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Murcko scaffold

(1H-Indol-3-yl)(piperazin-1-yl)methanone scaffold

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
21
With full pages
0
Scaffold SMILES

O=C(c1c[nH]c2ccccc12)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the (1H-Indol-3-yl)(piperazin-1-yl)methanone page
Murcko scaffold O=C(c1c[nH]c2ccccc12)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

(5-Methoxy-1,2-dimethylindol-3-yl)-(4-methylpiperazin-1-yl)methanone chemical structure, C17H23N3O2, CAS 4819-54-9
(5-Methoxy-1,2-dimethylindol-3-yl)-(4-methylpiperazin-1-yl)methanone
CAS 4819-54-9C17H23N3O2
(1H-Indol-3-yl)(piperazin-1-yl)methanone chemical structure, C13H15N3O, CAS 610802-16-9
(1H-Indol-3-yl)(piperazin-1-yl)methanone
CAS 610802-16-9C13H15N3O
N-{[4-(1H-indol-3-ylcarbonyl)piperazin-1-yl]carbonyl}-beta-alanine chemical structure, C17H20N4O4, CAS 929823-13-2
N-{[4-(1H-indol-3-ylcarbonyl)piperazin-1-yl]carbonyl}-beta-alanine
CAS 929823-13-2C17H20N4O4
tert-Butyl 4-(1H-indole-3-carbonyl)piperazine-1-carboxylate chemical structure, C18H23N3O3, CAS 919738-75-3
tert-Butyl 4-(1H-indole-3-carbonyl)piperazine-1-carboxylate
CAS 919738-75-3C18H23N3O3
N-{[4-(1H-indol-3-ylcarbonyl)piperazin-1-yl]carbonyl}-L-methionine chemical structure, C19H24N4O4S, CAS 1013753-74-6
N-{[4-(1H-indol-3-ylcarbonyl)piperazin-1-yl]carbonyl}-L-methionine
CAS 1013753-74-6C19H24N4O4S
2,2-Dimethyl-1-{4-[(1-methyl-1H-indol-3-yl)carbonyl]piperazin-1-yl}propan-1-one chemical structure, C19H25N3O2, CAS 1081145-03-0
2,2-Dimethyl-1-{4-[(1-methyl-1H-indol-3-yl)carbonyl]piperazin-1-yl}propan-1-one
CAS 1081145-03-0C19H25N3O2
[4-(1H-Indol-3-ylcarbonyl)piperazin-1-yl](oxo)acetic acid chemical structure, C15H15N3O4, CAS 1081117-02-3
[4-(1H-Indol-3-ylcarbonyl)piperazin-1-yl](oxo)acetic acid
CAS 1081117-02-3C15H15N3O4
5-[4-(1H-Indol-3-ylcarbonyl)piperazin-1-yl]-5-oxopentanoic acid chemical structure, C18H21N3O4, CAS 1081114-64-8
5-[4-(1H-Indol-3-ylcarbonyl)piperazin-1-yl]-5-oxopentanoic acid
CAS 1081114-64-8C18H21N3O4
4-[4-(1H-Indol-3-ylcarbonyl)piperazin-1-yl]-N-(2-methylpropyl)-4-oxobutanamide chemical structure, C21H28N4O3, CAS 1081128-43-9
4-[4-(1H-Indol-3-ylcarbonyl)piperazin-1-yl]-N-(2-methylpropyl)-4-oxobutanamide
CAS 1081128-43-9C21H28N4O3
4-[4-(1H-Indole-3-carbonyl)piperazin-1-yl]-4-oxobutanoic acid chemical structure, C17H19N3O4, CAS 1081138-53-5
4-[4-(1H-Indole-3-carbonyl)piperazin-1-yl]-4-oxobutanoic acid
CAS 1081138-53-5C17H19N3O4
N,N-Dimethyl-4-[(1-methyl-1H-indol-3-yl)carbonyl]piperazine-1-sulfonamide chemical structure, C16H22N4O3S, CAS 1401599-40-3
N,N-Dimethyl-4-[(1-methyl-1H-indol-3-yl)carbonyl]piperazine-1-sulfonamide
CAS 1401599-40-3C16H22N4O3S
Ethyl {4-[(1-methyl-1H-indol-3-yl)carbonyl]piperazin-1-yl}(oxo)acetate chemical structure, C18H21N3O4, CAS 1144497-11-9
Ethyl {4-[(1-methyl-1H-indol-3-yl)carbonyl]piperazin-1-yl}(oxo)acetate
CAS 1144497-11-9C18H21N3O4
(1-Methyl-1H-indol-3-yl)(piperazin-1-yl)methanone chemical structure, C14H17N3O, CAS 1146293-65-3
(1-Methyl-1H-indol-3-yl)(piperazin-1-yl)methanone
CAS 1146293-65-3C14H17N3O
3-(Piperazine-1-carbonyl)-1H-indole hydrochloride chemical structure, C13H16ClN3O, CAS 1172808-41-1
3-(Piperazine-1-carbonyl)-1H-indole hydrochloride
CAS 1172808-41-1C13H16ClN3O
tert-Butyl 4-[(1-methyl-1H-indol-3-yl)carbonyl]piperazine-1-carboxylate chemical structure, C19H25N3O3, CAS 1325340-68-8
tert-Butyl 4-[(1-methyl-1H-indol-3-yl)carbonyl]piperazine-1-carboxylate
CAS 1325340-68-8C19H25N3O3
(1-Methylindol-3-yl)-piperazin-1-ylmethanone, hydrochloride chemical structure, C14H18ClN3O, CAS 1224160-34-2
(1-Methylindol-3-yl)-piperazin-1-ylmethanone, hydrochloride
CAS 1224160-34-2C14H18ClN3O
(6-Fluoro-1-methyl-1H-indol-3-yl)(piperazin-1-yl)methanone chemical structure, C14H16FN3O, CAS 1368687-33-5
(6-Fluoro-1-methyl-1H-indol-3-yl)(piperazin-1-yl)methanone
CAS 1368687-33-5C14H16FN3O
Mepirapim chemical structure, C19H27N3O, CAS 2365542-29-4
Mepirapim
CAS 2365542-29-4C19H27N3O
Mepirapim(hydrochloride) chemical structure, C19H28ClN3O, CAS 2365542-30-7
Mepirapim(hydrochloride)
CAS 2365542-30-7C19H28ClN3O
tert-Butyl 4-(5-bromo-1H-indole-3-carbonyl)piperazine-1-carboxylate chemical structure, C18H22BrN3O3, CAS 927570-42-1
tert-Butyl 4-(5-bromo-1H-indole-3-carbonyl)piperazine-1-carboxylate
CAS 927570-42-1C18H22BrN3O3
(5-Bromo-1-methyl-1H-indol-3-yl)(4-methylpiperazin-1-yl)methanone chemical structure, C15H18BrN3O, CAS 521276-52-8
(5-Bromo-1-methyl-1H-indol-3-yl)(4-methylpiperazin-1-yl)methanone
CAS 521276-52-8C15H18BrN3O