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Murcko scaffold

(4-Benzylpiperazin-1-yl)(1H-indol-5-yl)methanone scaffold

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
8
With full pages
2
Scaffold SMILES

O=C(c1ccc2[nH]ccc2c1)N1CCN(Cc2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the (4-Benzylpiperazin-1-yl)(1H-indol-5-yl)methanone page
Murcko scaffold O=C(c1ccc2[nH]ccc2c1)N1CCN(Cc2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

Talmapimod chemical structure, C27H30ClFN4O3, CAS 309913-83-5
Talmapimod
CAS 309913-83-5C27H30ClFN4O3
N,N-Desmethyl talmapimod chemical structure, C26H28ClFN4O3, CAS 672293-10-6
N,N-Desmethyl talmapimod
CAS 672293-10-6C26H28ClFN4O3
Talmapimod hydrochloride chemical structure, C27H31Cl2FN4O3, CAS 309915-12-6
Talmapimod hydrochloride
CAS 309915-12-6C27H31Cl2FN4O3
(4-Benzylpiperazin-1-yl)(1H-indol-5-yl)methanone chemical structure, C20H21N3O, CAS 353522-46-0
(4-Benzylpiperazin-1-yl)(1H-indol-5-yl)methanone
CAS 353522-46-0C20H21N3O
6-Chloro-5-[[4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-alpha-oxo-1H-indole-3-acetamide chemical structure, C27H30ClFN4O3, CAS 309913-59-5
6-Chloro-5-[[4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-alpha-oxo-1H-indole-3-acetamide
CAS 309913-59-5C27H30ClFN4O3
(4-Benzylpiperazin-1-yl)(1-methyl-1H-indol-5-yl)methanone chemical structure, C21H23N3O, CAS 1219557-45-5
(4-Benzylpiperazin-1-yl)(1-methyl-1H-indol-5-yl)methanone
CAS 1219557-45-5C21H23N3O
Des-(N,N-dimethyl-2-oxoacetamide) Talmapimod chemical structure, C23H25ClFN3O, CAS 309915-19-3
Des-(N,N-dimethyl-2-oxoacetamide) Talmapimod
CAS 309915-19-3C23H25ClFN3O
Piperazine,1-[(4-chlorophenyl)methyl]-4-(1H-indol-5-ylcarbonyl)- chemical structure, C20H20ClN3O, CAS 251107-28-5
Piperazine,1-[(4-chlorophenyl)methyl]-4-(1H-indol-5-ylcarbonyl)-
CAS 251107-28-5C20H20ClN3O