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Murcko scaffold

Ring system with 2 rings and 15 atoms

142 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
142
With full pages
4
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCCOC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)N1CCCOC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 142 chemicals

N'-{[3-(4-Chlorobenzenesulfonyl)-1,3-oxazinan-2-yl]methyl}-N-[2-(dimethylamino)ethyl]ethanediamide chemical structure, C17H25ClN4O5S, CAS 872987-19-4
N'-{[3-(4-Chlorobenzenesulfonyl)-1,3-oxazinan-2-yl]methyl}-N-[2-(dimethylamino)ethyl]ethanediamide
CAS 872987-19-4C17H25ClN4O5S
N1-(2-(dimethylamino)ethyl)-N2-((3-((2,5-dimethylphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide chemical structure, C19H30N4O5S, CAS 872724-24-8
N1-(2-(dimethylamino)ethyl)-N2-((3-((2,5-dimethylphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
CAS 872724-24-8C19H30N4O5S
N1-(2-(dimethylamino)ethyl)-N2-((3-((4-fluoro-3-methylphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide chemical structure, C18H27FN4O5S, CAS 872724-73-7
N1-(2-(dimethylamino)ethyl)-N2-((3-((4-fluoro-3-methylphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
CAS 872724-73-7C18H27FN4O5S
N-(2-Hydroxyethyl)-N'-{[3-(4-methoxybenzenesulfonyl)-1,3-oxazinan-2-yl]methyl}ethanediamide chemical structure, C16H23N3O7S, CAS 869071-53-4
N-(2-Hydroxyethyl)-N'-{[3-(4-methoxybenzenesulfonyl)-1,3-oxazinan-2-yl]methyl}ethanediamide
CAS 869071-53-4C16H23N3O7S
N1-((3-((4-methoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-methyloxalamide chemical structure, C15H21N3O6S, CAS 869071-59-0
N1-((3-((4-methoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-methyloxalamide
CAS 869071-59-0C15H21N3O6S
N1-((3-((4-methoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-propyloxalamide chemical structure, C17H25N3O6S, CAS 872862-86-7
N1-((3-((4-methoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-propyloxalamide
CAS 872862-86-7C17H25N3O6S
N1-isopentyl-N2-((3-((4-methoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide chemical structure, C19H29N3O6S, CAS 872862-88-9
N1-isopentyl-N2-((3-((4-methoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
CAS 872862-88-9C19H29N3O6S
N1-butyl-N2-((3-((4-methoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide chemical structure, C18H27N3O6S, CAS 872862-91-4
N1-butyl-N2-((3-((4-methoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
CAS 872862-91-4C18H27N3O6S
N1-(2-methoxyethyl)-N2-((3-((4-methoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide chemical structure, C17H25N3O7S, CAS 872862-92-5
N1-(2-methoxyethyl)-N2-((3-((4-methoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
CAS 872862-92-5C17H25N3O7S
N1-ethyl-N2-((3-((4-methoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide chemical structure, C16H23N3O6S, CAS 872880-85-8
N1-ethyl-N2-((3-((4-methoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
CAS 872880-85-8C16H23N3O6S
N1-isopropyl-N2-((3-((4-methoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide chemical structure, C17H25N3O6S, CAS 872880-86-9
N1-isopropyl-N2-((3-((4-methoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
CAS 872880-86-9C17H25N3O6S
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-propyloxalamide chemical structure, C18H27N3O7S, CAS 872976-18-6
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-propyloxalamide
CAS 872976-18-6C18H27N3O7S
N1-allyl-N2-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide chemical structure, C18H25N3O7S, CAS 872976-19-7
N1-allyl-N2-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
CAS 872976-19-7C18H25N3O7S
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-isopentyloxalamide chemical structure, C20H31N3O7S, CAS 872976-21-1
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-isopentyloxalamide
CAS 872976-21-1C20H31N3O7S
N1-butyl-N2-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide chemical structure, C19H29N3O7S, CAS 872976-24-4
N1-butyl-N2-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)oxalamide
CAS 872976-24-4C19H29N3O7S
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(2-methoxyethyl)oxalamide chemical structure, C18H27N3O8S, CAS 872976-25-5
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(2-methoxyethyl)oxalamide
CAS 872976-25-5C18H27N3O8S
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(2-hydroxyethyl)oxalamide chemical structure, C17H25N3O8S, CAS 872976-27-7
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-(2-hydroxyethyl)oxalamide
CAS 872976-27-7C17H25N3O8S
N'-{[3-(3,4-Dimethoxybenzenesulfonyl)-1,3-oxazinan-2-yl]methyl}-N-(3-hydroxypropyl)ethanediamide chemical structure, C18H27N3O8S, CAS 872976-28-8
N'-{[3-(3,4-Dimethoxybenzenesulfonyl)-1,3-oxazinan-2-yl]methyl}-N-(3-hydroxypropyl)ethanediamide
CAS 872976-28-8C18H27N3O8S
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-methyloxalamide chemical structure, C16H23N3O7S, CAS 872976-41-5
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-methyloxalamide
CAS 872976-41-5C16H23N3O7S
N'-{[3-(3,4-Dimethoxybenzenesulfonyl)-1,3-oxazinan-2-yl]methyl}-N-ethylethanediamide chemical structure, C17H25N3O7S, CAS 872976-42-6
N'-{[3-(3,4-Dimethoxybenzenesulfonyl)-1,3-oxazinan-2-yl]methyl}-N-ethylethanediamide
CAS 872976-42-6C17H25N3O7S
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-isopropyloxalamide chemical structure, C18H27N3O7S, CAS 872976-43-7
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-isopropyloxalamide
CAS 872976-43-7C18H27N3O7S
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-isobutyloxalamide chemical structure, C19H29N3O7S, CAS 872976-45-9
N1-((3-((3,4-dimethoxyphenyl)sulfonyl)-1,3-oxazinan-2-yl)methyl)-N2-isobutyloxalamide
CAS 872976-45-9C19H29N3O7S
N'-{[3-(4-Methoxy-3-methylbenzenesulfonyl)-1,3-oxazinan-2-yl]methyl}-N-propylethanediamide chemical structure, C18H27N3O6S, CAS 872985-92-7
N'-{[3-(4-Methoxy-3-methylbenzenesulfonyl)-1,3-oxazinan-2-yl]methyl}-N-propylethanediamide
CAS 872985-92-7C18H27N3O6S
N'-{[3-(4-Methoxy-3-methylbenzenesulfonyl)-1,3-oxazinan-2-yl]methyl}-N-(3-methylbutyl)ethanediamide chemical structure, C20H31N3O6S, CAS 872985-96-1
N'-{[3-(4-Methoxy-3-methylbenzenesulfonyl)-1,3-oxazinan-2-yl]methyl}-N-(3-methylbutyl)ethanediamide
CAS 872985-96-1C20H31N3O6S