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Murcko scaffold

Ring system with 3 rings and 21 atoms

42 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
42
With full pages
3
Scaffold SMILES

O=C(C=Cc1cccc2ccccc12)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1cccc2ccccc12)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

(E)-N-(2-Methoxy-5-nitrophenyl)-3-naphthalen-1-ylprop-2-enamide chemical structure, C20H16N2O4, CAS 356100-42-0
(E)-N-(2-Methoxy-5-nitrophenyl)-3-naphthalen-1-ylprop-2-enamide
CAS 356100-42-0C20H16N2O4
(E)-N-(3-Methoxyphenyl)-3-naphthalen-1-ylprop-2-enamide chemical structure, C20H17NO2, CAS 356100-52-2
(E)-N-(3-Methoxyphenyl)-3-naphthalen-1-ylprop-2-enamide
CAS 356100-52-2C20H17NO2
3-(1-Naphthyl)-N-phenylacrylamide chemical structure, C19H15NO, CAS 1776071-77-2
3-(1-Naphthyl)-N-phenylacrylamide
CAS 1776071-77-2C19H15NO
N-(3-Acetylphenyl)-3-(1-naphthyl)acrylamide chemical structure, C21H17NO2, CAS 328026-63-7
N-(3-Acetylphenyl)-3-(1-naphthyl)acrylamide
CAS 328026-63-7C21H17NO2
N-(4-Ethoxyphenyl)-3-(1-naphthyl)acrylamide chemical structure, C21H19NO2, CAS 327065-01-0
N-(4-Ethoxyphenyl)-3-(1-naphthyl)acrylamide
CAS 327065-01-0C21H19NO2
N-[4-(Acetylamino)phenyl]-3-(1-naphthyl)acrylamide chemical structure, C21H18N2O2, CAS 328026-61-5
N-[4-(Acetylamino)phenyl]-3-(1-naphthyl)acrylamide
CAS 328026-61-5C21H18N2O2
N-(4-Fluorophenyl)-3-(1-naphthyl)acrylamide chemical structure, C19H14FNO, CAS 327064-92-6
N-(4-Fluorophenyl)-3-(1-naphthyl)acrylamide
CAS 327064-92-6C19H14FNO
Methyl 4-[[(E)-3-naphthalen-1-ylprop-2-enoyl]amino]benzoate chemical structure, C21H17NO3, CAS 328026-74-0
Methyl 4-[[(E)-3-naphthalen-1-ylprop-2-enoyl]amino]benzoate
CAS 328026-74-0C21H17NO3
(E)-N-(2-Methyl-3-nitrophenyl)-3-naphthalen-1-ylprop-2-enamide chemical structure, C20H16N2O3, CAS 327068-66-6
(E)-N-(2-Methyl-3-nitrophenyl)-3-naphthalen-1-ylprop-2-enamide
CAS 327068-66-6C20H16N2O3
(E)-N-(2-Methyl-5-nitrophenyl)-3-naphthalen-1-ylprop-2-enamide chemical structure, C20H16N2O3, CAS 356100-41-9
(E)-N-(2-Methyl-5-nitrophenyl)-3-naphthalen-1-ylprop-2-enamide
CAS 356100-41-9C20H16N2O3
(E)-N-(3,4-Dichlorophenyl)-3-naphthalen-1-ylprop-2-enamide chemical structure, C19H13Cl2NO, CAS 356100-40-8
(E)-N-(3,4-Dichlorophenyl)-3-naphthalen-1-ylprop-2-enamide
CAS 356100-40-8C19H13Cl2NO
Ethyl 4-[[(E)-3-naphthalen-1-ylprop-2-enoyl]amino]benzoate chemical structure, C22H19NO3, CAS 327068-58-6
Ethyl 4-[[(E)-3-naphthalen-1-ylprop-2-enoyl]amino]benzoate
CAS 327068-58-6C22H19NO3
(E)-3-Naphthalen-1-yl-N-(3-nitrophenyl)prop-2-enamide chemical structure, C19H14N2O3, CAS 356100-30-6
(E)-3-Naphthalen-1-yl-N-(3-nitrophenyl)prop-2-enamide
CAS 356100-30-6C19H14N2O3
N-(4-Methylphenyl)-3-(1-naphthyl)acrylamide chemical structure, C20H17NO, CAS 328026-83-1
N-(4-Methylphenyl)-3-(1-naphthyl)acrylamide
CAS 328026-83-1C20H17NO
N-(3,4-Dimethylphenyl)-3-naphthalen-1-ylprop-2-enamide chemical structure, C21H19NO
N-(3,4-Dimethylphenyl)-3-naphthalen-1-ylprop-2-enamide
C21H19NO
(Z)-2-Cyano-N-(4-hydroxyphenyl)-3-naphthalen-1-ylprop-2-enamide chemical structure, C20H14N2O2, CAS 5734-65-6
(Z)-2-Cyano-N-(4-hydroxyphenyl)-3-naphthalen-1-ylprop-2-enamide
CAS 5734-65-6C20H14N2O2
(E)-N-(4-Chloro-3-nitrophenyl)-3-naphthalen-1-ylprop-2-enamide chemical structure, C19H13ClN2O3, CAS 356100-36-2
(E)-N-(4-Chloro-3-nitrophenyl)-3-naphthalen-1-ylprop-2-enamide
CAS 356100-36-2C19H13ClN2O3
(E)-N-[4-(Diethylsulfamoyl)phenyl]-3-naphthalen-1-ylprop-2-enamide chemical structure, C23H24N2O3S, CAS 356100-63-5
(E)-N-[4-(Diethylsulfamoyl)phenyl]-3-naphthalen-1-ylprop-2-enamide
CAS 356100-63-5C23H24N2O3S
(Z)-N-(3,4-Dimethylphenyl)-3-naphthalen-1-ylprop-2-enamide chemical structure, C21H19NO
(Z)-N-(3,4-Dimethylphenyl)-3-naphthalen-1-ylprop-2-enamide
C21H19NO
Ethyl 4-((2E)-2-cyano-3-naphthylprop-2-enoylamino)benzoate chemical structure, C23H18N2O3, CAS 364626-11-9
Ethyl 4-((2E)-2-cyano-3-naphthylprop-2-enoylamino)benzoate
CAS 364626-11-9C23H18N2O3
(E)-2-Cyano-N-(2-methylphenyl)-3-naphthalen-1-ylprop-2-enamide chemical structure, C21H16N2O, CAS 345258-21-1
(E)-2-Cyano-N-(2-methylphenyl)-3-naphthalen-1-ylprop-2-enamide
CAS 345258-21-1C21H16N2O
N-(2-Bromophenyl)-2-cyano-3-(naphthalen-1-yl)prop-2-enamide chemical structure, C20H13BrN2O, CAS 380564-76-1
N-(2-Bromophenyl)-2-cyano-3-(naphthalen-1-yl)prop-2-enamide
CAS 380564-76-1C20H13BrN2O
(E)-N-(2-Chlorophenyl)-2-cyano-3-naphthalen-1-ylprop-2-enamide chemical structure, C20H13ClN2O, CAS 341953-33-1
(E)-N-(2-Chlorophenyl)-2-cyano-3-naphthalen-1-ylprop-2-enamide
CAS 341953-33-1C20H13ClN2O
N-(4-Butylphenyl)-2-cyano-3-(naphthalen-1-yl)prop-2-enamide chemical structure, C24H22N2O, CAS 478848-86-1
N-(4-Butylphenyl)-2-cyano-3-(naphthalen-1-yl)prop-2-enamide
CAS 478848-86-1C24H22N2O