CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 10 atoms

138 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
138
With full pages
3
Scaffold SMILES

c1csc(C2CCCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1csc(C2CCCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 138 chemicals

1-Thiophen-2-ylcyclopentane-1-carboxamide chemical structure, C10H13NOS, CAS 59397-13-6
1-Thiophen-2-ylcyclopentane-1-carboxamide
CAS 59397-13-6C10H13NOS
2-(2-Hydroxycyclopentyl)-thiophene chemical structure, C9H12OS, CAS 115754-92-2
2-(2-Hydroxycyclopentyl)-thiophene
CAS 115754-92-2C9H12OS
Ethyl 2-amino-5-cyclopentylthiophene-3-carboxylate chemical structure, C12H17NO2S, CAS 158461-01-9
Ethyl 2-amino-5-cyclopentylthiophene-3-carboxylate
CAS 158461-01-9C12H17NO2S
1-(Thiophen-2-yl)cyclopentan-1-amine chemical structure, C9H13NS, CAS 59397-18-1
1-(Thiophen-2-yl)cyclopentan-1-amine
CAS 59397-18-1C9H13NS
trans-2-(2-Thienyl)cyclopentanol chemical structure, C9H12OS, CAS 119067-86-6
trans-2-(2-Thienyl)cyclopentanol
CAS 119067-86-6C9H12OS
(1-(Thiophen-2-yl)cyclopentyl)methanamine chemical structure, C10H15NS, CAS 75180-54-0
(1-(Thiophen-2-yl)cyclopentyl)methanamine
CAS 75180-54-0C10H15NS
[1-(5-Chlorothiophen-2-yl)cyclopentyl]methanamine chemical structure, C10H14ClNS, CAS 937651-31-5
[1-(5-Chlorothiophen-2-yl)cyclopentyl]methanamine
CAS 937651-31-5C10H14ClNS
2-Amino-5-cyclopentylthiophene-3-carbonitrile chemical structure, C10H12N2S, CAS 612504-42-4
2-Amino-5-cyclopentylthiophene-3-carbonitrile
CAS 612504-42-4C10H12N2S
5-Cyclopentylthiophene-2-carbaldehyde chemical structure, C10H12OS, CAS 959236-99-8
5-Cyclopentylthiophene-2-carbaldehyde
CAS 959236-99-8C10H12OS
1-(Thiophen-2-yl)cyclopentane-1-carboxylic acid chemical structure, C10H12O2S, CAS 202737-46-0
1-(Thiophen-2-yl)cyclopentane-1-carboxylic acid
CAS 202737-46-0C10H12O2S
2,2-Dimethyl-N-{[1-(thiophen-2-yl)cyclopentyl]methyl}propanamide chemical structure, C15H23NOS, CAS 1058459-36-1
2,2-Dimethyl-N-{[1-(thiophen-2-yl)cyclopentyl]methyl}propanamide
CAS 1058459-36-1C15H23NOS
N-(2-Methoxyethyl)-N'-{[1-(thiophen-2-yl)cyclopentyl]methyl}ethanediamide chemical structure, C15H22N2O3S, CAS 1058249-35-6
N-(2-Methoxyethyl)-N'-{[1-(thiophen-2-yl)cyclopentyl]methyl}ethanediamide
CAS 1058249-35-6C15H22N2O3S
N-Methyl-N'-{[1-(thiophen-2-yl)cyclopentyl]methyl}ethanediamide chemical structure, C13H18N2O2S, CAS 1058184-66-9
N-Methyl-N'-{[1-(thiophen-2-yl)cyclopentyl]methyl}ethanediamide
CAS 1058184-66-9C13H18N2O2S
Rac-(1r,2r)-2-(thiophen-2-yl)cyclopentan-1-ol chemical structure, C9H12OS, CAS 1932518-72-3
Rac-(1r,2r)-2-(thiophen-2-yl)cyclopentan-1-ol
CAS 1932518-72-3C9H12OS
N-Propyl-1-(thiophen-2-yl)cyclopentanecarboxamide chemical structure, C13H19NOS, CAS 1049574-56-2
N-Propyl-1-(thiophen-2-yl)cyclopentanecarboxamide
CAS 1049574-56-2C13H19NOS
N-Isopentyl-1-(thiophen-2-yl)cyclopentanecarboxamide chemical structure, C15H23NOS, CAS 1049574-72-2
N-Isopentyl-1-(thiophen-2-yl)cyclopentanecarboxamide
CAS 1049574-72-2C15H23NOS
N-Butyl-1-(thiophen-2-yl)cyclopentanecarboxamide chemical structure, C14H21NOS, CAS 1049524-65-3
N-Butyl-1-(thiophen-2-yl)cyclopentanecarboxamide
CAS 1049524-65-3C14H21NOS
N-(2-Methoxyethyl)-1-(thiophen-2-yl)cyclopentanecarboxamide chemical structure, C13H19NO2S, CAS 1049512-14-2
N-(2-Methoxyethyl)-1-(thiophen-2-yl)cyclopentanecarboxamide
CAS 1049512-14-2C13H19NO2S
N-(2,2-Dimethoxyethyl)-1-(thiophen-2-yl)cyclopentanecarboxamide chemical structure, C14H21NO3S, CAS 1049513-05-4
N-(2,2-Dimethoxyethyl)-1-(thiophen-2-yl)cyclopentanecarboxamide
CAS 1049513-05-4C14H21NO3S
N-Isopropyl-1-(thiophen-2-yl)cyclopentanecarboxamide chemical structure, C13H19NOS, CAS 1049554-54-2
N-Isopropyl-1-(thiophen-2-yl)cyclopentanecarboxamide
CAS 1049554-54-2C13H19NOS
N-(tert-Butyl)-1-(thiophen-2-yl)cyclopentanecarboxamide chemical structure, C14H21NOS, CAS 1049526-26-2
N-(tert-Butyl)-1-(thiophen-2-yl)cyclopentanecarboxamide
CAS 1049526-26-2C14H21NOS
N-Isobutyl-1-(thiophen-2-yl)cyclopentanecarboxamide chemical structure, C14H21NOS, CAS 1049554-61-1
N-Isobutyl-1-(thiophen-2-yl)cyclopentanecarboxamide
CAS 1049554-61-1C14H21NOS
1-(Thiophen-2-yl)cyclopentan-1-amine hydrochloride chemical structure, C9H14ClNS, CAS 1222098-25-0
1-(Thiophen-2-yl)cyclopentan-1-amine hydrochloride
CAS 1222098-25-0C9H14ClNS
1-(2-Thienyl)cyclopentanecarbonyl chloride chemical structure, C10H11ClOS, CAS 54529-98-5
1-(2-Thienyl)cyclopentanecarbonyl chloride
CAS 54529-98-5C10H11ClOS