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Murcko scaffold

Ring system with 3 rings and 23 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
11
With full pages
7
Scaffold SMILES

O=S(=O)(Nc1ccc(Cc2ccncc2)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(Nc1ccc(Cc2ccncc2)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

4-Chloro-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide chemical structure, C18H15ClN2O2S, CAS 282104-97-6
4-Chloro-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide
CAS 282104-97-6C18H15ClN2O2S
4-Chloro-2,5-dimethoxy-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide chemical structure, C20H19ClN2O4S, CAS 381193-35-7
4-Chloro-2,5-dimethoxy-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide
CAS 381193-35-7C20H19ClN2O4S
N-[4-[[4-(Pyridin-4-ylmethyl)phenyl]sulfamoyl]phenyl]acetamide chemical structure, C20H19N3O3S, CAS 445228-61-5
N-[4-[[4-(Pyridin-4-ylmethyl)phenyl]sulfamoyl]phenyl]acetamide
CAS 445228-61-5C20H19N3O3S
4-Bromo-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide chemical structure, C18H15BrN2O2S, CAS 445228-64-8
4-Bromo-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide
CAS 445228-64-8C18H15BrN2O2S
4-Methoxy-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide chemical structure, C19H18N2O3S, CAS 720668-18-8
4-Methoxy-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide
CAS 720668-18-8C19H18N2O3S
4-Methoxy-3-methyl-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide chemical structure, C20H20N2O3S, CAS 632294-11-2
4-Methoxy-3-methyl-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide
CAS 632294-11-2C20H20N2O3S
4-Methylsulfanyl-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide chemical structure, C19H18N2O2S2, CAS 727674-09-1
4-Methylsulfanyl-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide
CAS 727674-09-1C19H18N2O2S2
3,4-Dimethoxy-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide chemical structure, C20H20N2O4S, CAS 727674-52-4
3,4-Dimethoxy-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide
CAS 727674-52-4C20H20N2O4S
5-Ethyl-2-methoxy-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide chemical structure, C21H22N2O3S, CAS 727674-59-1
5-Ethyl-2-methoxy-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide
CAS 727674-59-1C21H22N2O3S
3,4-Dichloro-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide chemical structure, C18H14Cl2N2O2S, CAS 445228-65-9
3,4-Dichloro-N-[4-(pyridin-4-ylmethyl)phenyl]benzenesulfonamide
CAS 445228-65-9C18H14Cl2N2O2S
5-Chloro-2-methyl-N-[4-(4-pyridinylmethyl)phenyl]benzenesulfonamide chemical structure, C19H17ClN2O2S, CAS 1260704-14-0
5-Chloro-2-methyl-N-[4-(4-pyridinylmethyl)phenyl]benzenesulfonamide
CAS 1260704-14-0C19H17ClN2O2S