CompoundList
Sign in
Murcko scaffold

1,4-Bis(phenylsulfonyl)piperazine scaffold

151 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
151
With full pages
19
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCN(S(=O)(=O)c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,4-Bis(phenylsulfonyl)piperazine page
Murcko scaffold O=S(=O)(c1ccccc1)N1CCN(S(=O)(=O)c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 151 chemicals

1,4-Bis(phenylsulfonyl)piperazine chemical structure, C16H18N2O4S2, CAS 7250-99-9
1,4-Bis(phenylsulfonyl)piperazine
CAS 7250-99-9C16H18N2O4S2
1,4-Bis-(2,5-dimethyl-benzenesulfonyl)-piperazine chemical structure, C20H26N2O4S2, CAS 6266-86-0
1,4-Bis-(2,5-dimethyl-benzenesulfonyl)-piperazine
CAS 6266-86-0C20H26N2O4S2
1,4-Ditosylpiperazine chemical structure, C18H22N2O4S2, CAS 17046-84-3
1,4-Ditosylpiperazine
CAS 17046-84-3C18H22N2O4S2
1,4-Bis[(4-fluorophenyl)sulfonyl]piperazine chemical structure, C16H16F2N2O4S2, CAS 6337-96-8
1,4-Bis[(4-fluorophenyl)sulfonyl]piperazine
CAS 6337-96-8C16H16F2N2O4S2
1,4-Bis[(4-bromophenyl)sulfonyl]piperazine chemical structure, C16H16Br2N2O4S2, CAS 107785-47-7
1,4-Bis[(4-bromophenyl)sulfonyl]piperazine
CAS 107785-47-7C16H16Br2N2O4S2
Piperazine, 1,4-bis[(3-nitrophenyl)sulfonyl]- chemical structure, C16H16N4O8S2, CAS 80303-91-9
Piperazine, 1,4-bis[(3-nitrophenyl)sulfonyl]-
CAS 80303-91-9C16H16N4O8S2
N-(4-((4-(Phenylsulfonyl)piperazin-1-yl)sulfonyl)phenyl)acetamide chemical structure, C18H21N3O5S2, CAS 428823-02-3
N-(4-((4-(Phenylsulfonyl)piperazin-1-yl)sulfonyl)phenyl)acetamide
CAS 428823-02-3C18H21N3O5S2
N-[4-[4-(4-Methylphenyl)sulfonylpiperazin-1-yl]sulfonylphenyl]acetamide chemical structure, C19H23N3O5S2, CAS 428851-03-0
N-[4-[4-(4-Methylphenyl)sulfonylpiperazin-1-yl]sulfonylphenyl]acetamide
CAS 428851-03-0C19H23N3O5S2
1,4-Bis[(4-ethoxyphenyl)sulfonyl]piperazine chemical structure, C20H26N2O6S2, CAS 326885-43-2
1,4-Bis[(4-ethoxyphenyl)sulfonyl]piperazine
CAS 326885-43-2C20H26N2O6S2
1,4-Bis[(4-methoxy-3-methylphenyl)sulfonyl]piperazine chemical structure, C20H26N2O6S2, CAS 457961-46-5
1,4-Bis[(4-methoxy-3-methylphenyl)sulfonyl]piperazine
CAS 457961-46-5C20H26N2O6S2
1,4-Bis[(2,4,6-trimethylphenyl)sulfonyl]piperazine chemical structure, C22H30N2O4S2, CAS 300816-18-6
1,4-Bis[(2,4,6-trimethylphenyl)sulfonyl]piperazine
CAS 300816-18-6C22H30N2O4S2
1-[(4-Chlorophenyl)sulfonyl]-4-(phenylsulfonyl)piperazine chemical structure, C16H17ClN2O4S2, CAS 423739-91-7
1-[(4-Chlorophenyl)sulfonyl]-4-(phenylsulfonyl)piperazine
CAS 423739-91-7C16H17ClN2O4S2
1,4-Bis[(4-methoxyphenyl)sulfonyl]piperazine chemical structure, C18H22N2O6S2, CAS 51983-30-3
1,4-Bis[(4-methoxyphenyl)sulfonyl]piperazine
CAS 51983-30-3C18H22N2O6S2
1,4-Bis[(3,4-dimethoxyphenyl)sulfonyl]piperazine chemical structure, C20H26N2O8S2, CAS 324776-62-7
1,4-Bis[(3,4-dimethoxyphenyl)sulfonyl]piperazine
CAS 324776-62-7C20H26N2O8S2
1,4-Bis(5-chloro-2-methoxybenzenesulfonyl)piperazine chemical structure, C18H20Cl2N2O6S2, CAS 332388-60-0
1,4-Bis(5-chloro-2-methoxybenzenesulfonyl)piperazine
CAS 332388-60-0C18H20Cl2N2O6S2
1,4-Bis[(2-methoxy-5-methylphenyl)sulfonyl]piperazine chemical structure, C20H26N2O6S2, CAS 332388-76-8
1,4-Bis[(2-methoxy-5-methylphenyl)sulfonyl]piperazine
CAS 332388-76-8C20H26N2O6S2
1-[(4-Methoxyphenyl)sulfonyl]-4-[(4-methylphenyl)sulfonyl]piperazine chemical structure, C18H22N2O5S2, CAS 333756-60-8
1-[(4-Methoxyphenyl)sulfonyl]-4-[(4-methylphenyl)sulfonyl]piperazine
CAS 333756-60-8C18H22N2O5S2
1-[(4-Chlorophenyl)sulfonyl]-4-[(4-methoxyphenyl)sulfonyl]piperazine chemical structure, C17H19ClN2O5S2, CAS 333757-17-8
1-[(4-Chlorophenyl)sulfonyl]-4-[(4-methoxyphenyl)sulfonyl]piperazine
CAS 333757-17-8C17H19ClN2O5S2
1-Benzenesulfonyl-4-(4-methoxy-benzenesulfonyl)-piperazine chemical structure, C17H20N2O5S2, CAS 333757-33-8
1-Benzenesulfonyl-4-(4-methoxy-benzenesulfonyl)-piperazine
CAS 333757-33-8C17H20N2O5S2
1-(4-Fluorophenyl)sulfonyl-4-(4-nitrophenyl)sulfonylpiperazine chemical structure, C16H16FN3O6S2, CAS 429623-01-8
1-(4-Fluorophenyl)sulfonyl-4-(4-nitrophenyl)sulfonylpiperazine
CAS 429623-01-8C16H16FN3O6S2
1-(Benzenesulfonyl)-4-(4-nitrophenyl)sulfonylpiperazine chemical structure, C16H17N3O6S2, CAS 428836-46-8
1-(Benzenesulfonyl)-4-(4-nitrophenyl)sulfonylpiperazine
CAS 428836-46-8C16H17N3O6S2
1-(4-Methylphenyl)sulfonyl-4-(4-nitrophenyl)sulfonylpiperazine chemical structure, C17H19N3O6S2, CAS 428848-07-1
1-(4-Methylphenyl)sulfonyl-4-(4-nitrophenyl)sulfonylpiperazine
CAS 428848-07-1C17H19N3O6S2
1-(4-Chlorophenyl)sulfonyl-4-(4-nitrophenyl)sulfonylpiperazine chemical structure, C16H16ClN3O6S2, CAS 429621-92-1
1-(4-Chlorophenyl)sulfonyl-4-(4-nitrophenyl)sulfonylpiperazine
CAS 429621-92-1C16H16ClN3O6S2
1-(4-Methoxyphenyl)sulfonyl-4-(4-nitrophenyl)sulfonylpiperazine chemical structure, C17H19N3O7S2, CAS 428850-50-4
1-(4-Methoxyphenyl)sulfonyl-4-(4-nitrophenyl)sulfonylpiperazine
CAS 428850-50-4C17H19N3O7S2