CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 17 atoms

24 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
24
With full pages
3
Scaffold SMILES

c1ccc(COC2COc3nccn3C2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(COC2COc3nccn3C2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

Pretomanid chemical structure, C14H12F3N3O5, CAS 187235-37-6
Pretomanid
CAS 187235-37-6C14H12F3N3O5
(3S)-3-((4-Butylphenyl)methoxy)-6-nitro-2H,3H,4H-imidazolo(2,1-b)1,3-oxazaperhydroine chemical structure, C17H21N3O4, CAS 187235-36-5
(3S)-3-((4-Butylphenyl)methoxy)-6-nitro-2H,3H,4H-imidazolo(2,1-b)1,3-oxazaperhydroine
CAS 187235-36-5C17H21N3O4
(3S)-3-((4-(tert-Butyl)phenyl)methoxy)-6-nitro-2H,3H,4H-imidazolo(2,1-b)1,3-oxazaperhydroine chemical structure, C17H21N3O4, CAS 187235-31-0
(3S)-3-((4-(tert-Butyl)phenyl)methoxy)-6-nitro-2H,3H,4H-imidazolo(2,1-b)1,3-oxazaperhydroine
CAS 187235-31-0C17H21N3O4
(S)-2-Nitro-6-(4-trifluoromethyl-benzyloxy)-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine chemical structure, C14H12F3N3O4, CAS 187235-26-3
(S)-2-Nitro-6-(4-trifluoromethyl-benzyloxy)-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine
CAS 187235-26-3C14H12F3N3O4
(S)-6-Benzyloxy-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine chemical structure, C13H13N3O4, CAS 187235-29-6
(S)-6-Benzyloxy-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine
CAS 187235-29-6C13H13N3O4
(S)-2-Nitro-6-pentafluorophenylmethoxy-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine chemical structure, C13H8F5N3O4, CAS 187235-30-9
(S)-2-Nitro-6-pentafluorophenylmethoxy-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine
CAS 187235-30-9C13H8F5N3O4
(S)-6-(2,4-Difluoro-benzyloxy)-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine chemical structure, C13H11F2N3O4, CAS 187235-32-1
(S)-6-(2,4-Difluoro-benzyloxy)-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine
CAS 187235-32-1C13H11F2N3O4
(S)-6-(4-Fluorobenzyloxy)-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine chemical structure, C13H12FN3O4, CAS 187235-33-2
(S)-6-(4-Fluorobenzyloxy)-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine
CAS 187235-33-2C13H12FN3O4
(S)-6-(4-Methoxy-benzyloxy)-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine chemical structure, C14H15N3O5, CAS 187235-34-3
(S)-6-(4-Methoxy-benzyloxy)-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine
CAS 187235-34-3C14H15N3O5
(R)-6-(4-tert-Butylbenzyloxy)-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine chemical structure, C17H21N3O4, CAS 187235-61-6
(R)-6-(4-tert-Butylbenzyloxy)-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine
CAS 187235-61-6C17H21N3O4
(R)-2-Nitro-6-(4-trifluoromethylbenzyloxy)-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine' chemical structure, C14H12F3N3O4, CAS 187235-56-9
(R)-2-Nitro-6-(4-trifluoromethylbenzyloxy)-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine'
CAS 187235-56-9C14H12F3N3O4
(S)-2-Nitro-6-(4-octyl-benzyloxy)-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine chemical structure, C21H29N3O4, CAS 187235-41-2
(S)-2-Nitro-6-(4-octyl-benzyloxy)-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine
CAS 187235-41-2C21H29N3O4
(R)-6-(4-Fluoro-benzyloxy)-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine chemical structure, C13H12FN3O4, CAS 187235-63-8
(R)-6-(4-Fluoro-benzyloxy)-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine
CAS 187235-63-8C13H12FN3O4
(R)-6-Benzyloxy-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine chemical structure, C13H13N3O4, CAS 187235-59-2
(R)-6-Benzyloxy-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine
CAS 187235-59-2C13H13N3O4
(R)-2-Nitro-6-pentafluorophenylmethoxy-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine chemical structure, C13H8F5N3O4, CAS 187235-60-5
(R)-2-Nitro-6-pentafluorophenylmethoxy-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine
CAS 187235-60-5C13H8F5N3O4
(R)-6-(2,4-Difluoro-benzyloxy)-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine chemical structure, C13H11F2N3O4, CAS 187235-62-7
(R)-6-(2,4-Difluoro-benzyloxy)-2-nitro-6,7-dihydro-5H-imidazo(2,1-b)(1,3)oxazine
CAS 187235-62-7C13H11F2N3O4
(6R)-2-Nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine chemical structure, C14H12F3N3O5, CAS 1105708-11-9
(6R)-2-Nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine
CAS 1105708-11-9C14H12F3N3O5
2-Nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine chemical structure, C14H12F3N3O5, CAS 943720-74-9
2-Nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine
CAS 943720-74-9C14H12F3N3O5
Desnitro pretomanid chemical structure, C14H13F3N2O3, CAS 1131005-00-9
Desnitro pretomanid
CAS 1131005-00-9C14H13F3N2O3
(6S)-3-Nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine chemical structure, C14H12F3N3O5, CAS 1131004-99-3
(6S)-3-Nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine
CAS 1131004-99-3C14H12F3N3O5
(S)-2-Nitro-6-((3-(trifluoromethoxy)benzyl)oxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine chemical structure, C14H12F3N3O5, CAS 1353753-57-7
(S)-2-Nitro-6-((3-(trifluoromethoxy)benzyl)oxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine
CAS 1353753-57-7C14H12F3N3O5
(6S)-2-Nitro-6-[[2-(trifluoromethoxy)phenyl]methoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine chemical structure, C14H12F3N3O5, CAS 1353753-55-5
(6S)-2-Nitro-6-[[2-(trifluoromethoxy)phenyl]methoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine
CAS 1353753-55-5C14H12F3N3O5
Pretomanid-d4 chemical structure, C14H12F3N3O5, CAS 1346617-34-2
Pretomanid-d4
CAS 1346617-34-2C14H12F3N3O5
Pretomanid impurity 12 chemical structure, C15H14F3N3O5, CAS 2151045-16-6
Pretomanid impurity 12
CAS 2151045-16-6C15H14F3N3O5