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Murcko scaffold

Ring system with 2 rings and 18 atoms

8 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
8
With full pages
4
Scaffold SMILES

O=C(NN=CC=Cc1ccccc1)c1cc[nH]n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=CC=Cc1ccccc1)c1cc[nH]n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

3-Isopropyl-N'-(3-phenyl-2-propenylidene)-1H-pyrazole-5-carbohydrazide chemical structure, C16H18N4O, CAS 307975-75-3
3-Isopropyl-N'-(3-phenyl-2-propenylidene)-1H-pyrazole-5-carbohydrazide
CAS 307975-75-3C16H18N4O
(E)-3-(tert-Butyl)-N'-((E)-3-phenylallylidene)-1H-pyrazole-5-carbohydrazide chemical structure, C17H20N4O, CAS 1285640-91-6
(E)-3-(tert-Butyl)-N'-((E)-3-phenylallylidene)-1H-pyrazole-5-carbohydrazide
CAS 1285640-91-6C17H20N4O
(E)-N'-((Z)-2-Bromo-3-phenylallylidene)-3-methyl-1H-pyrazole-5-carbohydrazide chemical structure, C14H13BrN4O, CAS 306301-18-8
(E)-N'-((Z)-2-Bromo-3-phenylallylidene)-3-methyl-1H-pyrazole-5-carbohydrazide
CAS 306301-18-8C14H13BrN4O
5-Methyl-N-[(E)-[(E)-3-phenylprop-2-enylidene]amino]-1H-pyrazole-3-carboxamide chemical structure, C14H14N4O, CAS 306301-17-7
5-Methyl-N-[(E)-[(E)-3-phenylprop-2-enylidene]amino]-1H-pyrazole-3-carboxamide
CAS 306301-17-7C14H14N4O
(Z)-3-(tert-Butyl)-N'-((E)-3-(2-methoxyphenyl)allylidene)-1H-pyrazole-5-carbohydrazide chemical structure, C18H22N4O2, CAS 1284268-42-3
(Z)-3-(tert-Butyl)-N'-((E)-3-(2-methoxyphenyl)allylidene)-1H-pyrazole-5-carbohydrazide
CAS 1284268-42-3C18H22N4O2
3-tert-Butyl-N'-[(1Z,2E)-3-(2-methoxyphenyl)prop-2-en-1-ylidene]-1H-pyrazole-5-carbohydrazide chemical structure, C18H22N4O2
3-tert-Butyl-N'-[(1Z,2E)-3-(2-methoxyphenyl)prop-2-en-1-ylidene]-1H-pyrazole-5-carbohydrazide
C18H22N4O2
5-Methyl-N-[(E)-[(E)-3-(3-nitrophenyl)prop-2-enylidene]amino]-1H-pyrazole-3-carboxamide chemical structure, C14H13N5O3, CAS 1305339-22-3
5-Methyl-N-[(E)-[(E)-3-(3-nitrophenyl)prop-2-enylidene]amino]-1H-pyrazole-3-carboxamide
CAS 1305339-22-3C14H13N5O3
N'-[(1E,2E)-2-Methyl-3-phenylprop-2-en-1-ylidene]-3-(propan-2-yl)-1H-pyrazole-5-carbohydrazide chemical structure, C17H20N4O, CAS 1165796-37-1
N'-[(1E,2E)-2-Methyl-3-phenylprop-2-en-1-ylidene]-3-(propan-2-yl)-1H-pyrazole-5-carbohydrazide
CAS 1165796-37-1C17H20N4O