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Murcko scaffold

2-(1H-Pyrazol-1-yl)thiazole scaffold

153 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
153
With full pages
9
Scaffold SMILES

c1cnn(-c2nccs2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1H-Pyrazol-1-yl)thiazole page
Murcko scaffold c1cnn(-c2nccs2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 153 chemicals

Thiazole, 2-(4-aminopyrazol-1-yl)-4-methyl- chemical structure, C7H8N4S, CAS 28466-08-2
Thiazole, 2-(4-aminopyrazol-1-yl)-4-methyl-
CAS 28466-08-2C7H8N4S
Thiazole, 2-(4-(dimethylamino)pyrazol-1-yl)-4-methyl-, dihydrochloride chemical structure, C9H14Cl2N4S, CAS 28469-09-2
Thiazole, 2-(4-(dimethylamino)pyrazol-1-yl)-4-methyl-, dihydrochloride
CAS 28469-09-2C9H14Cl2N4S
Thiazole, 2-(3,5-dimethyl-1-pyrazolyl)-4-methyl- chemical structure, C9H11N3S, CAS 75007-32-8
Thiazole, 2-(3,5-dimethyl-1-pyrazolyl)-4-methyl-
CAS 75007-32-8C9H11N3S
2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid chemical structure, C9H6F3N3O2S, CAS 449778-74-9
2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid
CAS 449778-74-9C9H6F3N3O2S
Ethyl 5-(trifluoromethyl)-1-[4-(trifluoromethyl)-1,3-thiazol-2-yl]-1H-pyrazole-4-carboxylate chemical structure, C11H7F6N3O2S, CAS 956193-97-8
Ethyl 5-(trifluoromethyl)-1-[4-(trifluoromethyl)-1,3-thiazol-2-yl]-1H-pyrazole-4-carboxylate
CAS 956193-97-8C11H7F6N3O2S
4-(Chloromethyl)-2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole chemical structure, C9H7ClF3N3S, CAS 955976-93-9
4-(Chloromethyl)-2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole
CAS 955976-93-9C9H7ClF3N3S
4-Methyl-2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole-5-carboxylic acid chemical structure, C10H8F3N3O2S, CAS 955966-63-9
4-Methyl-2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole-5-carboxylic acid
CAS 955966-63-9C10H8F3N3O2S
Ethyl 2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylate chemical structure, C11H10F3N3O2S, CAS 955975-47-0
Ethyl 2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylate
CAS 955975-47-0C11H10F3N3O2S
N-Methyl-2-({2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)-1-hydrazinecarbothioamide chemical structure, C11H11F3N6OS2, CAS 955976-39-3
N-Methyl-2-({2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)-1-hydrazinecarbothioamide
CAS 955976-39-3C11H11F3N6OS2
2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-(trifluoromethyl)-1,3-thiazole chemical structure, C9H5F6N3S, CAS 956964-72-0
2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-4-(trifluoromethyl)-1,3-thiazole
CAS 956964-72-0C9H5F6N3S
N'-({2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)methanesulfonohydrazide chemical structure, C10H10F3N5O3S2, CAS 955966-50-4
N'-({2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)methanesulfonohydrazide
CAS 955966-50-4C10H10F3N5O3S2
Ethyl 1-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate chemical structure, C13H12F3N3O3S, CAS 955964-60-0
Ethyl 1-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate
CAS 955964-60-0C13H12F3N3O3S
1-{5-Methyl-2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}-1-ethanone chemical structure, C11H10F3N3OS, CAS 956754-81-7
1-{5-Methyl-2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}-1-ethanone
CAS 956754-81-7C11H10F3N3OS
2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole-4-carbohydrazide chemical structure, C9H8F3N5OS, CAS 955964-92-8
2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole-4-carbohydrazide
CAS 955964-92-8C9H8F3N5OS
2-(3,5-Dimethyl-pyrazol-1-yl)-thiazole-4-carboxylic acid chemical structure, C9H9N3O2S, CAS 957293-86-6
2-(3,5-Dimethyl-pyrazol-1-yl)-thiazole-4-carboxylic acid
CAS 957293-86-6C9H9N3O2S
{2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}methanol chemical structure, C9H8F3N3OS, CAS 959582-07-1
{2-[3-Methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}methanol
CAS 959582-07-1C9H8F3N3OS
Ethyl 2-(5-amino-4-cyano-1H-pyrazol-1-yl)-4-methyl-1,3-thiazole-5-carboxylate chemical structure, C11H11N5O2S, CAS 956369-38-3
Ethyl 2-(5-amino-4-cyano-1H-pyrazol-1-yl)-4-methyl-1,3-thiazole-5-carboxylate
CAS 956369-38-3C11H11N5O2S
Ethyl 2-[5-amino-4-(ethoxycarbonyl)-1H-pyrazol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate chemical structure, C13H16N4O4S, CAS 956369-39-4
Ethyl 2-[5-amino-4-(ethoxycarbonyl)-1H-pyrazol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate
CAS 956369-39-4C13H16N4O4S
5-(Trifluoromethyl)-1-[4-(trifluoromethyl)-1,3-thiazol-2-yl]-1H-pyrazole-4-carboxylic acid chemical structure, C9H3F6N3O2S, CAS 956778-75-9
5-(Trifluoromethyl)-1-[4-(trifluoromethyl)-1,3-thiazol-2-yl]-1H-pyrazole-4-carboxylic acid
CAS 956778-75-9C9H3F6N3O2S
Ethyl 4-methyl-2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole-5-carboxylate chemical structure, C12H12F3N3O2S, CAS 956393-95-6
Ethyl 4-methyl-2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole-5-carboxylate
CAS 956393-95-6C12H12F3N3O2S
N-Ethyl-2-({2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)-1-hydrazinecarbothioamide chemical structure, C12H13F3N6OS2, CAS 956625-81-3
N-Ethyl-2-({2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)-1-hydrazinecarbothioamide
CAS 956625-81-3C12H13F3N6OS2
N-Allyl-2-({2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)-1-hydrazinecarbothioamide chemical structure, C13H13F3N6OS2, CAS 956374-51-9
N-Allyl-2-({2-[3-methyl-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazol-4-yl}carbonyl)-1-hydrazinecarbothioamide
CAS 956374-51-9C13H13F3N6OS2
Ethyl 2-(3,5-dimethylpyrazol-1-yl)-4-methyl-1,3-thiazole-5-carboxylate chemical structure, C12H15N3O2S, CAS 91643-68-4
Ethyl 2-(3,5-dimethylpyrazol-1-yl)-4-methyl-1,3-thiazole-5-carboxylate
CAS 91643-68-4C12H15N3O2S
Ethyl 5-amino-1-(1,3-thiazol-2-yl)-1H-pyrazole-4-carboxylate chemical structure, C9H10N4O2S, CAS 112267-06-8
Ethyl 5-amino-1-(1,3-thiazol-2-yl)-1H-pyrazole-4-carboxylate
CAS 112267-06-8C9H10N4O2S