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Murcko scaffold

2-Cyclobutylthiophene scaffold

317 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 9
Chemicals: 317
With full pages: 6

Scaffold SMILES

c1csc(C2CCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-Cyclobutylthiophene page

Murcko scaffold c1csc(C2CCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 240 of 317 chemicals

2-[1-(Thiophen-2-yl)cyclobutyl]ethan-1-amine chemical structure, C10H15NS, CAS 2229207-02-5

2-[1-(Thiophen-2-yl)cyclobutyl]ethan-1-amine

CAS 2229207-02-5C₁₀H₁₅NS

1-{3,3-Difluoro-1-[5-(trifluoromethyl)thiophen-2-yl]cyclobutyl}methanamine chemical structure, C10H10F5NS, CAS 2228279-54-5

1-{3,3-Difluoro-1-[5-(trifluoromethyl)thiophen-2-yl]cyclobutyl}methanamine

CAS 2228279-54-5C₁₀H₁₀F₅NS

5-(1-Cyanocyclobutyl)thiophene-3-carbonitrile chemical structure, C10H8N2S, CAS 2228707-89-7

5-(1-Cyanocyclobutyl)thiophene-3-carbonitrile

CAS 2228707-89-7C₁₀H₈N₂S

2-[1-(4-Chlorothiophen-2-yl)cyclobutyl]acetic acid chemical structure, C10H11ClO2S, CAS 2228646-85-1

2-[1-(4-Chlorothiophen-2-yl)cyclobutyl]acetic acid

CAS 2228646-85-1C₁₀H₁₁ClO₂S

3-Amino-3-(3-ethylthiophen-2-yl)cyclobutan-1-ol chemical structure, C10H15NOS, CAS 2228525-55-9

3-Amino-3-(3-ethylthiophen-2-yl)cyclobutan-1-ol

CAS 2228525-55-9C₁₀H₁₅NOS

2-[1-(4-Chlorothiophen-2-yl)cyclobutyl]ethan-1-amine chemical structure, C10H14ClNS, CAS 2229230-69-5

2-[1-(4-Chlorothiophen-2-yl)cyclobutyl]ethan-1-amine

CAS 2229230-69-5C₁₀H₁₄ClNS

3-(Aminomethyl)-3-(5-nitrothiophen-2-yl)cyclobutan-1-ol chemical structure, C9H12N2O3S, CAS 2228530-76-3

3-(Aminomethyl)-3-(5-nitrothiophen-2-yl)cyclobutan-1-ol

CAS 2228530-76-3C₉H₁₂N₂O₃S

2-[1-(4-Bromothiophen-2-yl)cyclobutyl]ethan-1-amine chemical structure, C10H14BrNS, CAS 2229015-89-6

2-[1-(4-Bromothiophen-2-yl)cyclobutyl]ethan-1-amine

CAS 2229015-89-6C₁₀H₁₄BrNS

1-[3,3-Difluoro-1-(3-methylthiophen-2-yl)cyclobutyl]methanamine chemical structure, C10H13F2NS, CAS 2229476-95-1

1-[3,3-Difluoro-1-(3-methylthiophen-2-yl)cyclobutyl]methanamine

CAS 2229476-95-1C₁₀H₁₃F₂NS

1-(5-Propylthiophen-2-yl)cyclobutan-1-amine chemical structure, C11H17NS, CAS 2228652-95-5

1-(5-Propylthiophen-2-yl)cyclobutan-1-amine

CAS 2228652-95-5C₁₁H₁₇NS

2-[1-(3-Chlorothiophen-2-yl)cyclobutyl]acetic acid chemical structure, C10H11ClO2S, CAS 2228496-36-2

2-[1-(3-Chlorothiophen-2-yl)cyclobutyl]acetic acid

CAS 2228496-36-2C₁₀H₁₁ClO₂S

3-Amino-3-(4-chlorothiophen-2-yl)cyclobutan-1-ol chemical structure, C8H10ClNOS, CAS 2229031-40-5

3-Amino-3-(4-chlorothiophen-2-yl)cyclobutan-1-ol

CAS 2229031-40-5C₈H₁₀ClNOS

1-[5-(Trifluoromethyl)thiophen-2-yl]cyclobutane-1-carboxylic acid chemical structure, C10H9F3O2S, CAS 2228972-93-6

1-[5-(Trifluoromethyl)thiophen-2-yl]cyclobutane-1-carboxylic acid

CAS 2228972-93-6C₁₀H₉F₃O₂S

3-Amino-3-(4-bromo-5-methylthiophen-2-yl)cyclobutan-1-ol chemical structure, C9H12BrNOS, CAS 2229073-25-8

3-Amino-3-(4-bromo-5-methylthiophen-2-yl)cyclobutan-1-ol

CAS 2229073-25-8C₉H₁₂BrNOS

1-(5-Methylthiophen-2-yl)cyclobutane-1-carbonitrile chemical structure, C10H11NS, CAS 2229499-22-1

1-(5-Methylthiophen-2-yl)cyclobutane-1-carbonitrile

CAS 2229499-22-1C₁₀H₁₁NS

3-(Aminomethyl)-3-(3-chlorothiophen-2-yl)cyclobutan-1-ol chemical structure, C9H12ClNOS, CAS 2228536-43-2

3-(Aminomethyl)-3-(3-chlorothiophen-2-yl)cyclobutan-1-ol

CAS 2228536-43-2C₉H₁₂ClNOS

5-[1-(Aminomethyl)-3-hydroxycyclobutyl]thiophene-3-carbonitrile chemical structure, C10H12N2OS, CAS 2228623-65-0

5-[1-(Aminomethyl)-3-hydroxycyclobutyl]thiophene-3-carbonitrile

CAS 2228623-65-0C₁₀H₁₂N₂OS

5-[1-(Aminomethyl)-3-hydroxycyclobutyl]thiophene-2-carbonitrile chemical structure, C10H12N2OS, CAS 2228213-13-4

5-[1-(Aminomethyl)-3-hydroxycyclobutyl]thiophene-2-carbonitrile

CAS 2228213-13-4C₁₀H₁₂N₂OS

1-(5-Chlorothiophen-2-yl)-3,3-difluorocyclobutan-1-amine chemical structure, C8H8ClF2NS, CAS 2229076-72-4

1-(5-Chlorothiophen-2-yl)-3,3-difluorocyclobutan-1-amine

CAS 2229076-72-4C₈H₈ClF₂NS

3-(Aminomethyl)-3-(5-propylthiophen-2-yl)cyclobutan-1-ol chemical structure, C12H19NOS, CAS 2229516-38-3

3-(Aminomethyl)-3-(5-propylthiophen-2-yl)cyclobutan-1-ol

CAS 2229516-38-3C₁₂H₁₉NOS

Methyl 5-(1-aminocyclobutyl)thiophene-3-carboxylate chemical structure, C10H13NO2S, CAS 2228620-42-4

Methyl 5-(1-aminocyclobutyl)thiophene-3-carboxylate

CAS 2228620-42-4C₁₀H₁₃NO₂S

3-Amino-3-(5-methylthiophen-2-yl)cyclobutan-1-ol chemical structure, C9H13NOS, CAS 2229613-96-9

3-Amino-3-(5-methylthiophen-2-yl)cyclobutan-1-ol

CAS 2229613-96-9C₉H₁₃NOS

1-(5-Propylthiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C12H16O2S, CAS 2229089-58-9

1-(5-Propylthiophen-2-yl)cyclobutane-1-carboxylic acid

CAS 2229089-58-9C₁₂H₁₆O₂S

3-Hydroxy-1-[5-(trifluoromethyl)thiophen-2-yl]cyclobutane-1-carboxylic acid chemical structure, C10H9F3O3S, CAS 2229535-28-6

3-Hydroxy-1-[5-(trifluoromethyl)thiophen-2-yl]cyclobutane-1-carboxylic acid

CAS 2229535-28-6C₁₀H₉F₃O₃S