CompoundList
Sign in
Murcko scaffold

Phenyl(4-(phenylmethyl)-1-piperazinyl)methanone scaffold

377 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
377
With full pages
72
Scaffold SMILES

O=C(c1ccccc1)N1CCN(Cc2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Phenyl(4-(phenylmethyl)-1-piperazinyl)methanone page
Murcko scaffold O=C(c1ccccc1)N1CCN(Cc2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 377 chemicals

Ketone, 4-(p-tert-butylbenzyl)piperazinyl 3,4,5-trimethoxyphenyl chemical structure, C25H34N2O4, CAS 17766-62-0
Ketone, 4-(p-tert-butylbenzyl)piperazinyl 3,4,5-trimethoxyphenyl
CAS 17766-62-0C25H34N2O4
Phenyl(4-(phenylmethyl)-1-piperazinyl)methanone chemical structure, C18H20N2O, CAS 63991-67-3
Phenyl(4-(phenylmethyl)-1-piperazinyl)methanone
CAS 63991-67-3C18H20N2O
(4-Benzyl-1-piperazinyl)(3,4,5-trimethoxyphenyl)methanone chemical structure, C21H26N2O4, CAS 48216-63-3
(4-Benzyl-1-piperazinyl)(3,4,5-trimethoxyphenyl)methanone
CAS 48216-63-3C21H26N2O4
1-Benzyl-4-(2-fluorobenzoyl)piperazine chemical structure, C18H19FN2O, CAS 326902-14-1
1-Benzyl-4-(2-fluorobenzoyl)piperazine
CAS 326902-14-1C18H19FN2O
1-(2-Chlorobenzyl)-4-(3-methoxybenzoyl)piperazine chemical structure, C19H21ClN2O2, CAS 425395-81-9
1-(2-Chlorobenzyl)-4-(3-methoxybenzoyl)piperazine
CAS 425395-81-9C19H21ClN2O2
[4-[(3-Chlorophenyl)methyl]piperazin-1-yl]-(2-fluorophenyl)methanone chemical structure, C18H18ClFN2O, CAS 462613-66-7
[4-[(3-Chlorophenyl)methyl]piperazin-1-yl]-(2-fluorophenyl)methanone
CAS 462613-66-7C18H18ClFN2O
(3-Methoxyphenyl)-[4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]methanone chemical structure, C20H21F3N2O2, CAS 355813-15-9
(3-Methoxyphenyl)-[4-[[2-(trifluoromethyl)phenyl]methyl]piperazin-1-yl]methanone
CAS 355813-15-9C20H21F3N2O2
[4-[(3-Fluorophenyl)methyl]piperazin-1-yl]-(3-methoxyphenyl)methanone chemical structure, C19H21FN2O2, CAS 461398-00-5
[4-[(3-Fluorophenyl)methyl]piperazin-1-yl]-(3-methoxyphenyl)methanone
CAS 461398-00-5C19H21FN2O2
(3,4-Dimethoxyphenyl)-[4-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]piperazin-1-yl]methanone chemical structure, C22H28N2O6, CAS 425389-95-3
(3,4-Dimethoxyphenyl)-[4-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]piperazin-1-yl]methanone
CAS 425389-95-3C22H28N2O6
(4-Benzylpiperazin-1-yl)-(4-chlorophenyl)methanone chemical structure, C18H19ClN2O, CAS 289475-98-5
(4-Benzylpiperazin-1-yl)-(4-chlorophenyl)methanone
CAS 289475-98-5C18H19ClN2O
4-Fluorophenyl 4-benzylpiperazinyl ketone chemical structure, C18H19FN2O, CAS 289475-97-4
4-Fluorophenyl 4-benzylpiperazinyl ketone
CAS 289475-97-4C18H19FN2O
1-Benzyl-4-(2,6-dichlorobenzoyl)piperazine chemical structure, C18H18Cl2N2O, CAS 334974-59-3
1-Benzyl-4-(2,6-dichlorobenzoyl)piperazine
CAS 334974-59-3C18H18Cl2N2O
(4-Benzylpiperazin-1-yl)-(2-ethoxyphenyl)methanone chemical structure, C20H24N2O2, CAS 314055-28-2
(4-Benzylpiperazin-1-yl)-(2-ethoxyphenyl)methanone
CAS 314055-28-2C20H24N2O2
(4-Benzylpiperazin-1-yl)(3-methoxyphenyl)methanone chemical structure, C19H22N2O2, CAS 113240-41-8
(4-Benzylpiperazin-1-yl)(3-methoxyphenyl)methanone
CAS 113240-41-8C19H22N2O2
1-Benzyl-4-(4-ethoxybenzoyl)piperazine chemical structure, C20H24N2O2, CAS 282104-30-7
1-Benzyl-4-(4-ethoxybenzoyl)piperazine
CAS 282104-30-7C20H24N2O2
(3-Fluorophenyl)[4-(3-nitrobenzyl)piperazin-1-yl]methanone chemical structure, C18H18FN3O3, CAS 355392-88-0
(3-Fluorophenyl)[4-(3-nitrobenzyl)piperazin-1-yl]methanone
CAS 355392-88-0C18H18FN3O3
(2-Fluorophenyl)[4-(3-nitrobenzyl)piperazin-1-yl]methanone chemical structure, C18H18FN3O3, CAS 355813-10-4
(2-Fluorophenyl)[4-(3-nitrobenzyl)piperazin-1-yl]methanone
CAS 355813-10-4C18H18FN3O3
(4-Methoxyphenyl)[4-(2-methylbenzyl)piperazin-1-yl]methanone chemical structure, C20H24N2O2, CAS 355814-15-2
(4-Methoxyphenyl)[4-(2-methylbenzyl)piperazin-1-yl]methanone
CAS 355814-15-2C20H24N2O2
(4-Fluorophenyl)-[4-[(2-nitrophenyl)methyl]piperazin-1-yl]methanone chemical structure, C18H18FN3O3, CAS 355815-15-5
(4-Fluorophenyl)-[4-[(2-nitrophenyl)methyl]piperazin-1-yl]methanone
CAS 355815-15-5C18H18FN3O3
(4-Fluorophenyl)-[4-[(3-nitrophenyl)methyl]piperazin-1-yl]methanone chemical structure, C18H18FN3O3, CAS 355815-34-8
(4-Fluorophenyl)-[4-[(3-nitrophenyl)methyl]piperazin-1-yl]methanone
CAS 355815-34-8C18H18FN3O3
[4-[(2-Methylphenyl)methyl]piperazin-1-yl]-(4-nitrophenyl)methanone chemical structure, C19H21N3O3, CAS 5934-81-6
[4-[(2-Methylphenyl)methyl]piperazin-1-yl]-(4-nitrophenyl)methanone
CAS 5934-81-6C19H21N3O3
1-(2-Methoxybenzoyl)-4-(2-methylbenzyl)piperazine chemical structure, C20H24N2O2, CAS 444907-06-6
1-(2-Methoxybenzoyl)-4-(2-methylbenzyl)piperazine
CAS 444907-06-6C20H24N2O2
(3-Methoxy-phenyl)-[4-(2-methyl-benzyl)-piperazin-1-yl]-methanone chemical structure, C20H24N2O2, CAS 5872-01-5
(3-Methoxy-phenyl)-[4-(2-methyl-benzyl)-piperazin-1-yl]-methanone
CAS 5872-01-5C20H24N2O2
[4-(3-Methoxybenzyl)piperazin-1-yl](phenyl)methanone chemical structure, C19H22N2O2, CAS 354536-07-5
[4-(3-Methoxybenzyl)piperazin-1-yl](phenyl)methanone
CAS 354536-07-5C19H22N2O2