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Murcko scaffold

Ring system with 2 rings and 20 atoms

299 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
20
Chemicals
299
With full pages
8
Scaffold SMILES

O=C(COC(=O)c1ccccc1)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COC(=O)c1ccccc1)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 299 chemicals

[2-(Benzylamino)-2-oxoethyl] 3-chlorobenzoate chemical structure, C16H14ClNO3, CAS 446299-26-9
[2-(Benzylamino)-2-oxoethyl] 3-chlorobenzoate
CAS 446299-26-9C16H14ClNO3
[2-[(3,4-Dimethoxyphenyl)methylamino]-2-oxoethyl] 4-formylbenzoate chemical structure, C19H19NO6, CAS 474667-46-4
[2-[(3,4-Dimethoxyphenyl)methylamino]-2-oxoethyl] 4-formylbenzoate
CAS 474667-46-4C19H19NO6
{[(4-Fluorophenyl)methyl]carbamoyl}methyl 3,4,5-trimethoxybenzoate chemical structure, C19H20FNO6, CAS 380553-47-9
{[(4-Fluorophenyl)methyl]carbamoyl}methyl 3,4,5-trimethoxybenzoate
CAS 380553-47-9C19H20FNO6
[2-[(4-Chlorophenyl)methylamino]-2-oxoethyl] 4-formylbenzoate chemical structure, C17H14ClNO4, CAS 480395-32-2
[2-[(4-Chlorophenyl)methylamino]-2-oxoethyl] 4-formylbenzoate
CAS 480395-32-2C17H14ClNO4
[2-[Benzyl(methyl)amino]-2-oxoethyl] 2-amino-4-chlorobenzoate chemical structure, C17H17ClN2O3, CAS 722488-84-8
[2-[Benzyl(methyl)amino]-2-oxoethyl] 2-amino-4-chlorobenzoate
CAS 722488-84-8C17H17ClN2O3
[2-[(2-Chlorophenyl)methylamino]-2-oxoethyl] 2-hydroxybenzoate chemical structure, C16H14ClNO4, CAS 387835-86-1
[2-[(2-Chlorophenyl)methylamino]-2-oxoethyl] 2-hydroxybenzoate
CAS 387835-86-1C16H14ClNO4
[2-[(4-Methoxycarbonylphenyl)methylamino]-2-oxoethyl] 5-chloro-2-hydroxybenzoate chemical structure, C18H16ClNO6, CAS 750621-61-5
[2-[(4-Methoxycarbonylphenyl)methylamino]-2-oxoethyl] 5-chloro-2-hydroxybenzoate
CAS 750621-61-5C18H16ClNO6
[2-[(4-Methylphenyl)methylamino]-2-oxoethyl] 3,4,5-trimethoxybenzoate chemical structure, C20H23NO6, CAS 1002683-81-9
[2-[(4-Methylphenyl)methylamino]-2-oxoethyl] 3,4,5-trimethoxybenzoate
CAS 1002683-81-9C20H23NO6
{[(2-Chlorophenyl)methyl]carbamoyl}methyl 3,4,5-trimethoxybenzoate chemical structure, C19H20ClNO6, CAS 386262-40-4
{[(2-Chlorophenyl)methyl]carbamoyl}methyl 3,4,5-trimethoxybenzoate
CAS 386262-40-4C19H20ClNO6
[2-(Benzylamino)-2-oxoethyl] 3,4,5-trimethoxybenzoate chemical structure, C19H21NO6, CAS 446299-37-2
[2-(Benzylamino)-2-oxoethyl] 3,4,5-trimethoxybenzoate
CAS 446299-37-2C19H21NO6
[2-[(4-Methoxyphenyl)methylamino]-2-oxoethyl] 3,4,5-trimethoxybenzoate chemical structure, C20H23NO7, CAS 565190-14-9
[2-[(4-Methoxyphenyl)methylamino]-2-oxoethyl] 3,4,5-trimethoxybenzoate
CAS 565190-14-9C20H23NO7
[(1-Phenylethyl)carbamoyl]methyl 3-chlorobenzoate chemical structure, C17H16ClNO3, CAS 730255-63-7
[(1-Phenylethyl)carbamoyl]methyl 3-chlorobenzoate
CAS 730255-63-7C17H16ClNO3
[2-[Benzyl(propan-2-yl)amino]-2-oxoethyl] 3,4-dimethylbenzoate chemical structure, C21H25NO3, CAS 736978-12-4
[2-[Benzyl(propan-2-yl)amino]-2-oxoethyl] 3,4-dimethylbenzoate
CAS 736978-12-4C21H25NO3
[1-[(4-Methoxyphenyl)methylamino]-1-oxopropan-2-yl] 3-(dimethylamino)benzoate chemical structure, C20H24N2O4, CAS 746645-40-9
[1-[(4-Methoxyphenyl)methylamino]-1-oxopropan-2-yl] 3-(dimethylamino)benzoate
CAS 746645-40-9C20H24N2O4
2-Oxo-2-((1-phenylethyl)amino)ethyl 4-cyanobenzoate chemical structure, C18H16N2O3, CAS 380484-51-5
2-Oxo-2-((1-phenylethyl)amino)ethyl 4-cyanobenzoate
CAS 380484-51-5C18H16N2O3
[2-Oxo-2-(1-phenylethylamino)ethyl] 3,4-dimethylbenzoate chemical structure, C19H21NO3, CAS 848597-59-1
[2-Oxo-2-(1-phenylethylamino)ethyl] 3,4-dimethylbenzoate
CAS 848597-59-1C19H21NO3
[(1-Phenylethyl)carbamoyl]methyl 4-tert-butylbenzoate chemical structure, C21H25NO3, CAS 848291-74-7
[(1-Phenylethyl)carbamoyl]methyl 4-tert-butylbenzoate
CAS 848291-74-7C21H25NO3
[2-Oxo-2-(1-phenylethylamino)ethyl] 4-formylbenzoate chemical structure, C18H17NO4, CAS 746616-15-9
[2-Oxo-2-(1-phenylethylamino)ethyl] 4-formylbenzoate
CAS 746616-15-9C18H17NO4
[(1-Phenylethyl)carbamoyl]methyl 3,4-dichlorobenzoate chemical structure, C17H15Cl2NO3, CAS 730256-24-3
[(1-Phenylethyl)carbamoyl]methyl 3,4-dichlorobenzoate
CAS 730256-24-3C17H15Cl2NO3
[2-Oxo-2-(1-phenylethylamino)ethyl] 4-methylbenzoate chemical structure, C18H19NO3, CAS 904200-53-9
[2-Oxo-2-(1-phenylethylamino)ethyl] 4-methylbenzoate
CAS 904200-53-9C18H19NO3
2-Oxo-2-((1-phenylethyl)amino)ethyl 2-methylbenzoate chemical structure, C18H19NO3, CAS 876528-09-5
2-Oxo-2-((1-phenylethyl)amino)ethyl 2-methylbenzoate
CAS 876528-09-5C18H19NO3
2-[[(2-Methoxyphenyl)methyl]amino]-2-oxoethyl 3-[(diethylamino)sulfonyl]benzoate chemical structure, C21H26N2O6S, CAS 1004644-37-4
2-[[(2-Methoxyphenyl)methyl]amino]-2-oxoethyl 3-[(diethylamino)sulfonyl]benzoate
CAS 1004644-37-4C21H26N2O6S
[2-[(3-Chlorophenyl)methylamino]-2-oxoethyl] 3-cyanobenzoate chemical structure, C17H13ClN2O3, CAS 1002543-74-9
[2-[(3-Chlorophenyl)methylamino]-2-oxoethyl] 3-cyanobenzoate
CAS 1002543-74-9C17H13ClN2O3
2-((3-Chlorobenzyl)amino)-2-oxoethyl 2-chlorobenzoate chemical structure, C16H13Cl2NO3, CAS 1002419-08-0
2-((3-Chlorobenzyl)amino)-2-oxoethyl 2-chlorobenzoate
CAS 1002419-08-0C16H13Cl2NO3