CompoundList
Murcko scaffold

2-Hydroxy-3-phenylpyridine scaffold

357 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
357
With full pages
3
Scaffold SMILES

O=c1[nH]cccc1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Murcko scaffold O=c1[nH]cccc1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 357 chemicals

2-Hydroxy-3-phenylpyridine chemical structure, C11H9NO, CAS 24228-13-5
2-Hydroxy-3-phenylpyridine
CAS 24228-13-5C11H9NO
1-Methyl-3-phenylpyridin-2-one chemical structure, C12H11NO, CAS 13180-21-7
1-Methyl-3-phenylpyridin-2-one
CAS 13180-21-7C12H11NO
2-Hydroxy-3-(4-methoxyphenyl)pyridine chemical structure, C12H11NO2, CAS 143074-71-9
2-Hydroxy-3-(4-methoxyphenyl)pyridine
CAS 143074-71-9C12H11NO2
3-(3-Chlorophenyl)-2-hydroxypyridine chemical structure, C11H8ClNO, CAS 143074-74-2
3-(3-Chlorophenyl)-2-hydroxypyridine
CAS 143074-74-2C11H8ClNO
2-Hydroxy-3-(3-nitrophenyl)pyridine chemical structure, C11H8N2O3, CAS 143074-73-1
2-Hydroxy-3-(3-nitrophenyl)pyridine
CAS 143074-73-1C11H8N2O3
3-Fluorophenylpyridone chemical structure, C11H8FNO, CAS 143074-72-0
3-Fluorophenylpyridone
CAS 143074-72-0C11H8FNO
2-Hydroxy-3-(2-methoxyphenyl)pyridine chemical structure, C12H11NO2, CAS 143074-70-8
2-Hydroxy-3-(2-methoxyphenyl)pyridine
CAS 143074-70-8C12H11NO2
5-Chloro-3-phenylpyridin-2(1H)-one chemical structure, C11H8ClNO, CAS 24228-17-9
5-Chloro-3-phenylpyridin-2(1H)-one
CAS 24228-17-9C11H8ClNO
6-Methylsulfanyl-3-phenyl-1H-pyridin-2-one chemical structure, C12H11NOS, CAS 828276-44-4
6-Methylsulfanyl-3-phenyl-1H-pyridin-2-one
CAS 828276-44-4C12H11NOS
2-Hydroxy-3-(3-methylphenyl)pyridine chemical structure, C12H11NO, CAS 143074-75-3
2-Hydroxy-3-(3-methylphenyl)pyridine
CAS 143074-75-3C12H11NO
6-Chloro-1-methyl-3-phenylpyridin-2(1H)-one chemical structure, C12H10ClNO, CAS 67970-91-6
6-Chloro-1-methyl-3-phenylpyridin-2(1H)-one
CAS 67970-91-6C12H10ClNO
2-Hydroxy-3-(3-methoxyphenyl)pyridine chemical structure, C12H11NO2, CAS 30081-70-0
2-Hydroxy-3-(3-methoxyphenyl)pyridine
CAS 30081-70-0C12H11NO2
3-(2-Hydroxyphenyl)pyridin-2(1H)-one chemical structure, C11H9NO2, CAS 1261971-11-2
3-(2-Hydroxyphenyl)pyridin-2(1H)-one
CAS 1261971-11-2C11H9NO2
3-(4-Chlorophenyl)-1-methyl-6-(trifluoromethyl)pyridin-2(1H)-one chemical structure, C13H9ClF3NO, CAS 194235-95-5
3-(4-Chlorophenyl)-1-methyl-6-(trifluoromethyl)pyridin-2(1H)-one
CAS 194235-95-5C13H9ClF3NO
3-(2,4-Dichlorophenyl)-6-trifluoromethyl-2(1H)-pyridone chemical structure, C12H6Cl2F3NO, CAS 194236-82-3
3-(2,4-Dichlorophenyl)-6-trifluoromethyl-2(1H)-pyridone
CAS 194236-82-3C12H6Cl2F3NO
2-Hydroxy-3-(4-methylsulfonylphenyl)pyridine chemical structure, C12H11NO3S, CAS 1224598-12-2
2-Hydroxy-3-(4-methylsulfonylphenyl)pyridine
CAS 1224598-12-2C12H11NO3S
5-Methyl-3-phenyl-2(1H)-pyridinone chemical structure, C12H11NO, CAS 53428-05-0
5-Methyl-3-phenyl-2(1H)-pyridinone
CAS 53428-05-0C12H11NO
3-(4-Chlorophenyl)pyridin-2(1H)-one chemical structure, C11H8ClNO, CAS 53428-04-9
3-(4-Chlorophenyl)pyridin-2(1H)-one
CAS 53428-04-9C11H8ClNO
2-Hydroxy-3-(3-trifluoromethylphenyl)pyridine chemical structure, C12H8F3NO, CAS 108281-81-8
2-Hydroxy-3-(3-trifluoromethylphenyl)pyridine
CAS 108281-81-8C12H8F3NO
2(1H)-Pyridinone, 4-amino-3-phenyl- chemical structure, C11H10N2O, CAS 1379307-36-4
2(1H)-Pyridinone, 4-amino-3-phenyl-
CAS 1379307-36-4C11H10N2O
6-Bromo-3-(4-bromophenyl)-1,2-dihydropyridin-2-one chemical structure, C11H7Br2NO, CAS 680214-14-6
6-Bromo-3-(4-bromophenyl)-1,2-dihydropyridin-2-one
CAS 680214-14-6C11H7Br2NO
3-(5-(tert-Butyl)-3-chloro-2-hydroxyphenyl)pyridin-2(1H)-one chemical structure, C15H16ClNO2, CAS 1206771-07-4
3-(5-(tert-Butyl)-3-chloro-2-hydroxyphenyl)pyridin-2(1H)-one
CAS 1206771-07-4C15H16ClNO2
3-(3-(tert-Butyl)-5-hydroxy-4-methoxyphenyl)pyridin-2(1H)-one chemical structure, C16H19NO3, CAS 1206771-17-6
3-(3-(tert-Butyl)-5-hydroxy-4-methoxyphenyl)pyridin-2(1H)-one
CAS 1206771-17-6C16H19NO3
3-(3-(tert-Butyl)-4,5-dimethoxyphenyl)pyridin-2(1H)-one chemical structure, C17H21NO3, CAS 1206771-20-1
3-(3-(tert-Butyl)-4,5-dimethoxyphenyl)pyridin-2(1H)-one
CAS 1206771-20-1C17H21NO3