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Murcko scaffold

Ring system with 2 rings and 13 atoms

97 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
97
With full pages
8
Scaffold SMILES

C(=Cc1cccs1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Cc1cccs1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 97 chemicals

1-[2,6-Dimethyl-4-[2-(2-thienyl)ethenyl]phenyl] butanedioate chemical structure, C18H18O4S, CAS 125722-33-0
1-[2,6-Dimethyl-4-[2-(2-thienyl)ethenyl]phenyl] butanedioate
CAS 125722-33-0C18H18O4S
2-Phenyl-3-thiophen-2-ylprop-2-enoic acid chemical structure, C13H10O2S
2-Phenyl-3-thiophen-2-ylprop-2-enoic acid
C13H10O2S
2-Phenyl-3-thiophen-2-yl-acrylic acid chemical structure, C13H10O2S, CAS 10569-35-4
2-Phenyl-3-thiophen-2-yl-acrylic acid
CAS 10569-35-4C13H10O2S
2-[2-(2-Thienyl)vinyl]benzoic acid chemical structure, C13H10O2S, CAS 1966-89-8
2-[2-(2-Thienyl)vinyl]benzoic acid
CAS 1966-89-8C13H10O2S
2-Phenyl-3-(2-thienyl)acrylonitrile chemical structure, C13H9NS, CAS 72030-16-1
2-Phenyl-3-(2-thienyl)acrylonitrile
CAS 72030-16-1C13H9NS
(E)-3-Phenyl-2-thiophen-2-ylprop-2-enenitrile chemical structure, C13H9NS, CAS 89986-24-3
(E)-3-Phenyl-2-thiophen-2-ylprop-2-enenitrile
CAS 89986-24-3C13H9NS
3-Phenyl-2-thien-2-ylacrylic acid chemical structure, C13H10O2S, CAS 38343-87-2
3-Phenyl-2-thien-2-ylacrylic acid
CAS 38343-87-2C13H10O2S
(2E)-3-Phenyl-2-thien-2-ylacrylic acid chemical structure, C13H10O2S, CAS 104314-03-6
(2E)-3-Phenyl-2-thien-2-ylacrylic acid
CAS 104314-03-6C13H10O2S
2-(4-Methylphenyl)-3-(5-methylthiophen-2-yl)prop-2-enenitrile chemical structure, C15H13NS, CAS 6285-63-8
2-(4-Methylphenyl)-3-(5-methylthiophen-2-yl)prop-2-enenitrile
CAS 6285-63-8C15H13NS
Thiophene, 2-(2-phenylethenyl)- chemical structure, C12H10S, CAS 3783-65-1
Thiophene, 2-(2-phenylethenyl)-
CAS 3783-65-1C12H10S
2-(5-Acetyl-2-thienyl)-3-phenylacrylonitrile chemical structure, C15H11NOS, CAS 1164488-99-6
2-(5-Acetyl-2-thienyl)-3-phenylacrylonitrile
CAS 1164488-99-6C15H11NOS
2-(5-Acetyl-2-thienyl)-3-(3-methoxyphenyl)acrylonitrile chemical structure, C16H13NO2S, CAS 1164544-45-9
2-(5-Acetyl-2-thienyl)-3-(3-methoxyphenyl)acrylonitrile
CAS 1164544-45-9C16H13NO2S
2-(5-Acetyl-2-thienyl)-3-(2,5-difluorophenyl)acrylonitrile chemical structure, C15H9F2NOS, CAS 478260-99-0
2-(5-Acetyl-2-thienyl)-3-(2,5-difluorophenyl)acrylonitrile
CAS 478260-99-0C15H9F2NOS
(E)-3-(5-Chlorothiophen-2-yl)-2-(4-nitrophenyl)prop-2-enenitrile chemical structure, C13H7ClN2O2S, CAS 675857-70-2
(E)-3-(5-Chlorothiophen-2-yl)-2-(4-nitrophenyl)prop-2-enenitrile
CAS 675857-70-2C13H7ClN2O2S
3-(4-Fluoro-phenyl)-2-thiophen-2-yl-acrylic acid chemical structure, C13H9FO2S, CAS 104314-04-7
3-(4-Fluoro-phenyl)-2-thiophen-2-yl-acrylic acid
CAS 104314-04-7C13H9FO2S
3-(4-Fluorophenyl)-2-(thiophen-2-yl)acrylic acid chemical structure, C13H9FO2S
3-(4-Fluorophenyl)-2-(thiophen-2-yl)acrylic acid
C13H9FO2S
Methyl 2-phenyl-3-thiophen-2-ylprop-2-enoate chemical structure, C14H12O2S
Methyl 2-phenyl-3-thiophen-2-ylprop-2-enoate
C14H12O2S
3-(4-Fluorophenyl)-2-thiophen-2-ylprop-2-enoic acid chemical structure, C13H9FO2S
3-(4-Fluorophenyl)-2-thiophen-2-ylprop-2-enoic acid
C13H9FO2S
2-Methyl-5-(2-phenylethenyl)thiophene chemical structure, C13H12S, CAS 36634-72-7
2-Methyl-5-(2-phenylethenyl)thiophene
CAS 36634-72-7C13H12S
alpha-(Phenylmethylene)-2-thiopheneacetonitrile chemical structure, C13H9NS, CAS 37033-97-9
alpha-(Phenylmethylene)-2-thiopheneacetonitrile
CAS 37033-97-9C13H9NS
3-(4-Methoxyphenyl)-2-thiophen-2-ylprop-2-enoic acid chemical structure, C14H12O3S
3-(4-Methoxyphenyl)-2-thiophen-2-ylprop-2-enoic acid
C14H12O3S
3-(3-Chlorophenyl)-2-thiophen-2-ylprop-2-enoic acid chemical structure, C13H9ClO2S
3-(3-Chlorophenyl)-2-thiophen-2-ylprop-2-enoic acid
C13H9ClO2S
3-(4-Bromophenyl)-2-(thiophen-2-yl)prop-2-enoic acid chemical structure, C13H9BrO2S, CAS 37094-46-5
3-(4-Bromophenyl)-2-(thiophen-2-yl)prop-2-enoic acid
CAS 37094-46-5C13H9BrO2S
alpha-[2-Thienyl]-p-[3,4-dichlorophenyl]acrylonitrile chemical structure, C13H7Cl2NS, CAS 37034-00-7
alpha-[2-Thienyl]-p-[3,4-dichlorophenyl]acrylonitrile
CAS 37034-00-7C13H7Cl2NS