Murcko scaffold
Ring system with 2 rings and 16 atoms
51 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 51
- With full pages
- 18
Scaffold SMILES
O=C(NN=Cc1ccccc1)c1ccoc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 51 chemicals
![N'-[(E)-1-(3-Aminophenyl)ethylidene]-2-methyl-3-furohydrazide chemical structure, C14H15N3O2, CAS 356767-86-7](/s/CBWIIIPHKDCHHY-UHFFFAOYSA-N.svg)
N'-[(E)-1-(3-Aminophenyl)ethylidene]-2-methyl-3-furohydrazide
CAS 356767-86-7C14H15N3O2
![2,5-Dimethyl-3-furancarboxylic acid 2-[(4-nitrophenyl)methylene]hydrazide chemical structure, C14H13N3O4, CAS 159881-96-6](/s/KNKOMASVXMDLMF-UHFFFAOYSA-N.svg)
2,5-Dimethyl-3-furancarboxylic acid 2-[(4-nitrophenyl)methylene]hydrazide
CAS 159881-96-6C14H13N3O4
![2-Methyl-3-furancarboxylic acid 2-[(3-chloro-4-methoxyphenyl)methylene]hydrazide chemical structure, C14H13ClN2O3, CAS 861506-82-3](/s/UIIIQCVTBQABLU-UHFFFAOYSA-N.svg)
2-Methyl-3-furancarboxylic acid 2-[(3-chloro-4-methoxyphenyl)methylene]hydrazide
CAS 861506-82-3C14H13ClN2O3
![N-[(E)-(2-Chloro-6-fluorophenyl)methylideneamino]-2-methylfuran-3-carboxamide chemical structure, C13H10ClFN2O2, CAS 304906-18-1](/s/CSGVYRWNWXPMDU-FRKPEAEDSA-N.svg)
N-[(E)-(2-Chloro-6-fluorophenyl)methylideneamino]-2-methylfuran-3-carboxamide
CAS 304906-18-1C13H10ClFN2O2
![N-[(E)-(2,4-Dichlorophenyl)methylideneamino]-2-methylfuran-3-carboxamide chemical structure, C13H10Cl2N2O2, CAS 292612-12-5](/s/MZRNEZATYKTHKB-FRKPEAEDSA-N.svg)
N-[(E)-(2,4-Dichlorophenyl)methylideneamino]-2-methylfuran-3-carboxamide
CAS 292612-12-5C13H10Cl2N2O2
![2-Methyl-N-[(E)-(4-methylphenyl)methylideneamino]furan-3-carboxamide chemical structure, C14H14N2O2, CAS 304906-46-5](/s/KDCCYFXOTAWPLO-OQLLNIDSSA-N.svg)
2-Methyl-N-[(E)-(4-methylphenyl)methylideneamino]furan-3-carboxamide
CAS 304906-46-5C14H14N2O2
![N-[(E)-(2,6-Dichlorophenyl)methylideneamino]-2-methylfuran-3-carboxamide chemical structure, C13H10Cl2N2O2, CAS 292612-01-2](/s/FPULTYUJBNNMHE-FRKPEAEDSA-N.svg)
N-[(E)-(2,6-Dichlorophenyl)methylideneamino]-2-methylfuran-3-carboxamide
CAS 292612-01-2C13H10Cl2N2O2
![2-Methyl-N-[(E)-(4-propan-2-ylphenyl)methylideneamino]furan-3-carboxamide chemical structure, C16H18N2O2, CAS 292612-20-5](/s/FMGOKOSGOXZDPS-LICLKQGHSA-N.svg)
2-Methyl-N-[(E)-(4-propan-2-ylphenyl)methylideneamino]furan-3-carboxamide
CAS 292612-20-5C16H18N2O2
![2-Methyl-N'-[(E)-(3,4,5-trimethoxyphenyl)methylidene]furan-3-carbohydrazide chemical structure, C16H18N2O5, CAS 304906-23-8](/s/ZUBHKECLEOPFHN-RQZCQDPDSA-N.svg)
2-Methyl-N'-[(E)-(3,4,5-trimethoxyphenyl)methylidene]furan-3-carbohydrazide
CAS 304906-23-8C16H18N2O5
![N-[(E)-(2,3-Dichlorophenyl)methylideneamino]-2-methylfuran-3-carboxamide chemical structure, C13H10Cl2N2O2, CAS 292611-94-0](/s/KPGSJTXJKREZOD-FRKPEAEDSA-N.svg)
N-[(E)-(2,3-Dichlorophenyl)methylideneamino]-2-methylfuran-3-carboxamide
CAS 292611-94-0C13H10Cl2N2O2
![N-[(E)-(2-Chlorophenyl)methylideneamino]-2-methylfuran-3-carboxamide chemical structure, C13H11ClN2O2, CAS 304906-44-3](/s/UNKOORQYJWUHMI-OVCLIPMQSA-N.svg)
N-[(E)-(2-Chlorophenyl)methylideneamino]-2-methylfuran-3-carboxamide
CAS 304906-44-3C13H11ClN2O2
![N-[(E)-(3-Hydroxyphenyl)methylideneamino]-2-methylfuran-3-carboxamide chemical structure, C13H12N2O3, CAS 292611-96-2](/s/XEWMTNXFMNRZTR-RIYZIHGNSA-N.svg)
N-[(E)-(3-Hydroxyphenyl)methylideneamino]-2-methylfuran-3-carboxamide
CAS 292611-96-2C13H12N2O3
![2-Methyl-N'-[(E)-(2-methylphenyl)methylidene]furan-3-carbohydrazide chemical structure, C14H14N2O2, CAS 315206-02-1](/s/IVYXKFCDEYCVSD-OQLLNIDSSA-N.svg)
2-Methyl-N'-[(E)-(2-methylphenyl)methylidene]furan-3-carbohydrazide
CAS 315206-02-1C14H14N2O2
![N-[(E)-(2-Bromophenyl)methylideneamino]-2-methylfuran-3-carboxamide chemical structure, C13H11BrN2O2, CAS 292612-05-6](/s/XHFBFAJAEFTLSW-OVCLIPMQSA-N.svg)
N-[(E)-(2-Bromophenyl)methylideneamino]-2-methylfuran-3-carboxamide
CAS 292612-05-6C13H11BrN2O2
![N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-2-methylfuran-3-carboxamide chemical structure, C15H16N2O4, CAS 292612-18-1](/s/ATFFNXUXUOWKGD-CXUHLZMHSA-N.svg)
N-[(E)-(3,4-Dimethoxyphenyl)methylideneamino]-2-methylfuran-3-carboxamide
CAS 292612-18-1C15H16N2O4
![2-Methyl-N-[(E)-(4-methylsulfanylphenyl)methylideneamino]furan-3-carboxamide chemical structure, C14H14N2O2S, CAS 304906-25-0](/s/VHDAXWPDJLMZLL-OQLLNIDSSA-N.svg)
2-Methyl-N-[(E)-(4-methylsulfanylphenyl)methylideneamino]furan-3-carboxamide
CAS 304906-25-0C14H14N2O2S
(E)-Methyl 4-((2-(2,5-dimethylfuran-3-carbonyl)hydrazono)methyl)benzoate
CAS 304906-63-6C16H16N2O4
![N-[(E)-(4-Chlorophenyl)methylideneamino]-2-methylfuran-3-carboxamide chemical structure, C13H11ClN2O2, CAS 292612-22-7](/s/DILCVDMQTRZQLC-OVCLIPMQSA-N.svg)
N-[(E)-(4-Chlorophenyl)methylideneamino]-2-methylfuran-3-carboxamide
CAS 292612-22-7C13H11ClN2O2
![N-[(E)-Benzylideneamino]-2-methylfuran-3-carboxamide chemical structure, C13H12N2O2, CAS 304906-30-7](/s/KNUDMTRUPPNNOA-NTEUORMPSA-N.svg)
N-[(E)-Benzylideneamino]-2-methylfuran-3-carboxamide
CAS 304906-30-7C13H12N2O2
![N-[(E)-[4-(Diethylamino)phenyl]methylideneamino]-2-methylfuran-3-carboxamide chemical structure, C17H21N3O2, CAS 304906-47-6](/s/VIZYZRLCTHYIJW-LDADJPATSA-N.svg)
N-[(E)-[4-(Diethylamino)phenyl]methylideneamino]-2-methylfuran-3-carboxamide
CAS 304906-47-6C17H21N3O2
![N-[(E)-(4-Bromophenyl)methylideneamino]-2,5-dimethylfuran-3-carboxamide chemical structure, C14H13BrN2O2, CAS 304906-91-0](/s/XHDKSBVKAPLTSI-PXNMLYILSA-N.svg)
N-[(E)-(4-Bromophenyl)methylideneamino]-2,5-dimethylfuran-3-carboxamide
CAS 304906-91-0C14H13BrN2O2
![N'-[(E)-(2-Chlorophenyl)methylidene]-2,5-dimethylfuran-3-carbohydrazide chemical structure, C14H13ClN2O2, CAS 304906-99-8](/s/FJRZOBVXRWVIIQ-PXNMLYILSA-N.svg)
N'-[(E)-(2-Chlorophenyl)methylidene]-2,5-dimethylfuran-3-carbohydrazide
CAS 304906-99-8C14H13ClN2O2
![N'-[(E)-(3,4-Dimethoxyphenyl)methylidene]-2,5-dimethylfuran-3-carbohydrazide chemical structure, C16H18N2O4, CAS 304907-00-4](/s/ZUHSAROFRQDYNB-MFOYZWKCSA-N.svg)
N'-[(E)-(3,4-Dimethoxyphenyl)methylidene]-2,5-dimethylfuran-3-carbohydrazide
CAS 304907-00-4C16H18N2O4
2,5-Dimethyl-furan-3-carboxylic acid (4-methyl-benzylidene)-hydrazide
CAS 159881-97-7C15H16N2O2
- N'-[(E)-(4-Isopropylphenyl)methylidene]-2,5-dimethyl-3-furohydrazide304907-02-6C17H20N2O2
- N'-[(E)-(2-Methoxyphenyl)methylidene]-2,5-dimethylfuran-3-carbohydrazide304907-05-9C15H16N2O3
- N-[(Z)-1-(4-Chlorophenyl)ethylideneamino]-2,5-dimethylfuran-3-carboxamide304907-27-5C15H15ClN2O2
- 2-Methyl-N-[(E)-1-phenylethylideneamino]furan-3-carboxamide328914-05-2C14H14N2O2
- 2,5-Dimethyl-N-[(E)-(3,4,5-trimethoxyphenyl)methylideneamino]furan-3-carboxamide304906-67-0C17H20N2O5
- N'-[(1Z)-1-(4-Methoxyphenyl)ethylidene]-2,5-dimethylfuran-3-carbohydrazide304907-15-1C16H18N2O3
- N'-(1-(3,4-Dichlorophenyl)ethylidene)-2-methyl-3-furohydrazide315205-72-2C14H12Cl2N2O2
- N'-(1-(3-Bromophenyl)ethylidene)-2-methyl-3-furohydrazide315205-77-7C14H13BrN2O2
- N-[(E)-(2,5-Dimethoxyphenyl)methylideneamino]-2,5-dimethylfuran-3-carboxamide304906-60-3C16H18N2O4
- 2-Methyl-N-[(E)-(2-nitrophenyl)methylideneamino]furan-3-carboxamide304906-13-6C13H11N3O4
- N'-[(E)-(2-Chloro-5-nitrophenyl)methylidene]-2-methylfuran-3-carbohydrazide315206-03-2C13H10ClN3O4
- N-[(E)-(3-Methoxyphenyl)methylideneamino]-2-methylfuran-3-carboxamide315205-88-0C14H14N2O3
- 2,5-Dimethyl-N-[(E)-(2-nitrophenyl)methylideneamino]furan-3-carboxamide292612-29-4C14H13N3O4
- N-[(E)-Benzylideneamino]-2,5-dimethylfuran-3-carboxamide304906-82-9C14H14N2O2
- 2,5-Dimethyl-N-[(E)-(2,3,4-trimethoxyphenyl)methylideneamino]furan-3-carboxamide304906-73-8C17H20N2O5
- 2-Methyl-N'-((3-(trifluoromethyl)phenyl)methylene)-3-furohydrazide329699-42-5C14H11F3N2O2
- N'-[(E)-(3-Ethoxy-4-hydroxyphenyl)methylidene]-2,5-dimethylfuran-3-carbohydrazide304907-03-7C16H18N2O4
- N'-[(E)-(2-Hydroxy-3-methoxyphenyl)methylidene]-2,5-dimethylfuran-3-carbohydrazide292612-27-2C15H16N2O4
- (E)-N'-(3-Allyl-2-hydroxybenzylidene)-2,5-dimethylfuran-3-carbohydrazide304906-95-4C17H18N2O3
- N'-[(E)-(5-Bromo-2-hydroxyphenyl)methylidene]-2,5-dimethylfuran-3-carbohydrazide304906-66-9C14H13BrN2O3
- N'-[(E)-(2,4-Dihydroxyphenyl)methylidene]-2-methylfuran-3-carbohydrazide304906-35-2C13H12N2O4
- N'-[(E)-(2-Hydroxy-3,5-diiodophenyl)methylidene]-2-methylfuran-3-carbohydrazide315206-01-0C13H10I2N2O3
- N'-{(E)-[4-(diethylamino)-2-hydroxyphenyl]methylidene}-2-methylfuran-3-carbohydrazide304906-29-4C17H21N3O3
- N'-[(E)-(2-Hydroxy-3-methoxyphenyl)methylidene]-2-methylfuran-3-carbohydrazide304906-07-8C14H14N2O4
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=C(CSc1nnc[nH]1)Nc1ccccc1](/scaffold/VJBDIQRNSVRUDP-UHFFFAOYSA-N/structure.svg)
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