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Murcko scaffold

2-(Thiophen-2-yl)pyrrolidine scaffold

90 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
90
With full pages
12
Scaffold SMILES

c1csc(C2CCCN2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Thiophen-2-yl)pyrrolidine page
Murcko scaffold c1csc(C2CCCN2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 90 chemicals

2-(Thiophen-2-yl)pyrrolidine chemical structure, C8H11NS, CAS 90090-64-5
2-(Thiophen-2-yl)pyrrolidine
CAS 90090-64-5C8H11NS
(R)-2-(Thiophen-2-yl)pyrrolidine chemical structure, C8H11NS, CAS 154777-22-7
(R)-2-(Thiophen-2-yl)pyrrolidine
CAS 154777-22-7C8H11NS
(2s)-2-(Thiophen-2-yl)pyrrolidine chemical structure, C8H11NS, CAS 1212950-45-2
(2s)-2-(Thiophen-2-yl)pyrrolidine
CAS 1212950-45-2C8H11NS
2-(3-Methylthiophen-2-yl)pyrrolidine chemical structure, C9H13NS, CAS 524674-40-6
2-(3-Methylthiophen-2-yl)pyrrolidine
CAS 524674-40-6C9H13NS
2-(3-Bromothiophen-2-yl)pyrrolidine chemical structure, C8H10BrNS, CAS 524674-52-0
2-(3-Bromothiophen-2-yl)pyrrolidine
CAS 524674-52-0C8H10BrNS
2-(5-Chloro-2-thienyl)pyrrolidine chemical structure, C8H10ClNS, CAS 524674-42-8
2-(5-Chloro-2-thienyl)pyrrolidine
CAS 524674-42-8C8H10ClNS
2-(4-Methylthiophen-2-yl)pyrrolidine chemical structure, C9H13NS, CAS 524674-51-9
2-(4-Methylthiophen-2-yl)pyrrolidine
CAS 524674-51-9C9H13NS
2-(5-Bromothiophen-2-yl)pyrrolidine chemical structure, C8H10BrNS, CAS 524674-43-9
2-(5-Bromothiophen-2-yl)pyrrolidine
CAS 524674-43-9C8H10BrNS
2-(5-Methylthiophen-2-yl)pyrrolidine chemical structure, C9H13NS, CAS 524674-41-7
2-(5-Methylthiophen-2-yl)pyrrolidine
CAS 524674-41-7C9H13NS
(2R,3R,4S,5S)-2-(Hydroxymethyl)-5-(thiophen-2-yl)pyrrolidine-3,4-diol chemical structure, C9H13NO3S, CAS 747398-65-8
(2R,3R,4S,5S)-2-(Hydroxymethyl)-5-(thiophen-2-yl)pyrrolidine-3,4-diol
CAS 747398-65-8C9H13NO3S
(2R,3R,4S,5R)-2-(Hydroxymethyl)-5-thiophen-2-ylpyrrolidine-3,4-diol chemical structure, C9H13NO3S, CAS 180895-71-0
(2R,3R,4S,5R)-2-(Hydroxymethyl)-5-thiophen-2-ylpyrrolidine-3,4-diol
CAS 180895-71-0C9H13NO3S
tert-Butyl 2-(thiophen-2-yl)pyrrolidine-1-carboxylate chemical structure, C13H19NO2S, CAS 197247-38-4
tert-Butyl 2-(thiophen-2-yl)pyrrolidine-1-carboxylate
CAS 197247-38-4C13H19NO2S
rac-Ethyl (2R,5R)-5-(thiophen-2-yl)pyrrolidine-2-carboxylate chemical structure, C11H15NO2S, CAS 226973-90-6
rac-Ethyl (2R,5R)-5-(thiophen-2-yl)pyrrolidine-2-carboxylate
CAS 226973-90-6C11H15NO2S
2-(Thiophen-2-yl)pyrrolidine-1-carbaldehyde chemical structure, C9H11NOS, CAS 80574-67-0
2-(Thiophen-2-yl)pyrrolidine-1-carbaldehyde
CAS 80574-67-0C9H11NOS
1,1-Dimethyl-2-(thiophen-2-yl)pyrrolidin-1-ium iodide chemical structure, C10H16INS, CAS 113348-22-4
1,1-Dimethyl-2-(thiophen-2-yl)pyrrolidin-1-ium iodide
CAS 113348-22-4C10H16INS
2-Chloro-1-[2-(thiophen-2-yl)pyrrolidin-1-yl]ethan-1-one chemical structure, C10H12ClNOS, CAS 875160-60-4
2-Chloro-1-[2-(thiophen-2-yl)pyrrolidin-1-yl]ethan-1-one
CAS 875160-60-4C10H12ClNOS
2-(4-Bromothiophen-2-yl)pyrrolidine hydrochloride chemical structure, C8H11BrClNS, CAS 1177333-57-1
2-(4-Bromothiophen-2-yl)pyrrolidine hydrochloride
CAS 1177333-57-1C8H11BrClNS
2-(4-Bromothiophen-2-yl)pyrrolidine chemical structure, C8H10BrNS, CAS 914202-92-9
2-(4-Bromothiophen-2-yl)pyrrolidine
CAS 914202-92-9C8H10BrNS
Methyl 4-(hydroxymethyl)-1,2-dimethyl-5-(2-thienyl)-2-pyrrolidinecarboxylate chemical structure, C13H19NO3S, CAS 1052612-49-3
Methyl 4-(hydroxymethyl)-1,2-dimethyl-5-(2-thienyl)-2-pyrrolidinecarboxylate
CAS 1052612-49-3C13H19NO3S
1-(Methylsulfonyl)-2-(thiophen-2-yl)pyrrolidine chemical structure, C9H13NO2S2, CAS 950327-45-4
1-(Methylsulfonyl)-2-(thiophen-2-yl)pyrrolidine
CAS 950327-45-4C9H13NO2S2
2-(4,5-Dimethylthiophen-2-yl)pyrrolidine chemical structure, C10H15NS, CAS 1018163-24-0
2-(4,5-Dimethylthiophen-2-yl)pyrrolidine
CAS 1018163-24-0C10H15NS
1-(2-(Thiophen-2-yl)pyrrolidin-1-yl)ethanone chemical structure, C10H13NOS, CAS 1090985-98-0
1-(2-(Thiophen-2-yl)pyrrolidin-1-yl)ethanone
CAS 1090985-98-0C10H13NOS
N-[2-(2-Chloropropanoylamino)ethyl]-2-thiophen-2-ylpyrrolidine-1-carboxamide chemical structure, C14H20ClN3O2S, CAS 1089548-24-2
N-[2-(2-Chloropropanoylamino)ethyl]-2-thiophen-2-ylpyrrolidine-1-carboxamide
CAS 1089548-24-2C14H20ClN3O2S
5-(Pyrrolidin-2-yl)thiophene-2-carboxylic acid chemical structure, C9H11NO2S, CAS 915923-83-0
5-(Pyrrolidin-2-yl)thiophene-2-carboxylic acid
CAS 915923-83-0C9H11NO2S