CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 19 atoms

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
27
With full pages
8
Scaffold SMILES

O=S(=O)(Nc1ccc2[nH]cnc2c1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(Nc1ccc2[nH]cnc2c1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

N-(1-tert-Butylbenzimidazol-5-yl)-4-methylbenzenesulfonamide chemical structure, C18H21N3O2S, CAS 292052-61-0
N-(1-tert-Butylbenzimidazol-5-yl)-4-methylbenzenesulfonamide
CAS 292052-61-0C18H21N3O2S
4-Methyl-N-(1-methylbenzimidazol-5-yl)benzenesulfonamide chemical structure, C15H15N3O2S, CAS 5564-03-4
4-Methyl-N-(1-methylbenzimidazol-5-yl)benzenesulfonamide
CAS 5564-03-4C15H15N3O2S
N-(1,2-Dimethylbenzimidazol-5-yl)-4-methylbenzenesulfonamide chemical structure, C16H17N3O2S, CAS 37739-79-0
N-(1,2-Dimethylbenzimidazol-5-yl)-4-methylbenzenesulfonamide
CAS 37739-79-0C16H17N3O2S
N-[2-(Trifluoromethyl)-1H-benzimidazol-6-yl]benzenesulfonamide chemical structure, C14H10F3N3O2S, CAS 156493-93-5
N-[2-(Trifluoromethyl)-1H-benzimidazol-6-yl]benzenesulfonamide
CAS 156493-93-5C14H10F3N3O2S
N-(1,2-Dimethylbenzimidazol-5-yl)benzenesulfonamide chemical structure, C15H15N3O2S, CAS 488708-12-9
N-(1,2-Dimethylbenzimidazol-5-yl)benzenesulfonamide
CAS 488708-12-9C15H15N3O2S
N-(1-tert-Butylbenzimidazol-5-yl)benzenesulfonamide chemical structure, C17H19N3O2S, CAS 489462-62-6
N-(1-tert-Butylbenzimidazol-5-yl)benzenesulfonamide
CAS 489462-62-6C17H19N3O2S
N-[2-[5-(Benzenesulfonamido)-1-methylbenzimidazol-2-yl]ethyl]acetamide chemical structure, C18H20N4O3S, CAS 831238-57-4
N-[2-[5-(Benzenesulfonamido)-1-methylbenzimidazol-2-yl]ethyl]acetamide
CAS 831238-57-4C18H20N4O3S
4-Bromo-N-(1-methyl-1H-benzimidazol-5-yl)benzenesulfonamide chemical structure, C14H12BrN3O2S, CAS 487032-32-6
4-Bromo-N-(1-methyl-1H-benzimidazol-5-yl)benzenesulfonamide
CAS 487032-32-6C14H12BrN3O2S
4-Bromo-N-(1,2-dimethyl-1H-benzimidazol-5-yl)benzenesulfonamide chemical structure, C15H14BrN3O2S, CAS 489397-82-2
4-Bromo-N-(1,2-dimethyl-1H-benzimidazol-5-yl)benzenesulfonamide
CAS 489397-82-2C15H14BrN3O2S
4-Fluoro-N-[2-(trifluoromethyl)-1H-benzimidazol-6-yl]benzenesulfonamide chemical structure, C14H9F4N3O2S, CAS 1022428-34-7
4-Fluoro-N-[2-(trifluoromethyl)-1H-benzimidazol-6-yl]benzenesulfonamide
CAS 1022428-34-7C14H9F4N3O2S
N-(1-Ethylbenzimidazol-5-yl)-3-fluoro-4-methoxybenzenesulfonamide chemical structure, C16H16FN3O3S, CAS 879476-97-8
N-(1-Ethylbenzimidazol-5-yl)-3-fluoro-4-methoxybenzenesulfonamide
CAS 879476-97-8C16H16FN3O3S
N-(1H-Benzimidazol-6-yl)-4-methoxybenzenesulfonamide chemical structure, C14H13N3O3S, CAS 1219552-28-9
N-(1H-Benzimidazol-6-yl)-4-methoxybenzenesulfonamide
CAS 1219552-28-9C14H13N3O3S
4-Chloro-N-(2-methyl-1H-benzimidazol-6-yl)benzenesulfonamide chemical structure, C14H12ClN3O2S, CAS 1219564-14-3
4-Chloro-N-(2-methyl-1H-benzimidazol-6-yl)benzenesulfonamide
CAS 1219564-14-3C14H12ClN3O2S
N-(1H-Benzimidazol-6-yl)-4-chlorobenzenesulfonamide chemical structure, C13H10ClN3O2S, CAS 1219539-90-8
N-(1H-Benzimidazol-6-yl)-4-chlorobenzenesulfonamide
CAS 1219539-90-8C13H10ClN3O2S
N-[2-(Propan-2-yl)-1H-benzimidazol-6-yl]benzenesulfonamide chemical structure, C16H17N3O2S, CAS 1219572-43-6
N-[2-(Propan-2-yl)-1H-benzimidazol-6-yl]benzenesulfonamide
CAS 1219572-43-6C16H17N3O2S
2,5-Dichloro-N-(2-methyl-1H-benzimidazol-5-yl)benzenesulfonamide chemical structure, C14H11Cl2N3O2S, CAS 1232798-27-4
2,5-Dichloro-N-(2-methyl-1H-benzimidazol-5-yl)benzenesulfonamide
CAS 1232798-27-4C14H11Cl2N3O2S
N-[2-(Methoxymethyl)-1H-benzimidazol-5-yl]benzenesulfonamide chemical structure, C15H15N3O3S, CAS 1224160-28-4
N-[2-(Methoxymethyl)-1H-benzimidazol-5-yl]benzenesulfonamide
CAS 1224160-28-4C15H15N3O3S
4-Fluoro-N-(2-methyl-1H-benzimidazol-5-yl)benzenesulfonamide chemical structure, C14H12FN3O2S, CAS 1183575-67-8
4-Fluoro-N-(2-methyl-1H-benzimidazol-5-yl)benzenesulfonamide
CAS 1183575-67-8C14H12FN3O2S
4-Chloro-N-[2-(methoxymethyl)-1H-benzimidazol-6-yl]benzenesulfonamide chemical structure, C15H14ClN3O3S, CAS 1224154-89-5
4-Chloro-N-[2-(methoxymethyl)-1H-benzimidazol-6-yl]benzenesulfonamide
CAS 1224154-89-5C15H14ClN3O3S
4-Methoxy-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzenesulfonamide chemical structure, C16H17N3O4S, CAS 1232770-31-8
4-Methoxy-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzenesulfonamide
CAS 1232770-31-8C16H17N3O4S
4-Fluoro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzenesulfonamide chemical structure, C15H14FN3O3S, CAS 1232793-47-3
4-Fluoro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzenesulfonamide
CAS 1232793-47-3C15H14FN3O3S
2,5-Dichloro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzenesulfonamide chemical structure, C15H13Cl2N3O3S, CAS 1224160-94-4
2,5-Dichloro-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzenesulfonamide
CAS 1224160-94-4C15H13Cl2N3O3S
4-Bromo-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzenesulfonamide chemical structure, C15H14BrN3O3S, CAS 1232803-08-5
4-Bromo-N-[2-(methoxymethyl)-1H-benzimidazol-5-yl]benzenesulfonamide
CAS 1232803-08-5C15H14BrN3O3S
N-[4-({[2-tert-Butyl-1-(2-hydroxyethyl)-1H-benzimidazol-5-yl]amino}sulfonyl)phenyl]acetamide chemical structure, C21H26N4O4S, CAS 849351-69-5
N-[4-({[2-tert-Butyl-1-(2-hydroxyethyl)-1H-benzimidazol-5-yl]amino}sulfonyl)phenyl]acetamide
CAS 849351-69-5C21H26N4O4S