N4O2S, CAS 946255-21-6

1-(2-Hydroxyethyl)-6-((3-methylbenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 946255-21-6C₁₅H₁₆N₄O₂S

6-((2,5-Dimethylbenzyl)thio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C16H18N4O2S, CAS 946332-92-9

6-((2,5-Dimethylbenzyl)thio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 946332-92-9C₁₆H₁₈N₄O₂S

1-(2-Hydroxyethyl)-6-((4-methylbenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C15H16N4O2S, CAS 946379-69-7

1-(2-Hydroxyethyl)-6-((4-methylbenzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 946379-69-7C₁₅H₁₆N₄O₂S

1-(2-Hydroxyethyl)-6-((3-(trifluoromethyl)benzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C15H13F3N4O2S, CAS 946229-99-8

1-(2-Hydroxyethyl)-6-((3-(trifluoromethyl)benzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 946229-99-8C₁₅H₁₃F₃N₄O₂S

1-(2-Hydroxyethyl)-6-((4-(trifluoromethyl)benzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C15H13F3N4O2S, CAS 946255-24-9

1-(2-Hydroxyethyl)-6-((4-(trifluoromethyl)benzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 946255-24-9C₁₅H₁₃F₃N₄O₂S

6-((2-Fluorobenzyl)thio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C14H13FN4O2S, CAS 946332-96-3

6-((2-Fluorobenzyl)thio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 946332-96-3C₁₄H₁₃FN₄O₂S

6-((3,5-Dimethoxybenzyl)thio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C16H18N4O4S, CAS 946255-30-7

6-((3,5-Dimethoxybenzyl)thio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 946255-30-7C₁₆H₁₈N₄O₄S

6-((3,4-Dichlorobenzyl)thio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C14H12Cl2N4O2S, CAS 946333-15-9

6-((3,4-Dichlorobenzyl)thio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 946333-15-9C₁₄H₁₂Cl₂N₄O₂S

6-((2,4-Dichlorobenzyl)thio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C14H12Cl2N4O2S, CAS 946255-42-1

6-((2,4-Dichlorobenzyl)thio)-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 946255-42-1C₁₄H₁₂Cl₂N₄O₂S

6-((4-(Trifluoromethyl)benzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one chemical structure, C13H9F3N4OS, CAS 877630-42-7

6-((4-(Trifluoromethyl)benzyl)thio)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

CAS 877630-42-7C₁₃H₉F₃N₄OS