CompoundList
Sign in
Murcko scaffold

2-Oxabicyclo[2.2.2]octane scaffold

275 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
8
Chemicals
275
With full pages
67
Scaffold SMILES

C1CC2CCC1CO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Oxabicyclo[2.2.2]octane page
Murcko scaffold C1CC2CCC1CO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 275 chemicals

tert-Butyl N-{[4-(aminomethyl)-2-oxabicyclo[2.2.2]octan-1-yl]methyl}carbamate hydrochloride chemical structure, C14H27ClN2O3, CAS 2260932-09-8
tert-Butyl N-{[4-(aminomethyl)-2-oxabicyclo[2.2.2]octan-1-yl]methyl}carbamate hydrochloride
CAS 2260932-09-8C14H27ClN2O3
tert-Butyl N-{[4-(aminomethyl)-2-oxabicyclo[2.2.2]octan-1-yl]methyl}carbamate chemical structure, C14H26N2O3, CAS 2260931-92-6
tert-Butyl N-{[4-(aminomethyl)-2-oxabicyclo[2.2.2]octan-1-yl]methyl}carbamate
CAS 2260931-92-6C14H26N2O3
(1-Methyl-2-oxabicyclo(2.2.2)octan-4-yl)methanamine hydrochloride chemical structure, C9H18ClNO, CAS 2174007-99-7
(1-Methyl-2-oxabicyclo(2.2.2)octan-4-yl)methanamine hydrochloride
CAS 2174007-99-7C9H18ClNO
rac-(1R,4S,6R)-3,3-Dimethyl-2-oxabicyclo[2.2.2]octan-6-ol chemical structure, C9H16O2, CAS 2173999-91-0
rac-(1R,4S,6R)-3,3-Dimethyl-2-oxabicyclo[2.2.2]octan-6-ol
CAS 2173999-91-0C9H16O2
1-({[(tert-Butoxy)carbonyl]amino}methyl)-2-oxabicyclo[2.2.2]octane-4-carboxylic acid chemical structure, C14H23NO5, CAS 2243516-55-2
1-({[(tert-Butoxy)carbonyl]amino}methyl)-2-oxabicyclo[2.2.2]octane-4-carboxylic acid
CAS 2243516-55-2C14H23NO5
(4-Methyl-2-oxabicyclo[2.2.2]octan-1-yl)methanamine chemical structure, C9H17NO, CAS 2247104-17-0
(4-Methyl-2-oxabicyclo[2.2.2]octan-1-yl)methanamine
CAS 2247104-17-0C9H17NO
1-{4-Methyl-2-oxabicyclo[2.2.2]octan-1-yl}methanamine hydrochloride chemical structure, C9H18ClNO, CAS 2247104-20-5
1-{4-Methyl-2-oxabicyclo[2.2.2]octan-1-yl}methanamine hydrochloride
CAS 2247104-20-5C9H18ClNO
4-Methyl-2-oxabicyclo(2.2.2)octane-1-carboxylic acid chemical structure, C9H14O3, CAS 2247107-46-4
4-Methyl-2-oxabicyclo(2.2.2)octane-1-carboxylic acid
CAS 2247107-46-4C9H14O3
1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane-4-carboxylic acid chemical structure, C11H18O3, CAS 2243512-23-2
1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane-4-carboxylic acid
CAS 2243512-23-2C11H18O3
{4-Methyl-2-oxabicyclo[2.2.2]octan-1-yl}methanesulfonylchloride chemical structure, C9H15ClO3S, CAS 2247103-47-3
{4-Methyl-2-oxabicyclo[2.2.2]octan-1-yl}methanesulfonylchloride
CAS 2247103-47-3C9H15ClO3S
tert-Butyl N-({4-amino-2-oxabicyclo[2.2.2]octan-1-yl}methyl)carbamate hydrochloride chemical structure, C13H25ClN2O3, CAS 2248271-12-5
tert-Butyl N-({4-amino-2-oxabicyclo[2.2.2]octan-1-yl}methyl)carbamate hydrochloride
CAS 2248271-12-5C13H25ClN2O3
tert-Butyl N-((4-amino-2-oxabicyclo(2.2.2)octan-1-yl)methyl)carbamate chemical structure, C13H24N2O3, CAS 2248271-11-4
tert-Butyl N-((4-amino-2-oxabicyclo(2.2.2)octan-1-yl)methyl)carbamate
CAS 2248271-11-4C13H24N2O3
Ethyl 1-(aminomethyl)-3,3-dimethyl-2-oxabicyclo[2.2.2]octane-4-carboxylate hydrochloride chemical structure, C13H24ClNO3, CAS 2248289-41-8
Ethyl 1-(aminomethyl)-3,3-dimethyl-2-oxabicyclo[2.2.2]octane-4-carboxylate hydrochloride
CAS 2248289-41-8C13H24ClNO3
Ethyl 1-(aminomethyl)-3,3-dimethyl-2-oxabicyclo[2.2.2]octane-4-carboxylate chemical structure, C13H23NO3, CAS 2248284-25-3
Ethyl 1-(aminomethyl)-3,3-dimethyl-2-oxabicyclo[2.2.2]octane-4-carboxylate
CAS 2248284-25-3C13H23NO3
Methyl 4-(hydroxymethyl)-2-oxabicyclo(2.2.2)octane-1-carboxylate chemical structure, C10H16O4, CAS 2315282-07-4
Methyl 4-(hydroxymethyl)-2-oxabicyclo(2.2.2)octane-1-carboxylate
CAS 2315282-07-4C10H16O4
4-Amino-2-oxabicyclo[2.2.2]octane-1-carboxylic acid hydrochloride chemical structure, C8H14ClNO3, CAS 2315282-10-9
4-Amino-2-oxabicyclo[2.2.2]octane-1-carboxylic acid hydrochloride
CAS 2315282-10-9C8H14ClNO3
4-Amino-2-oxabicyclo[2.2.2]octane-1-carboxylic acid chemical structure, C8H13NO3, CAS 2167749-17-7
4-Amino-2-oxabicyclo[2.2.2]octane-1-carboxylic acid
CAS 2167749-17-7C8H13NO3
Methyl 4-hydroxy-2-oxabicyclo[2.2.2]octane-1-carboxylate chemical structure, C9H14O4, CAS 2315282-36-9
Methyl 4-hydroxy-2-oxabicyclo[2.2.2]octane-1-carboxylate
CAS 2315282-36-9C9H14O4
4-Hydroxy-2-oxabicyclo[2.2.2]octane-1-carboxylic acid chemical structure, C8H12O4, CAS 2315282-11-0
4-Hydroxy-2-oxabicyclo[2.2.2]octane-1-carboxylic acid
CAS 2315282-11-0C8H12O4
Methyl 4-(tert-butoxycarbonylamino)-2-oxabicyclo[2.2.2]octane-1-carboxylate chemical structure, C14H23NO5, CAS 2205097-75-0
Methyl 4-(tert-butoxycarbonylamino)-2-oxabicyclo[2.2.2]octane-1-carboxylate
CAS 2205097-75-0C14H23NO5
Methyl 4-amino-2-oxabicyclo[2.2.2]octane-1-carboxylate hydrochloride chemical structure, C9H16ClNO3, CAS 2320469-53-0
Methyl 4-amino-2-oxabicyclo[2.2.2]octane-1-carboxylate hydrochloride
CAS 2320469-53-0C9H16ClNO3
Methyl 4-amino-2-oxabicyclo[2.2.2]octane-1-carboxylate chemical structure, C9H15NO3, CAS 2320469-52-9
Methyl 4-amino-2-oxabicyclo[2.2.2]octane-1-carboxylate
CAS 2320469-52-9C9H15NO3
Methyl 1-vinyl-2-oxabicyclo[2.2.2]octane-4-carboxylate chemical structure, C11H16O3, CAS 2387596-36-1
Methyl 1-vinyl-2-oxabicyclo[2.2.2]octane-4-carboxylate
CAS 2387596-36-1C11H16O3
[4-(Hydroxymethyl)-2-oxabicyclo[2.2.2]octan-1-yl]methyl acetate chemical structure, C11H18O4, CAS 2411640-15-6
[4-(Hydroxymethyl)-2-oxabicyclo[2.2.2]octan-1-yl]methyl acetate
CAS 2411640-15-6C11H18O4