Murcko scaffold
Ring system with 3 rings and 18 atoms
663 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 18
- Chemicals
- 663
- With full pages
- 7
Scaffold SMILES
O=C(Nc1cc2c(s1)CNCC2)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 663 chemicals
![6-Acetyl-2-(4-acetylbenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C19H19N3O4S, CAS 864927-62-8](/s/JHRKTZSIXNJRNP-UHFFFAOYSA-N.svg)
6-Acetyl-2-(4-acetylbenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 864927-62-8C19H19N3O4S
![6-Acetyl-2-(2,6-dimethoxybenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C19H21N3O5S, CAS 864928-05-2](/s/FJYMUGBADNVKJH-UHFFFAOYSA-N.svg)
6-Acetyl-2-(2,6-dimethoxybenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 864928-05-2C19H21N3O5S
![Methyl 6-acetyl-2-(2-methoxybenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C19H20N2O5S, CAS 887894-59-9](/s/POXKNLOKFWXWOD-UHFFFAOYSA-N.svg)
Methyl 6-acetyl-2-(2-methoxybenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 887894-59-9C19H20N2O5S
![Methyl 6-acetyl-2-[(4-ethoxybenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate chemical structure, C20H22N2O5S, CAS 921109-37-7](/s/PNZOJKGYAXTMCW-UHFFFAOYSA-N.svg)
Methyl 6-acetyl-2-[(4-ethoxybenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate
CAS 921109-37-7C20H22N2O5S
![Methyl 6-acetyl-2-[(2,6-difluorobenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate chemical structure, C18H16F2N2O4S, CAS 887894-79-3](/s/VXWAKHDAOFAZNU-UHFFFAOYSA-N.svg)
Methyl 6-acetyl-2-[(2,6-difluorobenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate
CAS 887894-79-3C18H16F2N2O4S
![Methyl 6-acetyl-2-(4-isopropoxybenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C21H24N2O5S, CAS 896680-05-0](/s/WIOISWKMEVRASX-UHFFFAOYSA-N.svg)
Methyl 6-acetyl-2-(4-isopropoxybenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 896680-05-0C21H24N2O5S
![Methyl 2-(2-fluorobenzamido)-5,5,7,7-tetramethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C20H23FN2O3S, CAS 887900-86-9](/s/QBTWASZCZSNHPK-UHFFFAOYSA-N.svg)
Methyl 2-(2-fluorobenzamido)-5,5,7,7-tetramethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 887900-86-9C20H23FN2O3S
![Ethyl 6-acetyl-2-(4-(N,N-diethylsulfamoyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C23H29N3O6S2, CAS 449769-31-7](/s/NOLCYFWYZDLOLR-UHFFFAOYSA-N.svg)
Ethyl 6-acetyl-2-(4-(N,N-diethylsulfamoyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 449769-31-7C23H29N3O6S2
![Ethyl 3-cyano-2-[(4-methoxybenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-6-carboxylate chemical structure, C19H19N3O4S, CAS 864926-95-4](/s/KMEZFZZWJASBDP-UHFFFAOYSA-N.svg)
Ethyl 3-cyano-2-[(4-methoxybenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-6-carboxylate
CAS 864926-95-4C19H19N3O4S
![6-Ethyl 3-methyl 2-(4-(N,N-bis(2-methoxyethyl)sulfamoyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate chemical structure, C25H33N3O9S2, CAS 449781-40-2](/s/AREJAVCXLFNSEV-UHFFFAOYSA-N.svg)
6-Ethyl 3-methyl 2-(4-(N,N-bis(2-methoxyethyl)sulfamoyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate
CAS 449781-40-2C25H33N3O9S2
![4-Acetyl-N-(6-acetyl-3-cyano-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl)benzamide chemical structure, C19H17N3O3S, CAS 864858-60-6](/s/APOIXLNMFLUKBB-UHFFFAOYSA-N.svg)
4-Acetyl-N-(6-acetyl-3-cyano-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl)benzamide
CAS 864858-60-6C19H17N3O3S
![N-(3-Cyano-6-isopropyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-4-(N,N-dimethylsulfamoyl)benzamide chemical structure, C20H24N4O3S2, CAS 524683-19-0](/s/UZYYRPMFRHTIRL-UHFFFAOYSA-N.svg)
N-(3-Cyano-6-isopropyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-4-(N,N-dimethylsulfamoyl)benzamide
CAS 524683-19-0C20H24N4O3S2
![N-(6-Acetyl-3-cyano-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-2-fluorobenzamide chemical structure, C17H14FN3O2S, CAS 864858-94-6](/s/JZNGLEQBULMHPG-UHFFFAOYSA-N.svg)
N-(6-Acetyl-3-cyano-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-2-fluorobenzamide
CAS 864858-94-6C17H14FN3O2S
![N-(6-Acetyl-3-cyano-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-4-(tert-butyl)benzamide chemical structure, C21H23N3O2S, CAS 864858-93-5](/s/GXPTUQRJKGDEGO-UHFFFAOYSA-N.svg)
N-(6-Acetyl-3-cyano-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-4-(tert-butyl)benzamide
CAS 864858-93-5C21H23N3O2S
![Methyl 2-[(4-ethoxybenzoyl)amino]-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C22H28N2O4S, CAS 887900-89-2](/s/IGWHJDOUOMICIV-UHFFFAOYSA-N.svg)
Methyl 2-[(4-ethoxybenzoyl)amino]-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxylate
CAS 887900-89-2C22H28N2O4S
![Methyl 2-[(4-chlorobenzoyl)amino]-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C20H23ClN2O3S, CAS 887901-27-1](/s/CRZCOAOMDGJNOQ-UHFFFAOYSA-N.svg)
Methyl 2-[(4-chlorobenzoyl)amino]-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxylate
CAS 887901-27-1C20H23ClN2O3S
![Methyl 4-((6-acetyl-3-carbamoyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)carbamoyl)benzoate chemical structure, C19H19N3O5S, CAS 864927-83-3](/s/XAIHCYURANYGHM-UHFFFAOYSA-N.svg)
Methyl 4-((6-acetyl-3-carbamoyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)carbamoyl)benzoate
CAS 864927-83-3C19H19N3O5S
![6-Acetyl-2-[(2-methoxybenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide chemical structure, C18H19N3O4S, CAS 864927-95-7](/s/BEWNUTREXDBTIY-UHFFFAOYSA-N.svg)
6-Acetyl-2-[(2-methoxybenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide
CAS 864927-95-7C18H19N3O4S
![Ethyl 2-[(4-cyanobenzoyl)amino]-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C22H25N3O3S, CAS 887901-72-6](/s/RUYDKUBHCYFYGZ-UHFFFAOYSA-N.svg)
Ethyl 2-[(4-cyanobenzoyl)amino]-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxylate
CAS 887901-72-6C22H25N3O3S
![Ethyl 2-[(4-acetylbenzoyl)amino]-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C23H28N2O4S, CAS 887901-75-9](/s/WIUMSWBABTYPMU-UHFFFAOYSA-N.svg)
Ethyl 2-[(4-acetylbenzoyl)amino]-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxylate
CAS 887901-75-9C23H28N2O4S
![Methyl 2-[[4-(diethylsulfamoyl)benzoyl]amino]-6-ethyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate chemical structure, C22H29N3O5S2, CAS 449767-29-7](/s/VMKXLJXVPRXWMY-UHFFFAOYSA-N.svg)
Methyl 2-[[4-(diethylsulfamoyl)benzoyl]amino]-6-ethyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate
CAS 449767-29-7C22H29N3O5S2
![6-Acetyl-2-[(4-butoxybenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide chemical structure, C21H25N3O4S, CAS 864927-60-6](/s/FPYMIVADKDALBT-UHFFFAOYSA-N.svg)
6-Acetyl-2-[(4-butoxybenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide
CAS 864927-60-6C21H25N3O4S
![6-Acetyl-2-(3-fluorobenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C17H16FN3O3S, CAS 864927-48-0](/s/GRALIMXVBGPRRH-UHFFFAOYSA-N.svg)
6-Acetyl-2-(3-fluorobenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 864927-48-0C17H16FN3O3S
![N-(6-Acetyl-3-cyano-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-3-butoxybenzamide chemical structure, C21H23N3O3S, CAS 864858-81-1](/s/WTIWWSWUZSFGDR-UHFFFAOYSA-N.svg)
N-(6-Acetyl-3-cyano-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-3-butoxybenzamide
CAS 864858-81-1C21H23N3O3S
- Diethyl 2-(4-(methoxycarbonyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate864926-62-5C22H24N2O7S
- N-(6-Acetyl-3-cyano-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl)-3-bromobenzamide864858-42-4C17H14BrN3O2S
- Methyl 2-[[4-[bis(2-methoxyethyl)sulfamoyl]benzoyl]amino]-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxylate489471-23-0C26H37N3O7S2
- N-(6-Acetyl-3-cyano-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl)-4-fluorobenzamide920451-14-5C17H14FN3O2S
- Ethyl 3-carbamoyl-2-(4-fluorobenzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate864925-64-4C18H18FN3O4S
- Ethyl 2-benzamido-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxylate392673-04-0C21H26N2O3S
- 6-Ethyl 3-methyl 2-(4-methylbenzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate864926-04-5C20H22N2O5S
- N-(6-Acetyl-3-cyano-5,7-dihydro-4H-thieno[2,3-c]pyridin-2-yl)-2,4-dichlorobenzamide864859-20-1C17H13Cl2N3O2S
- N-(6-Acetyl-3-cyano-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-2,6-dimethoxybenzamide864859-08-5C19H19N3O4S
- Ethyl 3-cyano-2-(4-isopropoxybenzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate896680-03-8C21H23N3O4S
- 6-Acetyl-2-(4-ethoxybenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide864927-96-8C19H21N3O4S
- Ethyl 2-benzamido-6-(propan-2-yl)-4H,5H,6H,7H-thieno[2,3-C]pyridine-3-carboxylate74022-36-9C20H24N2O3S
- 6-Ethyl 3-methyl 2-(4-(N,N-dimethylsulfamoyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate449770-42-7C21H25N3O7S2
- Ethyl 2-(4-(N,N-bis(2-methoxyethyl)sulfamoyl)benzamido)-3-carbamoyl-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate449782-29-0C24H32N4O8S2
- Ethyl 2-(4-butoxybenzamido)-3-carbamoyl-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate864925-72-4C22H27N3O5S
- Methyl 2-[[4-(dipropylsulfamoyl)benzoyl]amino]-6-methyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate524679-80-9C23H31N3O5S2
- 6-Acetyl-2-(3,4-dimethoxybenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide864927-66-2C19H21N3O5S
- Ethyl 3-cyano-2-(3,4,5-trimethoxybenzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate864926-96-5C21H23N3O6S
- 5,5,7,7-Tetramethyl-2-(4-methylbenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide887897-93-0C20H25N3O2S
- Methyl 6-acetyl-2-(4-(N-butyl-N-ethylsulfamoyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate449768-97-2C24H31N3O6S2
- 6-Acetyl-2-(3,5-dimethoxybenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide864927-54-8C19H21N3O5S
- 2-(3,4-Dimethoxybenzamido)-5,5,7,7-tetramethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide887898-39-7C21H27N3O4S
- Ethyl 6-acetyl-2-(4-(N-butyl-N-methylsulfamoyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate449769-39-5C24H31N3O6S2
- Diethyl 2-(4-fluorobenzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate864926-45-4C20H21FN2O5S
Related scaffolds
Same ring framework with different atoms or bond orders
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