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Murcko scaffold

Ring system with 2 rings and 13 atoms

230 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 13
Chemicals: 230
With full pages: 38

Scaffold SMILES

S=C1NC=CC(c2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold S=C1NC=CC(c2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 230 chemicals

Ethyl (R)-6-methyl-4-(3-nitrophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C14H15N3O4S, CAS 914915-59-6

Ethyl (R)-6-methyl-4-(3-nitrophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 914915-59-6C₁₄H₁₅N₃O₄S

Monastrol chemical structure, C14H16N2O3S, CAS 254753-54-3

CAS 254753-54-3C₁₄H₁₆N₂O₃S

(R)-Monastrol chemical structure, C14H16N2O3S, CAS 268739-54-4

CAS 268739-54-4C₁₄H₁₆N₂O₃S

Methyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C13H14N2O2S, CAS 126827-25-6

Methyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 126827-25-6C₁₃H₁₄N₂O₂S

Ethyl 6-(2-chloro-6-fluorophenyl)-2-mercapto-4-methyl-1,6-dihydropyrimidine-5-carboxylate chemical structure, C14H14ClFN2O2S, CAS 134074-31-0

Ethyl 6-(2-chloro-6-fluorophenyl)-2-mercapto-4-methyl-1,6-dihydropyrimidine-5-carboxylate

CAS 134074-31-0C₁₄H₁₄ClFN₂O₂S

Ethyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C14H16N2O2S, CAS 33458-26-3

Ethyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 33458-26-3C₁₄H₁₆N₂O₂S

Propyl 6-methyl-4-phenyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate chemical structure, C15H18N2O2S, CAS 681459-91-6

Propyl 6-methyl-4-phenyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate

CAS 681459-91-6C₁₅H₁₈N₂O₂S

Propan-2-yl 4-methyl-6-phenyl-2-sulfanyl-1,6-dihydropyrimidine-5-carboxylate chemical structure, C15H18N2O2S, CAS 321691-00-3

Propan-2-yl 4-methyl-6-phenyl-2-sulfanyl-1,6-dihydropyrimidine-5-carboxylate

CAS 321691-00-3C₁₅H₁₈N₂O₂S

Methyl 6-methyl-4-(3-nitrophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C13H13N3O4S, CAS 134074-33-2

Methyl 6-methyl-4-(3-nitrophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 134074-33-2C₁₃H₁₃N₃O₄S

Propyl 6-methyl-4-(3-nitrophenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate chemical structure, C15H17N3O4S, CAS 681459-92-7

Propyl 6-methyl-4-(3-nitrophenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate

CAS 681459-92-7C₁₅H₁₇N₃O₄S

2-Methylpropyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C16H20N2O2S, CAS 608492-37-1

2-Methylpropyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 608492-37-1C₁₆H₂₀N₂O₂S

Isopropyl 6-methyl-4-(3-nitrophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C15H17N3O4S, CAS 301233-27-2

Isopropyl 6-methyl-4-(3-nitrophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 301233-27-2C₁₅H₁₇N₃O₄S

Propan-2-yl 6-methyl-4-(4-nitrophenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate chemical structure, C15H17N3O4S, CAS 446269-05-2

Propan-2-yl 6-methyl-4-(4-nitrophenyl)-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate

CAS 446269-05-2C₁₅H₁₇N₃O₄S

Ethyl 4-(4-ethoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate chemical structure, C16H20N2O3S, CAS 293764-13-3

Ethyl 4-(4-ethoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

CAS 293764-13-3C₁₆H₂₀N₂O₃S

Ethyl 4-(4-fluorophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C14H15FN2O2S, CAS 201287-93-6

Ethyl 4-(4-fluorophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 201287-93-6C₁₄H₁₅FN₂O₂S

Ethyl 3-acetyl-1,6-dimethyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate chemical structure, C17H20N2O3S, CAS 123043-93-6

Ethyl 3-acetyl-1,6-dimethyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

CAS 123043-93-6C₁₇H₂₀N₂O₃S

Ethyl 3-acetyl-6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate chemical structure, C16H18N2O3S, CAS 111535-64-9

Ethyl 3-acetyl-6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

CAS 111535-64-9C₁₆H₁₈N₂O₃S

Ethyl 3-formyl-6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C15H16N2O3S, CAS 123044-10-0

Ethyl 3-formyl-6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 123044-10-0C₁₅H₁₆N₂O₃S

Ethyl 3-formyl-1,6-dimethyl-4-phenyl-2-sulfanylidene-4H-pyrimidine-5-carboxylate chemical structure, C16H18N2O3S, CAS 123044-11-1

Ethyl 3-formyl-1,6-dimethyl-4-phenyl-2-sulfanylidene-4H-pyrimidine-5-carboxylate

CAS 123044-11-1C₁₆H₁₈N₂O₃S

Ethyl 1,6-dimethyl-4-phenyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C15H18N2O2S, CAS 108958-81-2

Ethyl 1,6-dimethyl-4-phenyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 108958-81-2C₁₅H₁₈N₂O₂S

Ethyl 4-(4-hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C14H16N2O3S, CAS 203118-28-9

Ethyl 4-(4-hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 203118-28-9C₁₄H₁₆N₂O₃S

Ethyl 6-methyl-4-(3-nitrophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C14H15N3O4S, CAS 106720-50-7

Ethyl 6-methyl-4-(3-nitrophenyl)-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 106720-50-7C₁₄H₁₅N₃O₄S

Ethyl 4-(3-bromophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C14H15BrN2O2S, CAS 294854-53-8

Ethyl 4-(3-bromophenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 294854-53-8C₁₄H₁₅BrN₂O₂S

Methyl 4-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate chemical structure, C14H16N2O3S, CAS 134074-38-7

Methyl 4-(4-methoxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate

CAS 134074-38-7C₁₄H₁₆N₂O₃S