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Murcko scaffold

[4-(Benzenesulfonyl)piperazin-1-yl]-pyridin-3-ylmethanone scaffold

27 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 23
Chemicals: 27
With full pages: 11

Scaffold SMILES

O=C(c1cccnc1)N1CCN(S(=O)(=O)c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the [4-(Benzenesulfonyl)piperazin-1-yl]-pyridin-3-ylmethanone page

Murcko scaffold O=C(c1cccnc1)N1CCN(S(=O)(=O)c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

[4-(4-Fluorophenyl)sulfonylpiperazin-1-yl]-pyridin-3-ylmethanone chemical structure, C16H16FN3O3S, CAS 428828-24-4

[4-(4-Fluorophenyl)sulfonylpiperazin-1-yl]-pyridin-3-ylmethanone

CAS 428828-24-4C₁₆H₁₆FN₃O₃S

[4-(Benzenesulfonyl)piperazin-1-yl]-pyridin-3-ylmethanone chemical structure, C16H17N3O3S, CAS 333756-28-8

[4-(Benzenesulfonyl)piperazin-1-yl]-pyridin-3-ylmethanone

CAS 333756-28-8C₁₆H₁₇N₃O₃S

[4-(4-Methylphenyl)sulfonylpiperazin-1-yl]-pyridin-3-ylmethanone chemical structure, C17H19N3O3S, CAS 333757-01-0

[4-(4-Methylphenyl)sulfonylpiperazin-1-yl]-pyridin-3-ylmethanone

CAS 333757-01-0C₁₇H₁₉N₃O₃S

1-[(4-Chlorophenyl)sulfonyl]-4-(3-pyridinylcarbonyl)piperazine chemical structure, C16H16ClN3O3S, CAS 333755-98-9

1-[(4-Chlorophenyl)sulfonyl]-4-(3-pyridinylcarbonyl)piperazine

CAS 333755-98-9C₁₆H₁₆ClN₃O₃S

[4-(4-Methoxy-benzenesulfonyl)-piperazin-1-yl]-pyridin-3-yl-methanone chemical structure, C17H19N3O4S, CAS 333756-24-4

[4-(4-Methoxy-benzenesulfonyl)-piperazin-1-yl]-pyridin-3-yl-methanone

CAS 333756-24-4C₁₇H₁₉N₃O₄S

[4-(2-Nitrophenyl)sulfonylpiperazin-1-yl]-pyridin-3-ylmethanone chemical structure, C16H16N4O5S, CAS 488804-79-1

[4-(2-Nitrophenyl)sulfonylpiperazin-1-yl]-pyridin-3-ylmethanone

CAS 488804-79-1C₁₆H₁₆N₄O₅S

N-[4-[4-(Pyridine-3-carbonyl)piperazin-1-yl]sulfonylphenyl]acetamide chemical structure, C18H20N4O4S, CAS 428847-02-3

N-[4-[4-(Pyridine-3-carbonyl)piperazin-1-yl]sulfonylphenyl]acetamide

CAS 428847-02-3C₁₈H₂₀N₄O₄S

1-(Benzenesulfonyl)-4-[2-(methylsulfanyl)pyridine-3-carbonyl]piperazine chemical structure, C17H19N3O3S2, CAS 784159-09-7

1-(Benzenesulfonyl)-4-[2-(methylsulfanyl)pyridine-3-carbonyl]piperazine

CAS 784159-09-7C₁₇H₁₉N₃O₃S₂

1-(6-Chloropyridine-3-carbonyl)-4-(4-methylbenzenesulfonyl)piperazine chemical structure, C17H18ClN3O3S, CAS 748010-61-9

1-(6-Chloropyridine-3-carbonyl)-4-(4-methylbenzenesulfonyl)piperazine

CAS 748010-61-9C₁₇H₁₈ClN₃O₃S

1-(Benzenesulfonyl)-4-(6-chloropyridine-3-carbonyl)piperazine chemical structure, C16H16ClN3O3S, CAS 775313-70-7

1-(Benzenesulfonyl)-4-(6-chloropyridine-3-carbonyl)piperazine

CAS 775313-70-7C₁₆H₁₆ClN₃O₃S

[4-(3,4-Dimethoxyphenyl)sulfonylpiperazin-1-yl]-pyridin-3-ylmethanone chemical structure, C18H21N3O5S, CAS 830341-48-5

[4-(3,4-Dimethoxyphenyl)sulfonylpiperazin-1-yl]-pyridin-3-ylmethanone

CAS 830341-48-5C₁₈H₂₁N₃O₅S

1-(4-Chlorobenzenesulfonyl)-4-(6-chloropyridine-3-carbonyl)piperazine chemical structure, C16H15Cl2N3O3S, CAS 746634-98-0

1-(4-Chlorobenzenesulfonyl)-4-(6-chloropyridine-3-carbonyl)piperazine

CAS 746634-98-0C₁₆H₁₅Cl₂N₃O₃S

1-(4-Fluorobenzenesulfonyl)-4-[2-(methylsulfanyl)pyridine-3-carbonyl]piperazine chemical structure, C17H18FN3O3S2, CAS 848177-74-2

1-(4-Fluorobenzenesulfonyl)-4-[2-(methylsulfanyl)pyridine-3-carbonyl]piperazine

CAS 848177-74-2C₁₇H₁₈FN₃O₃S₂

1-(5,6-Dichloropyridine-3-carbonyl)-4-(4-fluorobenzenesulfonyl)piperazine chemical structure, C16H14Cl2FN3O3S, CAS 847793-18-4

1-(5,6-Dichloropyridine-3-carbonyl)-4-(4-fluorobenzenesulfonyl)piperazine

CAS 847793-18-4C₁₆H₁₄Cl₂FN₃O₃S

1-(4-Methylbenzenesulfonyl)-4-[2-(methylsulfanyl)pyridine-3-carbonyl]piperazine chemical structure, C18H21N3O3S2, CAS 880418-22-4

1-(4-Methylbenzenesulfonyl)-4-[2-(methylsulfanyl)pyridine-3-carbonyl]piperazine

CAS 880418-22-4C₁₈H₂₁N₃O₃S₂

(2-Chloropyridin-3-yl)-[4-(3,4-dimethylphenyl)sulfonylpiperazin-1-yl]methanone chemical structure, C18H20ClN3O3S, CAS 1111487-31-0

(2-Chloropyridin-3-yl)-[4-(3,4-dimethylphenyl)sulfonylpiperazin-1-yl]methanone

CAS 1111487-31-0C₁₈H₂₀ClN₃O₃S

1-(2,5-Dimethylbenzenesulfonyl)-4-[2-(methylsulfanyl)pyridine-3-carbonyl]piperazine chemical structure, C19H23N3O3S2, CAS 879773-35-0

1-(2,5-Dimethylbenzenesulfonyl)-4-[2-(methylsulfanyl)pyridine-3-carbonyl]piperazine

CAS 879773-35-0C₁₉H₂₃N₃O₃S₂

1-(2,3-Dichlorobenzenesulfonyl)-4-[2-(methylsulfanyl)pyridine-3-carbonyl]piperazine chemical structure, C17H17Cl2N3O3S2, CAS 880411-34-7

1-(2,3-Dichlorobenzenesulfonyl)-4-[2-(methylsulfanyl)pyridine-3-carbonyl]piperazine

CAS 880411-34-7C₁₇H₁₇Cl₂N₃O₃S₂

1-(4-Bromobenzenesulfonyl)-4-[2-(methylsulfanyl)pyridine-3-carbonyl]piperazine chemical structure, C17H18BrN3O3S2, CAS 941138-75-6

1-(4-Bromobenzenesulfonyl)-4-[2-(methylsulfanyl)pyridine-3-carbonyl]piperazine

CAS 941138-75-6C₁₇H₁₈BrN₃O₃S₂

4-({4-[2-(Methylsulfanyl)pyridine-3-carbonyl]piperazin-1-yl}sulfonyl)benzonitrile chemical structure, C18H18N4O3S2, CAS 941187-65-1

4-({4-[2-(Methylsulfanyl)pyridine-3-carbonyl]piperazin-1-yl}sulfonyl)benzonitrile

CAS 941187-65-1C₁₈H₁₈N₄O₃S₂

1-[4-Chloro-3-(trifluoromethyl)benzenesulfonyl]-4-(6-chloropyridine-3-carbonyl)piperazine chemical structure, C17H14Cl2F3N3O3S, CAS 1013261-91-0

1-[4-Chloro-3-(trifluoromethyl)benzenesulfonyl]-4-(6-chloropyridine-3-carbonyl)piperazine

CAS 1013261-91-0C₁₇H₁₄Cl₂F₃N₃O₃S

1-[2-(Methylsulfanyl)pyridine-3-carbonyl]-4-[4-(trifluoromethyl)benzenesulfonyl]piperazine chemical structure, C18H18F3N3O3S2, CAS 1030176-93-2

1-[2-(Methylsulfanyl)pyridine-3-carbonyl]-4-[4-(trifluoromethyl)benzenesulfonyl]piperazine

CAS 1030176-93-2C₁₈H₁₈F₃N₃O₃S₂

1-(2-Chloropyridine-3-carbonyl)-4-(3,4-dimethoxybenzenesulfonyl)piperazine chemical structure, C18H20ClN3O5S, CAS 1208679-35-9

1-(2-Chloropyridine-3-carbonyl)-4-(3,4-dimethoxybenzenesulfonyl)piperazine

CAS 1208679-35-9C₁₈H₂₀ClN₃O₅S

Cnv-2197944 chemical structure, C19H20F3N3O3S, CAS 1204535-44-3

CAS 1204535-44-3C₁₉H₂₀F₃N₃O₃S