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Murcko scaffold

2-Cyclobutylthiophene scaffold

317 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 9
Chemicals: 317
With full pages: 6

Scaffold SMILES

c1csc(C2CCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-Cyclobutylthiophene page

Murcko scaffold c1csc(C2CCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 317 chemicals

1-(3-Ethylthiophen-2-yl)-3-hydroxycyclobutane-1-carboxylic acid chemical structure, C11H14O3S, CAS 2228142-11-6

1-(3-Ethylthiophen-2-yl)-3-hydroxycyclobutane-1-carboxylic acid

CAS 2228142-11-6C₁₁H₁₄O₃S

3-Amino-1-(3-methylthiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C10H13NO2S, CAS 2228919-57-9

3-Amino-1-(3-methylthiophen-2-yl)cyclobutane-1-carboxylic acid

CAS 2228919-57-9C₁₀H₁₃NO₂S

3-(Aminomethyl)-3-(4-bromo-5-methylthiophen-2-yl)cyclobutan-1-ol chemical structure, C10H14BrNOS, CAS 2228804-05-3

3-(Aminomethyl)-3-(4-bromo-5-methylthiophen-2-yl)cyclobutan-1-ol

CAS 2228804-05-3C₁₀H₁₄BrNOS

3-Amino-1-(5-propylthiophen-2-yl)cyclobutane-1-carboxylic acid chemical structure, C12H17NO2S, CAS 2228361-55-3

3-Amino-1-(5-propylthiophen-2-yl)cyclobutane-1-carboxylic acid

CAS 2228361-55-3C₁₂H₁₇NO₂S

[1-(4-Bromo-5-methylthiophen-2-yl)cyclobutyl]methanol chemical structure, C10H13BrOS, CAS 2229410-38-0

[1-(4-Bromo-5-methylthiophen-2-yl)cyclobutyl]methanol

CAS 2229410-38-0C₁₀H₁₃BrOS

Methyl 5-[1-(aminomethyl)-3-hydroxycyclobutyl]thiophene-3-carboxylate chemical structure, C11H15NO3S, CAS 2229612-50-2

Methyl 5-[1-(aminomethyl)-3-hydroxycyclobutyl]thiophene-3-carboxylate

CAS 2229612-50-2C₁₁H₁₅NO₃S

[1-(5-Propylthiophen-2-yl)cyclobutyl]methanol chemical structure, C12H18OS, CAS 2228936-47-6

[1-(5-Propylthiophen-2-yl)cyclobutyl]methanol

CAS 2228936-47-6C₁₂H₁₈OS

3-Amino-1-[5-(trifluoromethyl)thiophen-2-yl]cyclobutane-1-carboxylic acid chemical structure, C10H10F3NO2S, CAS 2229509-07-1

3-Amino-1-[5-(trifluoromethyl)thiophen-2-yl]cyclobutane-1-carboxylic acid

CAS 2229509-07-1C₁₀H₁₀F₃NO₂S

1-(4-Bromothiophen-2-yl)-3-hydroxycyclobutane-1-carboxylic acid chemical structure, C9H9BrO3S, CAS 2228942-11-6

1-(4-Bromothiophen-2-yl)-3-hydroxycyclobutane-1-carboxylic acid

CAS 2228942-11-6C₉H₉BrO₃S

2-[1-(5-Bromothiophen-2-yl)cyclobutyl]ethan-1-amine chemical structure, C10H14BrNS, CAS 2229173-13-9

2-[1-(5-Bromothiophen-2-yl)cyclobutyl]ethan-1-amine

CAS 2229173-13-9C₁₀H₁₄BrNS

1-(4-Bromothiophen-2-yl)-3,3-difluorocyclobutan-1-amine chemical structure, C8H8BrF2NS, CAS 2229050-27-3

1-(4-Bromothiophen-2-yl)-3,3-difluorocyclobutan-1-amine

CAS 2229050-27-3C₈H₈BrF₂NS

1-(5-Bromothiophen-2-yl)-3,3-difluorocyclobutan-1-amine chemical structure, C8H8BrF2NS, CAS 2228714-79-0

1-(5-Bromothiophen-2-yl)-3,3-difluorocyclobutan-1-amine

CAS 2228714-79-0C₈H₈BrF₂NS

[1-(3-Bromothiophen-2-yl)-3,3-difluorocyclobutyl]methanamine chemical structure, C9H10BrF2NS, CAS 2229072-94-8

[1-(3-Bromothiophen-2-yl)-3,3-difluorocyclobutyl]methanamine

CAS 2229072-94-8C₉H₁₀BrF₂NS

2-[1-(5-Nitrothiophen-2-yl)cyclobutyl]ethan-1-amine chemical structure, C10H14N2O2S, CAS 2229080-89-9

2-[1-(5-Nitrothiophen-2-yl)cyclobutyl]ethan-1-amine

CAS 2229080-89-9C₁₀H₁₄N₂O₂S

5-(1-Amino-3-hydroxycyclobutyl)thiophene-2-carbonitrile chemical structure, C9H10N2OS, CAS 2229084-68-6

5-(1-Amino-3-hydroxycyclobutyl)thiophene-2-carbonitrile

CAS 2229084-68-6C₉H₁₀N₂OS

2-[1-(3-Methylthiophen-2-yl)cyclobutyl]ethan-1-amine chemical structure, C11H17NS, CAS 2229613-65-2

2-[1-(3-Methylthiophen-2-yl)cyclobutyl]ethan-1-amine

CAS 2229613-65-2C₁₁H₁₇NS

[1-(3-Chloro-4-methylthiophen-2-yl)-3,3-difluorocyclobutyl]methanamine chemical structure, C10H12ClF2NS, CAS 2229417-00-7

[1-(3-Chloro-4-methylthiophen-2-yl)-3,3-difluorocyclobutyl]methanamine

CAS 2229417-00-7C₁₀H₁₂ClF₂NS

5-[1-(2-Aminoethyl)cyclobutyl]thiophene-3-carbonitrile chemical structure, C11H14N2S, CAS 2229164-91-2

5-[1-(2-Aminoethyl)cyclobutyl]thiophene-3-carbonitrile

CAS 2229164-91-2C₁₁H₁₄N₂S

5-(1-Amino-3-hydroxycyclobutyl)thiophene-3-carbonitrile chemical structure, C9H10N2OS, CAS 2229615-31-8

5-(1-Amino-3-hydroxycyclobutyl)thiophene-3-carbonitrile

CAS 2229615-31-8C₉H₁₀N₂OS

Methyl 5-[1-(2-aminoethyl)cyclobutyl]thiophene-2-carboxylate chemical structure, C12H17NO2S, CAS 2229510-62-5

Methyl 5-[1-(2-aminoethyl)cyclobutyl]thiophene-2-carboxylate

CAS 2229510-62-5C₁₂H₁₇NO₂S

5-(1-Cyanocyclobutyl)thiophene-2-carbonitrile chemical structure, C10H8N2S, CAS 2228622-24-8

5-(1-Cyanocyclobutyl)thiophene-2-carbonitrile

CAS 2228622-24-8C₁₀H₈N₂S

1-[4-(Methoxycarbonyl)thiophen-2-yl]cyclobutane-1-carboxylic acid chemical structure, C11H12O4S, CAS 2229423-45-2

1-[4-(Methoxycarbonyl)thiophen-2-yl]cyclobutane-1-carboxylic acid

CAS 2229423-45-2C₁₁H₁₂O₄S

3-(Aminomethyl)-3-(3-ethylthiophen-2-yl)cyclobutan-1-ol chemical structure, C11H17NOS, CAS 2229119-63-3

3-(Aminomethyl)-3-(3-ethylthiophen-2-yl)cyclobutan-1-ol

CAS 2229119-63-3C₁₁H₁₇NOS

5-[1-(Aminomethyl)cyclobutyl]thiophene-2-carbonitrile chemical structure, C10H12N2S, CAS 2228947-36-0

5-[1-(Aminomethyl)cyclobutyl]thiophene-2-carbonitrile

CAS 2228947-36-0C₁₀H₁₂N₂S