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Murcko scaffold

Ring system with 2 rings and 11 atoms

53 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 11
Chemicals: 53
With full pages: 8

Scaffold SMILES

S=c1[nH]nc(-c2ccsc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold S=c1[nH]nc(-c2ccsc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 53 chemicals

4-Ethyl-5-(5-methylthien-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C9H11N3S2, CAS 438230-66-1

4-Ethyl-5-(5-methylthien-3-yl)-4H-1,2,4-triazole-3-thiol

CAS 438230-66-1C₉H₁₁N₃S₂

5-(4,5-Dimethylthiophen-3-yl)-4-ethyl-2,4-dihydro-3H-1,2,4-triazole-3-thione chemical structure, C10H13N3S2, CAS 438229-96-0

5-(4,5-Dimethylthiophen-3-yl)-4-ethyl-2,4-dihydro-3H-1,2,4-triazole-3-thione

CAS 438229-96-0C₁₀H₁₃N₃S₂

4-Ethyl-5-(5-ethylthien-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C10H13N3S2, CAS 438230-04-7

4-Ethyl-5-(5-ethylthien-3-yl)-4H-1,2,4-triazole-3-thiol

CAS 438230-04-7C₁₀H₁₃N₃S₂

4-Ethyl-5-(5-isopropylthien-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C11H15N3S2, CAS 438230-75-2

4-Ethyl-5-(5-isopropylthien-3-yl)-4H-1,2,4-triazole-3-thiol

CAS 438230-75-2C₁₁H₁₅N₃S₂

4-Allyl-5-(4-ethyl-5-methylthien-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C12H15N3S2, CAS 522597-63-3

4-Allyl-5-(4-ethyl-5-methylthien-3-yl)-4H-1,2,4-triazole-3-thiol

CAS 522597-63-3C₁₂H₁₅N₃S₂

3H-1,2,4-Triazole-3-thione, 5-(4,5-dimethyl-3-thienyl)-2,4-dihydro-4-(2-propen-1-yl)- chemical structure, C11H13N3S2, CAS 522597-54-2

3H-1,2,4-Triazole-3-thione, 5-(4,5-dimethyl-3-thienyl)-2,4-dihydro-4-(2-propen-1-yl)-

CAS 522597-54-2C₁₁H₁₃N₃S₂

4-Allyl-5-(5-ethylthien-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C11H13N3S2, CAS 522597-66-6

4-Allyl-5-(5-ethylthien-3-yl)-4H-1,2,4-triazole-3-thiol

CAS 522597-66-6C₁₁H₁₃N₃S₂

4-Isobutyl-5-(5-methyl-3-thienyl)-4H-1,2,4-triazol-3-yl hydrosulfide chemical structure, C11H15N3S2, CAS 438236-53-4

4-Isobutyl-5-(5-methyl-3-thienyl)-4H-1,2,4-triazol-3-yl hydrosulfide

CAS 438236-53-4C₁₁H₁₅N₃S₂

3-(4,5-Dimethylthiophen-3-yl)-4-(2-methylpropyl)-1H-1,2,4-triazole-5-thione chemical structure, C12H17N3S2, CAS 438235-86-0

3-(4,5-Dimethylthiophen-3-yl)-4-(2-methylpropyl)-1H-1,2,4-triazole-5-thione

CAS 438235-86-0C₁₂H₁₇N₃S₂

3-(4-Ethyl-5-methylthiophen-3-yl)-4-(2-methylpropyl)-1H-1,2,4-triazole-5-thione chemical structure, C13H19N3S2, CAS 438234-43-6

3-(4-Ethyl-5-methylthiophen-3-yl)-4-(2-methylpropyl)-1H-1,2,4-triazole-5-thione

CAS 438234-43-6C₁₃H₁₉N₃S₂

4-Isobutyl-5-(5-propyl-3-thienyl)-4H-1,2,4-triazol-3-yl hydrosulfide chemical structure, C13H19N3S2, CAS 438233-63-7

4-Isobutyl-5-(5-propyl-3-thienyl)-4H-1,2,4-triazol-3-yl hydrosulfide

CAS 438233-63-7C₁₃H₁₉N₃S₂

4-Butyl-3-(5-ethyl-3-thiophenyl)-1H-1,2,4-triazole-5-thione chemical structure, C12H17N3S2, CAS 438235-93-9

4-Butyl-3-(5-ethyl-3-thiophenyl)-1H-1,2,4-triazole-5-thione

CAS 438235-93-9C₁₂H₁₇N₃S₂

4-Butyl-3-(5-propan-2-yl-3-thiophenyl)-1H-1,2,4-triazole-5-thione chemical structure, C13H19N3S2, CAS 438234-78-7

4-Butyl-3-(5-propan-2-yl-3-thiophenyl)-1H-1,2,4-triazole-5-thione

CAS 438234-78-7C₁₃H₁₉N₃S₂

4-Butyl-3-(4,5-dimethylthiophen-3-yl)-1H-1,2,4-triazole-5-thione chemical structure, C12H17N3S2, CAS 438233-42-2

4-Butyl-3-(4,5-dimethylthiophen-3-yl)-1H-1,2,4-triazole-5-thione

CAS 438233-42-2C₁₂H₁₇N₃S₂

4-Butyl-3-(5-methylthiophen-3-yl)-1H-1,2,4-triazole-5-thione chemical structure, C11H15N3S2, CAS 438233-67-1

4-Butyl-3-(5-methylthiophen-3-yl)-1H-1,2,4-triazole-5-thione

CAS 438233-67-1C₁₁H₁₅N₃S₂

4-Butyl-3-(5-propylthiophen-3-yl)-1H-1,2,4-triazole-5-thione chemical structure, C13H19N3S2, CAS 438233-21-7

4-Butyl-3-(5-propylthiophen-3-yl)-1H-1,2,4-triazole-5-thione

CAS 438233-21-7C₁₃H₁₉N₃S₂

4-Allyl-5-(5-methylthien-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C10H11N3S2, CAS 588680-35-7

4-Allyl-5-(5-methylthien-3-yl)-4H-1,2,4-triazole-3-thiol

CAS 588680-35-7C₁₀H₁₁N₃S₂

4-Butyl-3-(4-ethyl-5-methylthiophen-3-yl)-1H-1,2,4-triazole-5-thione chemical structure, C13H19N3S2, CAS 438237-04-8

4-Butyl-3-(4-ethyl-5-methylthiophen-3-yl)-1H-1,2,4-triazole-5-thione

CAS 438237-04-8C₁₃H₁₉N₃S₂

4-Methyl-5-(5-methylthiophen-3-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione chemical structure, C8H9N3S2, CAS 588685-90-9

4-Methyl-5-(5-methylthiophen-3-yl)-2,4-dihydro-3H-1,2,4-triazole-3-thione

CAS 588685-90-9C₈H₉N₃S₂

5-(5-Methylthien-3-yl)-4-propyl-4H-1,2,4-triazole-3-thiol chemical structure, C10H13N3S2, CAS 667436-25-1

5-(5-Methylthien-3-yl)-4-propyl-4H-1,2,4-triazole-3-thiol

CAS 667436-25-1C₁₀H₁₃N₃S₂

5-(4-Ethyl-5-methylthien-3-yl)-4-methyl-4H-1,2,4-triazole-3-thiol chemical structure, C10H13N3S2, CAS 590376-88-8

5-(4-Ethyl-5-methylthien-3-yl)-4-methyl-4H-1,2,4-triazole-3-thiol

CAS 590376-88-8C₁₀H₁₃N₃S₂

4-Ethyl-5-(5-propylthien-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C11H15N3S2, CAS 438230-64-9

4-Ethyl-5-(5-propylthien-3-yl)-4H-1,2,4-triazole-3-thiol

CAS 438230-64-9C₁₁H₁₅N₃S₂

4-Ethyl-5-(4-ethyl-5-methylthien-3-yl)-4H-1,2,4-triazole-3-thiol chemical structure, C11H15N3S2, CAS 438228-34-3

4-Ethyl-5-(4-ethyl-5-methylthien-3-yl)-4H-1,2,4-triazole-3-thiol

CAS 438228-34-3C₁₁H₁₅N₃S₂

5-(5-Bromothiophen-3-yl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione chemical structure, C7H6BrN3S2, CAS 588687-43-8

5-(5-Bromothiophen-3-yl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione

CAS 588687-43-8C₇H₆BrN₃S₂