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Murcko scaffold

Morpholino[1-(phenylsulfonyl)-4-piperidinyl]methanone scaffold

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
9
With full pages
5
Scaffold SMILES

O=C(C1CCN(S(=O)(=O)c2ccccc2)CC1)N1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Morpholino[1-(phenylsulfonyl)-4-piperidinyl]methanone page
Murcko scaffold O=C(C1CCN(S(=O)(=O)c2ccccc2)CC1)N1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

Morpholino[1-(phenylsulfonyl)-4-piperidinyl]methanone chemical structure, C16H22N2O4S, CAS 478041-46-2
Morpholino[1-(phenylsulfonyl)-4-piperidinyl]methanone
CAS 478041-46-2C16H22N2O4S
{1-[(4-Methylphenyl)sulfonyl]-4-piperidinyl}(morpholino)methanone chemical structure, C17H24N2O4S, CAS 433941-29-8
{1-[(4-Methylphenyl)sulfonyl]-4-piperidinyl}(morpholino)methanone
CAS 433941-29-8C17H24N2O4S
[1-(4-Fluorophenyl)sulfonylpiperidin-4-yl]-morpholin-4-ylmethanone chemical structure, C16H21FN2O4S, CAS 591239-20-2
[1-(4-Fluorophenyl)sulfonylpiperidin-4-yl]-morpholin-4-ylmethanone
CAS 591239-20-2C16H21FN2O4S
[1-(3,4-Dimethoxyphenyl)sulfonylpiperidin-4-yl]-morpholin-4-ylmethanone chemical structure, C18H26N2O6S, CAS 591239-24-6
[1-(3,4-Dimethoxyphenyl)sulfonylpiperidin-4-yl]-morpholin-4-ylmethanone
CAS 591239-24-6C18H26N2O6S
[1-(4-Bromophenyl)sulfonylpiperidin-4-yl]-morpholin-4-ylmethanone chemical structure, C16H21BrN2O4S, CAS 768293-37-4
[1-(4-Bromophenyl)sulfonylpiperidin-4-yl]-morpholin-4-ylmethanone
CAS 768293-37-4C16H21BrN2O4S
(2,6-Dimethylmorpholino)[1-(phenylsulfonyl)-4-piperidinyl]methanone chemical structure, C18H26N2O4S, CAS 326871-46-9
(2,6-Dimethylmorpholino)[1-(phenylsulfonyl)-4-piperidinyl]methanone
CAS 326871-46-9C18H26N2O4S
(2,6-Dimethylmorpholin-4-yl)-[1-(4-methylphenyl)sulfonylpiperidin-4-yl]methanone chemical structure, C19H28N2O4S, CAS 879079-64-8
(2,6-Dimethylmorpholin-4-yl)-[1-(4-methylphenyl)sulfonylpiperidin-4-yl]methanone
CAS 879079-64-8C19H28N2O4S
{1-[(5-Fluoro-2-methoxyphenyl)sulfonyl]piperidin-4-yl}(morpholin-4-yl)methanone chemical structure, C17H23FN2O5S, CAS 947122-62-5
{1-[(5-Fluoro-2-methoxyphenyl)sulfonyl]piperidin-4-yl}(morpholin-4-yl)methanone
CAS 947122-62-5C17H23FN2O5S
4-[1-(4-Methylbenzenesulfonyl)piperidine-4-carbonyl]morpholine-3-carbonitrile chemical structure, C18H23N3O4S, CAS 1384565-93-8
4-[1-(4-Methylbenzenesulfonyl)piperidine-4-carbonyl]morpholine-3-carbonitrile
CAS 1384565-93-8C18H23N3O4S