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Murcko scaffold

Ring system with 3 rings and 20 atoms

114 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
114
With full pages
3
Scaffold SMILES

O=C(CSc1ccccc1)Nc1nc2ccccc2s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1ccccc1)Nc1nc2ccccc2s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 114 chemicals

N-(6-Methoxy-1,3-benzothiazol-2-yl)-2-(phenylsulfanyl)acetamide chemical structure, C16H14N2O2S2, CAS 353253-41-5
N-(6-Methoxy-1,3-benzothiazol-2-yl)-2-(phenylsulfanyl)acetamide
CAS 353253-41-5C16H14N2O2S2
N-(6-Ethoxybenzo[d]thiazol-2-yl)-2-(phenylthio)acetamide chemical structure, C17H16N2O2S2, CAS 775316-97-7
N-(6-Ethoxybenzo[d]thiazol-2-yl)-2-(phenylthio)acetamide
CAS 775316-97-7C17H16N2O2S2
N-(6-Methyl-1,3-benzothiazol-2-yl)-2-(4-methylphenyl)sulfanylacetamide chemical structure, C17H16N2OS2, CAS 701224-25-1
N-(6-Methyl-1,3-benzothiazol-2-yl)-2-(4-methylphenyl)sulfanylacetamide
CAS 701224-25-1C17H16N2OS2
N-(6-Methyl-1,3-benzothiazol-2-yl)-2-(phenylsulfanyl)acetamide chemical structure, C16H14N2OS2, CAS 724735-16-4
N-(6-Methyl-1,3-benzothiazol-2-yl)-2-(phenylsulfanyl)acetamide
CAS 724735-16-4C16H14N2OS2
2-[(4-Chlorophenyl)sulfanyl]-N-(6-fluoro-1,3-benzothiazol-2-yl)acetamide chemical structure, C15H10ClFN2OS2, CAS 673488-85-2
2-[(4-Chlorophenyl)sulfanyl]-N-(6-fluoro-1,3-benzothiazol-2-yl)acetamide
CAS 673488-85-2C15H10ClFN2OS2
N-(4-Chloro-1,3-benzothiazol-2-yl)-2-(4-chlorophenyl)sulfanylacetamide chemical structure, C15H10Cl2N2OS2, CAS 709005-92-5
N-(4-Chloro-1,3-benzothiazol-2-yl)-2-(4-chlorophenyl)sulfanylacetamide
CAS 709005-92-5C15H10Cl2N2OS2
N-(6-Chloro-1,3-benzothiazol-2-yl)-2-(4-chlorophenyl)sulfanylacetamide chemical structure, C15H10Cl2N2OS2, CAS 637315-14-1
N-(6-Chloro-1,3-benzothiazol-2-yl)-2-(4-chlorophenyl)sulfanylacetamide
CAS 637315-14-1C15H10Cl2N2OS2
N-(Benzo[d]thiazol-2-yl)-2-((4-fluorophenyl)thio)acetamide chemical structure, C15H11FN2OS2, CAS 839696-71-8
N-(Benzo[d]thiazol-2-yl)-2-((4-fluorophenyl)thio)acetamide
CAS 839696-71-8C15H11FN2OS2
2-[(4-Chlorophenyl)sulfanyl]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide chemical structure, C17H15ClN2O2S2, CAS 445416-00-2
2-[(4-Chlorophenyl)sulfanyl]-N-(6-ethoxy-1,3-benzothiazol-2-yl)acetamide
CAS 445416-00-2C17H15ClN2O2S2
N-(Benzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide chemical structure, C16H14N2OS2, CAS 403836-11-3
N-(Benzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide
CAS 403836-11-3C16H14N2OS2
2-Phenylsulfanyl-N-(3,5,7-trimethyl-1,3-benzothiazol-2-ylidene)acetamide chemical structure, C18H18N2OS2, CAS 898439-04-8
2-Phenylsulfanyl-N-(3,5,7-trimethyl-1,3-benzothiazol-2-ylidene)acetamide
CAS 898439-04-8C18H18N2OS2
N-(6-Methoxy-1,3-benzothiazol-2-yl)-2-[(4-methylphenyl)sulfanyl]acetamide chemical structure, C17H16N2O2S2, CAS 827010-69-5
N-(6-Methoxy-1,3-benzothiazol-2-yl)-2-[(4-methylphenyl)sulfanyl]acetamide
CAS 827010-69-5C17H16N2O2S2
N-(4-Methoxybenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide chemical structure, C17H16N2O2S2, CAS 895453-66-4
N-(4-Methoxybenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide
CAS 895453-66-4C17H16N2O2S2
N-(6-Nitrobenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide chemical structure, C16H13N3O3S2, CAS 885910-25-8
N-(6-Nitrobenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide
CAS 885910-25-8C16H13N3O3S2
N-(4-Chlorobenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide chemical structure, C16H13ClN2OS2, CAS 895453-99-3
N-(4-Chlorobenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide
CAS 895453-99-3C16H13ClN2OS2
N-(4-Methoxy-6-nitrobenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide chemical structure, C17H15N3O4S2, CAS 895454-13-4
N-(4-Methoxy-6-nitrobenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide
CAS 895454-13-4C17H15N3O4S2
N-(6-Acetamidobenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide chemical structure, C18H17N3O2S2, CAS 895454-38-3
N-(6-Acetamidobenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide
CAS 895454-38-3C18H17N3O2S2
N-(6-Fluorobenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide chemical structure, C16H13FN2OS2, CAS 895454-65-6
N-(6-Fluorobenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide
CAS 895454-65-6C16H13FN2OS2
N-(4-Fluorobenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide chemical structure, C16H13FN2OS2, CAS 895459-65-1
N-(4-Fluorobenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide
CAS 895459-65-1C16H13FN2OS2
N-(4,7-Dimethylbenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide chemical structure, C18H18N2OS2, CAS 895459-97-9
N-(4,7-Dimethylbenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide
CAS 895459-97-9C18H18N2OS2
N-(5,7-Dimethylbenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide chemical structure, C18H18N2OS2, CAS 895460-13-6
N-(5,7-Dimethylbenzo[d]thiazol-2-yl)-2-(p-tolylthio)acetamide
CAS 895460-13-6C18H18N2OS2
2-((4-Chlorophenyl)thio)-N-(6-nitrobenzo[d]thiazol-2-yl)acetamide chemical structure, C15H10ClN3O3S2, CAS 792946-46-4
2-((4-Chlorophenyl)thio)-N-(6-nitrobenzo[d]thiazol-2-yl)acetamide
CAS 792946-46-4C15H10ClN3O3S2
2-((4-Chlorophenyl)thio)-N-(4-methoxy-6-nitrobenzo[d]thiazol-2-yl)acetamide chemical structure, C16H12ClN3O4S2, CAS 898416-07-4
2-((4-Chlorophenyl)thio)-N-(4-methoxy-6-nitrobenzo[d]thiazol-2-yl)acetamide
CAS 898416-07-4C16H12ClN3O4S2
2-((4-Chlorophenyl)thio)-N-(6-(methylsulfonyl)benzo[d]thiazol-2-yl)acetamide chemical structure, C16H13ClN2O3S3, CAS 895470-51-6
2-((4-Chlorophenyl)thio)-N-(6-(methylsulfonyl)benzo[d]thiazol-2-yl)acetamide
CAS 895470-51-6C16H13ClN2O3S3