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Murcko scaffold

1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole scaffold

272 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
272
With full pages
23
Scaffold SMILES

c1n[nH]c2c1CNC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazole page
Murcko scaffold c1n[nH]c2c1CNC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 272 chemicals

Methyl 2-methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylate chemical structure, C8H11N3O2, CAS 1779942-62-9
Methyl 2-methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylate
CAS 1779942-62-9C8H11N3O2
Methyl 1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylate chemical structure, C8H11N3O2, CAS 1784927-16-7
Methyl 1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylate
CAS 1784927-16-7C8H11N3O2
3-Bromo-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole chemical structure, C5H6BrN3, CAS 1781305-41-6
3-Bromo-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole
CAS 1781305-41-6C5H6BrN3
3-Bromo-5-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole chemical structure, C6H8BrN3, CAS 1785086-74-9
3-Bromo-5-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole
CAS 1785086-74-9C6H8BrN3
3-Bromo-1,5-dimethyl-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazole chemical structure, C7H10BrN3, CAS 1780907-46-1
3-Bromo-1,5-dimethyl-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazole
CAS 1780907-46-1C7H10BrN3
3-Bromo-2,5-dimethyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole chemical structure, C7H10BrN3, CAS 1784344-36-0
3-Bromo-2,5-dimethyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole
CAS 1784344-36-0C7H10BrN3
tert-Butyl 3-amino-1-ethyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-5-carboxylate chemical structure, C12H20N4O2, CAS 1784580-01-3
tert-Butyl 3-amino-1-ethyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-5-carboxylate
CAS 1784580-01-3C12H20N4O2
tert-Butyl 3-bromo-4,6-dihydropyrrolo(3,4-c)pyrazole-5(1H)-carboxylate chemical structure, C10H14BrN3O2, CAS 1784831-22-6
tert-Butyl 3-bromo-4,6-dihydropyrrolo(3,4-c)pyrazole-5(1H)-carboxylate
CAS 1784831-22-6C10H14BrN3O2
3-Iodo-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole chemical structure, C5H6IN3, CAS 2133368-36-0
3-Iodo-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole
CAS 2133368-36-0C5H6IN3
5-tert-Butyl 3-ethyl 2-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-3,5(2H)-dicarboxylate chemical structure, C14H21N3O4, CAS 1422344-18-0
5-tert-Butyl 3-ethyl 2-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-3,5(2H)-dicarboxylate
CAS 1422344-18-0C14H21N3O4
5-tert-Butyl 1-ethyl 3-amino-6-isopropylpyrrolo[3,4-c]pyrazole-1,5(4H,6H)-dicarboxylate chemical structure, C16H26N4O4, CAS 1956331-22-8
5-tert-Butyl 1-ethyl 3-amino-6-isopropylpyrrolo[3,4-c]pyrazole-1,5(4H,6H)-dicarboxylate
CAS 1956331-22-8C16H26N4O4
Di-tert-butyl 3-bromo-6,6-dimethylpyrrolo[3,4-c]pyrazole-2,5(4H,6H)-dicarboxylate chemical structure, C17H26BrN3O4, CAS 1330766-42-1
Di-tert-butyl 3-bromo-6,6-dimethylpyrrolo[3,4-c]pyrazole-2,5(4H,6H)-dicarboxylate
CAS 1330766-42-1C17H26BrN3O4
tert-Butyl 2-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate chemical structure, C11H17N3O2, CAS 1369921-82-3
tert-Butyl 2-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate
CAS 1369921-82-3C11H17N3O2
tert-Butyl 3-chloro-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxylate chemical structure, C10H14ClN3O2, CAS 2089377-13-7
tert-Butyl 3-chloro-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxylate
CAS 2089377-13-7C10H14ClN3O2
2-Methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-3-amine dihydrochloride chemical structure, C6H12Cl2N4, CAS 1909324-81-7
2-Methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-3-amine dihydrochloride
CAS 1909324-81-7C6H12Cl2N4
1-Methyl-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-3-amine dihydrochloride chemical structure, C6H12Cl2N4, CAS 1909324-73-7
1-Methyl-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazol-3-amine dihydrochloride
CAS 1909324-73-7C6H12Cl2N4
3-(Methoxymethyl)-1,4,5,6-tetrahydropyrrolo[3,4-C]pyrazole chemical structure, C7H11N3O, CAS 2092105-39-8
3-(Methoxymethyl)-1,4,5,6-tetrahydropyrrolo[3,4-C]pyrazole
CAS 2092105-39-8C7H11N3O
tert-Butyl 3-amino-6,6-dimethyl-1-(propionyloxy)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxylate chemical structure, C15H24N4O4, CAS 2007915-99-1
tert-Butyl 3-amino-6,6-dimethyl-1-(propionyloxy)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(1H)-carboxylate
CAS 2007915-99-1C15H24N4O4
tert-Butyl 3-amino-6,6-dimethyl-2-(propionyloxy)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate chemical structure, C15H24N4O4, CAS 2007916-02-9
tert-Butyl 3-amino-6,6-dimethyl-2-(propionyloxy)-4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate
CAS 2007916-02-9C15H24N4O4
1-{1-Methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-5-yl}prop-2-en-1-one chemical structure, C9H11N3O, CAS 2094346-16-2
1-{1-Methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-5-yl}prop-2-en-1-one
CAS 2094346-16-2C9H11N3O
5-(tert-Butyl) 1-ethyl 3-amino-6,6-dimethyl-4,6-dihydropyrrolo[3,4-c]pyrazole-1,5-dicarboxylate hydrochloride chemical structure, C15H25ClN4O4, CAS 2444880-17-3
5-(tert-Butyl) 1-ethyl 3-amino-6,6-dimethyl-4,6-dihydropyrrolo[3,4-c]pyrazole-1,5-dicarboxylate hydrochloride
CAS 2444880-17-3C15H25ClN4O4
2-{1H,4H,5H,6H-Pyrrolo[3,4-c]pyrazol-1-yl}ethan-1-ol chemical structure, C7H11N3O, CAS 1824463-91-3
2-{1H,4H,5H,6H-Pyrrolo[3,4-c]pyrazol-1-yl}ethan-1-ol
CAS 1824463-91-3C7H11N3O
1-{2H,4H,5H,6H-Pyrrolo[3,4-c]pyrazol-5-yl}prop-2-en-1-one chemical structure, C8H9N3O, CAS 1933576-99-8
1-{2H,4H,5H,6H-Pyrrolo[3,4-c]pyrazol-5-yl}prop-2-en-1-one
CAS 1933576-99-8C8H9N3O
2-Amino-1-{1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-5-yl}ethan-1-one chemical structure, C7H10N4O, CAS 1935035-65-6
2-Amino-1-{1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-5-yl}ethan-1-one
CAS 1935035-65-6C7H10N4O