Murcko scaffold
Ring system with 2 rings and 15 atoms
46 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 15
- Chemicals
- 46
- With full pages
- 3
Scaffold SMILES
O=C(NCc1ccccc1)c1ccoc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 46 of 46 chemicals
N-Benzyl-2-methylfuran-3-carboxamide
CAS 75596-44-0C13H13NO2
2,5-Dimethyl-N-(1-phenylpropyl)furan-3-carboxamide
CAS 492433-87-1C16H19NO2
2-Methyl-N-(1-phenylpropyl)furan-3-carboxamide
CAS 445004-03-5C15H17NO2
![N-[1-(3,4-Dimethoxyphenyl)ethyl]-2,5-dimethylfuran-3-carboxamide chemical structure, C17H21NO4, CAS 894649-59-3](/s/YKKBQMDJWMMCNG-UHFFFAOYSA-N.svg)
N-[1-(3,4-Dimethoxyphenyl)ethyl]-2,5-dimethylfuran-3-carboxamide
CAS 894649-59-3C17H21NO4
![N-[1-(4-Ethylphenyl)ethyl]-2-methylfuran-3-carboxamide chemical structure, C16H19NO2, CAS 894623-16-6](/s/LURJGTXXDJDBRP-UHFFFAOYSA-N.svg)
N-[1-(4-Ethylphenyl)ethyl]-2-methylfuran-3-carboxamide
CAS 894623-16-6C16H19NO2
![N-[1-(3-Methoxyphenyl)ethyl]-2,5-dimethylfuran-3-carboxamide chemical structure, C16H19NO3, CAS 894657-79-5](/s/MKPRBEGKWIFBDQ-UHFFFAOYSA-N.svg)
N-[1-(3-Methoxyphenyl)ethyl]-2,5-dimethylfuran-3-carboxamide
CAS 894657-79-5C16H19NO3
![2-Methyl-N-[1-(4-methylphenyl)propyl]furan-3-carboxamide chemical structure, C16H19NO2, CAS 894637-80-0](/s/QWWOFTXEPBKODP-UHFFFAOYSA-N.svg)
2-Methyl-N-[1-(4-methylphenyl)propyl]furan-3-carboxamide
CAS 894637-80-0C16H19NO2
![3-[(2-Methylfuran-3-carbonyl)amino]-3-phenylpropanoic acid chemical structure, C15H15NO4, CAS 926198-22-3](/s/SRTPZZYLHOBCMM-UHFFFAOYSA-N.svg)
3-[(2-Methylfuran-3-carbonyl)amino]-3-phenylpropanoic acid
CAS 926198-22-3C15H15NO4
2-(Furan-3-carboxamido)-2-phenylacetic acid
CAS 1103527-37-2C13H11NO4
N-(4-Bromobenzyl)furan-3-carboxamide
CAS 950225-91-9C12H10BrNO2
N-(2-Chlorobenzyl)furan-3-carboxamide
CAS 950231-69-3C12H10ClNO2
N-(1-(4-Bromophenyl)ethyl)furan-3-carboxamide
CAS 930419-64-0C13H12BrNO2
N-(1-(4-Fluorophenyl)ethyl)furan-3-carboxamide
CAS 1043249-46-2C13H12FNO2
N-(1-(2,4-Dichlorophenyl)ethyl)furan-3-carboxamide
CAS 1043307-20-5C13H11Cl2NO2
![4-[[[(2,5-Dimethyl-3-furanyl)carbonyl]amino]methyl]benzoic acid chemical structure, C15H15NO4, CAS 1016742-16-7](/s/BGTYFULAXZEQGM-UHFFFAOYSA-N.svg)
4-[[[(2,5-Dimethyl-3-furanyl)carbonyl]amino]methyl]benzoic acid
CAS 1016742-16-7C15H15NO4
N-(3-Chlorobenzyl)furan-3-carboxamide
CAS 1009209-10-2C12H10ClNO2
N-(4-Chlorobenzyl)furan-3-carboxamide
CAS 1326561-83-4C12H10ClNO2
N-(3-Sulfamoylbenzyl)furan-3-carboxamide
CAS 1100302-71-3C12H12N2O4S
5-Bromo-N-(2-methylbenzyl)furan-3-carboxamide
CAS 1994182-02-3C13H12BrNO2
N,2-dimethyl-N-((2-methylphenyl)methyl)furan-3-carboxamide
CAS 1089636-91-8C15H17NO2
N-(4-Bromobenzyl)-N-methylfuran-3-carboxamide
CAS 1090611-23-6C13H12BrNO2
N-(1-(3-Bromophenyl)ethyl)-2-methylfuran-3-carboxamide
CAS 1090405-10-9C14H14BrNO2
N-(1-(3-Bromophenyl)ethyl)furan-3-carboxamide
CAS 1090606-61-3C13H12BrNO2
![N-[(5-Amino-2-chlorophenyl)methyl]-N,2,5-trimethyl-3-furancarboxamide chemical structure, C15H17ClN2O2, CAS 1155956-37-8](/s/KDHSMLDACZAAFY-UHFFFAOYSA-N.svg)
N-[(5-Amino-2-chlorophenyl)methyl]-N,2,5-trimethyl-3-furancarboxamide
CAS 1155956-37-8C15H17ClN2O2
- N-[1-(4-Chlorophenyl)ethyl]-2,5-dimethylfuran-3-carboxamide1049120-98-0C15H16ClNO2
- N-(2-Chlorobenzyl)-2,5-dimethyl-4-(N-methylsulfamoyl)furan-3-carboxamide1207011-32-2C15H17ClN2O4S
- N-Benzyl-5-bromo-N-methylfuran-3-carboxamide1211725-28-8C13H12BrNO2
- N-(3-Cyanobenzyl)furan-3-carboxamide1209676-35-6C13H10N2O2
- N-(1-(2,4-Dichlorophenyl)ethyl)-2-methylfuran-3-carboxamide1623705-96-3C14H13Cl2NO2
- N-Benzyl-N-(cyanomethyl)-2,5-dimethylfuran-3-carboxamide1252520-92-5C16H16N2O2
- N-(1-(3-Chlorophenyl)ethyl)furan-3-carboxamide1330990-18-5C13H12ClNO2
- N-(3-Bromobenzyl)-2-methylfuran-3-carboxamide1306052-77-6C13H12BrNO2
- N-(3-Chloro-4-fluorobenzyl)furan-3-carboxamide2325347-69-9C12H9ClFNO2
- N-[Cyano(2-methylphenyl)methyl]furan-3-carboxamide1355508-13-2C14H12N2O2
- N-[Cyano(3,4-dichlorophenyl)methyl]furan-3-carboxamide1375186-68-7C13H8Cl2N2O2
- N-[Cyano(2,4-dimethoxyphenyl)methyl]furan-3-carboxamide1444370-09-5C15H14N2O4
- 2-Bromo-N-(2-methylbenzyl)furan-3-carboxamide1978985-87-3C13H12BrNO2
- 2-Bromo-N-(3-methylbenzyl)furan-3-carboxamide1968358-38-4C13H12BrNO2
- 2-Bromo-N-[cyano(2-methoxyphenyl)methyl]furan-3-carboxamide1808608-66-3C14H11BrN2O3
- N-[(2,4-Difluorophenyl)methyl]-2,5-dimethylfuran-3-carboxamide2326272-55-1C14H13F2NO2
- N-[(2,6-Difluorophenyl)methyl]furan-3-carboxamide2322190-43-0C12H9F2NO2
- N-(3-Bromo-4-fluorobenzyl)furan-3-carboxamide2374059-71-7C12H9BrFNO2
- N-(4-Bromo-2-methylbenzyl)furan-3-carboxamide3096348-36-3C13H12BrNO2
- N-(3,5-Dichlorobenzyl)-2-methylfuran-3-carboxamide2794082-66-7C13H11Cl2NO2
- N-(3,4-Dichlorobenzyl)furan-3-carboxamide2321894-41-9C12H9Cl2NO2
- N-(2-Chloro-6-fluorobenzyl)furan-3-carboxamide2325877-67-4C12H9ClFNO2
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(OCc1ccccc1)N1CCCC161 chemicals
O=C(NCc1ccco1)c1ccccc158 chemicals
O=C(Cc1cccs1)Nc1ccccc141 chemicals
O=C(NCC1CCCO1)c1ccccc138 chemicals
O=C(NCC1CCCN1)c1ccccc138 chemicals
O=C(Cc1ccccc1)Nc1nccs137 chemicals
O=S(=O)(NCc1ccco1)c1ccccc136 chemicals
O=S(=O)(NCC1CCCO1)c1ccccc134 chemicals
O=C(NCc1ccccc1)c1ccco130 chemicals
O=C(NCc1ccccc1)c1cccs128 chemicals
c1ccc(CNCc2ccco2)cc128 chemicals![Scaffold O=C(NCc1ccccc1)c1ccc[nH]1](/scaffold/PSYQATYJXPGBDC-UHFFFAOYSA-N/structure.svg)
O=C(NCc1ccccc1)c1ccc[nH]125 chemicals