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Murcko scaffold

2-Oxabicyclo[2.2.2]octane scaffold

275 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
8
Chemicals
275
With full pages
67
Scaffold SMILES

C1CC2CCC1CO2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Oxabicyclo[2.2.2]octane page
Murcko scaffold C1CC2CCC1CO2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 275 chemicals

tert-Butyl (1-vinyl-2-oxabicyclo[2.2.2]octan-4-yl)carbamate chemical structure, C14H23NO3, CAS 1416374-98-5
tert-Butyl (1-vinyl-2-oxabicyclo[2.2.2]octan-4-yl)carbamate
CAS 1416374-98-5C14H23NO3
(1S,4R,6S)-3,3-Dimethyl-2-oxabicyclo[2.2.2]octan-6-ol chemical structure, C9H16O2, CAS 118389-15-4
(1S,4R,6S)-3,3-Dimethyl-2-oxabicyclo[2.2.2]octan-6-ol
CAS 118389-15-4C9H16O2
3,3-Dimethyl-2-oxabicyclo[2.2.2]octane-1-carboxylic acid chemical structure, C10H16O3, CAS 149194-97-8
3,3-Dimethyl-2-oxabicyclo[2.2.2]octane-1-carboxylic acid
CAS 149194-97-8C10H16O3
2-Oxabicyclo[2.2.2]octan-6-ol, 1,3-dimethyl-3-(4-methyl-3-pentenyl)- chemical structure, C15H26O2, CAS 59861-08-4
2-Oxabicyclo[2.2.2]octan-6-ol, 1,3-dimethyl-3-(4-methyl-3-pentenyl)-
CAS 59861-08-4C15H26O2
tert-Butyl (1-acetyl-2-oxabicyclo[2.2.2]octan-4-yl)carbamate chemical structure, C14H23NO4, CAS 1417553-59-3
tert-Butyl (1-acetyl-2-oxabicyclo[2.2.2]octan-4-yl)carbamate
CAS 1417553-59-3C14H23NO4
tert-Butyl (1-formyl-2-oxabicyclo[2.2.2]octan-4-yl)carbamate chemical structure, C13H21NO4, CAS 1417551-42-8
tert-Butyl (1-formyl-2-oxabicyclo[2.2.2]octan-4-yl)carbamate
CAS 1417551-42-8C13H21NO4
1-(Iodomethyl)-2-oxabicyclo(2.2.2)octane chemical structure, C8H13IO, CAS 1447943-01-2
1-(Iodomethyl)-2-oxabicyclo(2.2.2)octane
CAS 1447943-01-2C8H13IO
(2-Oxabicyclo(2.2.2)octan-1-yl)methanol chemical structure, C8H14O2, CAS 1447943-03-4
(2-Oxabicyclo(2.2.2)octan-1-yl)methanol
CAS 1447943-03-4C8H14O2
2-Oxabicyclo(2.2.2)octane-1-carboxylic acid chemical structure, C8H12O3, CAS 1447943-57-8
2-Oxabicyclo(2.2.2)octane-1-carboxylic acid
CAS 1447943-57-8C8H12O3
tert-Butyl N-[1-(hydroxymethyl)-2-oxabicyclo[2.2.2]octan-4-yl]carbamate chemical structure, C13H23NO4, CAS 1417556-03-6
tert-Butyl N-[1-(hydroxymethyl)-2-oxabicyclo[2.2.2]octan-4-yl]carbamate
CAS 1417556-03-6C13H23NO4
tert-Butyl N-[1-(aminomethyl)-2-oxabicyclo[2.2.2]octan-4-yl]carbamate chemical structure, C13H24N2O3, CAS 1417551-73-5
tert-Butyl N-[1-(aminomethyl)-2-oxabicyclo[2.2.2]octan-4-yl]carbamate
CAS 1417551-73-5C13H24N2O3
tert-Butyl N-[1-(azidomethyl)-2-oxabicyclo[2.2.2]octan-4-yl]carbamate chemical structure, C13H22N4O3, CAS 1417551-72-4
tert-Butyl N-[1-(azidomethyl)-2-oxabicyclo[2.2.2]octan-4-yl]carbamate
CAS 1417551-72-4C13H22N4O3
(1R,4S,6S)-1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-6-yl acetate chemical structure, C12H20O3, CAS 57709-95-2
(1R,4S,6S)-1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-6-yl acetate
CAS 57709-95-2C12H20O3
rel-(1R,4S,5R)-1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-5-ol chemical structure, C10H18O2, CAS 81801-58-3
rel-(1R,4S,5R)-1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octan-5-ol
CAS 81801-58-3C10H18O2
2-Hydroxy-1,8-cineole chemical structure, C10H18O2
2-Hydroxy-1,8-cineole
C10H18O2
1-(Methoxycarbonyl)-2-oxabicyclo(2.2.2)octane-4-carboxylic acid chemical structure, C10H14O5, CAS 1801203-48-4
1-(Methoxycarbonyl)-2-oxabicyclo(2.2.2)octane-4-carboxylic acid
CAS 1801203-48-4C10H14O5
3,3-Dimethyl-2-oxabicyclo[2.2.2]octan-6-ol chemical structure, C9H16O2, CAS 2307751-31-9
3,3-Dimethyl-2-oxabicyclo[2.2.2]octan-6-ol
CAS 2307751-31-9C9H16O2
4-{[(tert-Butoxy)carbonyl]amino}-2-oxabicyclo[2.2.2]octane-1-carboxylic acid chemical structure, C13H21NO5, CAS 2010218-26-3
4-{[(tert-Butoxy)carbonyl]amino}-2-oxabicyclo[2.2.2]octane-1-carboxylic acid
CAS 2010218-26-3C13H21NO5
1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane-6-ethanamine chemical structure, C12H23NO, CAS 52480-35-0
1,3,3-Trimethyl-2-oxabicyclo[2.2.2]octane-6-ethanamine
CAS 52480-35-0C12H23NO
(1S,4R,6R)-6-Hydroxy-2-oxabicyclo[2.2.2]octane-4-carbonitrile chemical structure, C8H11NO2
(1S,4R,6R)-6-Hydroxy-2-oxabicyclo[2.2.2]octane-4-carbonitrile
C8H11NO2
rac-(1R,4S,6R)-2-Oxabicyclo[2.2.2]octan-6-ol chemical structure, C7H12O2, CAS 107598-07-2
rac-(1R,4S,6R)-2-Oxabicyclo[2.2.2]octan-6-ol
CAS 107598-07-2C7H12O2
1-(Difluoromethyl)-2-oxabicyclo[2.2.2]octan-4-amine hydrochloride chemical structure, C8H14ClF2NO, CAS 2170372-49-1
1-(Difluoromethyl)-2-oxabicyclo[2.2.2]octan-4-amine hydrochloride
CAS 2170372-49-1C8H14ClF2NO
1-(Difluoromethyl)-2-oxabicyclo[2.2.2]octan-4-amine chemical structure, C8H13F2NO, CAS 2170372-48-0
1-(Difluoromethyl)-2-oxabicyclo[2.2.2]octan-4-amine
CAS 2170372-48-0C8H13F2NO
{4-Amino-2-oxabicyclo[2.2.2]octan-1-yl}methanol chemical structure, C8H15NO2, CAS 2170372-44-6
{4-Amino-2-oxabicyclo[2.2.2]octan-1-yl}methanol
CAS 2170372-44-6C8H15NO2