Murcko scaffold
Ring system with 3 rings and 18 atoms
663 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 18
- Chemicals
- 663
- With full pages
- 7
Scaffold SMILES
O=C(Nc1cc2c(s1)CNCC2)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 97 to 144 of 663 chemicals
![N-(6-Acetyl-3-cyano-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-3-fluorobenzamide chemical structure, C17H14FN3O2S, CAS 864858-38-8](/s/VRFVIMPYPGQAAA-UHFFFAOYSA-N.svg)
N-(6-Acetyl-3-cyano-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-3-fluorobenzamide
CAS 864858-38-8C17H14FN3O2S
![Methyl 6-acetyl-2-(4-(methoxycarbonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C20H20N2O6S, CAS 921109-25-3](/s/QYOWOKLDQFGGBA-UHFFFAOYSA-N.svg)
Methyl 6-acetyl-2-(4-(methoxycarbonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 921109-25-3C20H20N2O6S
![Methyl 6-acetyl-2-[(4-tert-butylbenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate chemical structure, C22H26N2O4S, CAS 887894-49-7](/s/DQJKGQGERLSELH-UHFFFAOYSA-N.svg)
Methyl 6-acetyl-2-[(4-tert-butylbenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate
CAS 887894-49-7C22H26N2O4S
![Ethyl 2-(4-(N,N-diethylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C22H29N3O5S2, CAS 449766-85-2](/s/NEFNUVIJOJAUQP-UHFFFAOYSA-N.svg)
Ethyl 2-(4-(N,N-diethylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 449766-85-2C22H29N3O5S2
![Ethyl 2-(4-(N,N-dipropylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C24H33N3O5S2, CAS 449766-86-3](/s/YJSUUCBSSKVRSY-UHFFFAOYSA-N.svg)
Ethyl 2-(4-(N,N-dipropylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 449766-86-3C24H33N3O5S2
![Ethyl 2-(4-(N-butyl-N-methylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C23H31N3O5S2, CAS 449766-89-6](/s/PIOFVWUIZLASHQ-UHFFFAOYSA-N.svg)
Ethyl 2-(4-(N-butyl-N-methylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 449766-89-6C23H31N3O5S2
![Ethyl 2-(4-(N,N-diallylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C24H29N3O5S2, CAS 449766-93-2](/s/HTLDAVRBPLVVLB-UHFFFAOYSA-N.svg)
Ethyl 2-(4-(N,N-diallylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 449766-93-2C24H29N3O5S2
![2-(4-(N,N-Dimethylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C18H22N4O4S2, CAS 449767-04-8](/s/SFAISODTMVJORG-UHFFFAOYSA-N.svg)
2-(4-(N,N-Dimethylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 449767-04-8C18H22N4O4S2
![2-[[4-(Diethylsulfamoyl)benzoyl]amino]-6-methyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide chemical structure, C20H26N4O4S2, CAS 449767-05-9](/s/DPKUWSCDYSOYKQ-UHFFFAOYSA-N.svg)
2-[[4-(Diethylsulfamoyl)benzoyl]amino]-6-methyl-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide
CAS 449767-05-9C20H26N4O4S2
![2-[(2,5-Dichlorobenzoyl)amino]-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C19H21Cl2N3O2S, CAS 864860-21-9](/s/LKILMFFUPYLZEX-UHFFFAOYSA-N.svg)
2-[(2,5-Dichlorobenzoyl)amino]-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxamide
CAS 864860-21-9C19H21Cl2N3O2S
![Diethyl 2-(4-(N,N-diallylsulfamoyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate chemical structure, C26H31N3O7S2, CAS 449781-62-8](/s/DAWQJCFUDHGDFH-UHFFFAOYSA-N.svg)
Diethyl 2-(4-(N,N-diallylsulfamoyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate
CAS 449781-62-8C26H31N3O7S2
![Methyl 6-acetyl-2-(3-fluorobenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C18H17FN2O4S, CAS 887893-41-6](/s/FUKWMTIIPRFXOK-UHFFFAOYSA-N.svg)
Methyl 6-acetyl-2-(3-fluorobenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 887893-41-6C18H17FN2O4S
![2-(4-(N-Butyl-N-methylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C21H28N4O4S2, CAS 449767-09-3](/s/WYDRECUTEWCEGF-UHFFFAOYSA-N.svg)
2-(4-(N-Butyl-N-methylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 449767-09-3C21H28N4O4S2
![2-(4-(N-Butyl-N-ethylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C22H30N4O4S2, CAS 449767-10-6](/s/IRHXRNBVRZCRHB-UHFFFAOYSA-N.svg)
2-(4-(N-Butyl-N-ethylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 449767-10-6C22H30N4O4S2
![2-(4-(N,N-Diallylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C22H26N4O4S2, CAS 449767-13-9](/s/VRTUOPHLLQGOQY-UHFFFAOYSA-N.svg)
2-(4-(N,N-Diallylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 449767-13-9C22H26N4O4S2
![Ethyl 3-cyano-2-(2-iodobenzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate chemical structure, C18H16IN3O3S, CAS 864927-13-9](/s/MPNWOJICYYPIAZ-UHFFFAOYSA-N.svg)
Ethyl 3-cyano-2-(2-iodobenzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate
CAS 864927-13-9C18H16IN3O3S
![6-Acetyl-2-[(4-pentoxybenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide chemical structure, C22H27N3O4S, CAS 864927-89-9](/s/PDVCZGHXWFIJLF-UHFFFAOYSA-N.svg)
6-Acetyl-2-[(4-pentoxybenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide
CAS 864927-89-9C22H27N3O4S
![2-(4-(N,N-Diethylsulfamoyl)benzamido)-5,5,7,7-tetramethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide chemical structure, C23H32N4O4S2, CAS 489471-25-2](/s/DCESUZAPKDDLSI-UHFFFAOYSA-N.svg)
2-(4-(N,N-Diethylsulfamoyl)benzamido)-5,5,7,7-tetramethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide
CAS 489471-25-2C23H32N4O4S2
![Ethyl 3-cyano-2-(4-(methoxycarbonyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate chemical structure, C20H19N3O5S, CAS 921166-69-0](/s/FUOJESDDMJCCBT-UHFFFAOYSA-N.svg)
Ethyl 3-cyano-2-(4-(methoxycarbonyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate
CAS 921166-69-0C20H19N3O5S
![Ethyl 3-carbamoyl-2-(4-methylbenzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate chemical structure, C19H21N3O4S, CAS 864925-62-2](/s/NMBPVDWVYWSVAD-UHFFFAOYSA-N.svg)
Ethyl 3-carbamoyl-2-(4-methylbenzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate
CAS 864925-62-2C19H21N3O4S
![Methyl 6-acetyl-2-(3-nitrobenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C18H17N3O6S, CAS 921133-03-1](/s/OXSDILKZLVTZJP-UHFFFAOYSA-N.svg)
Methyl 6-acetyl-2-(3-nitrobenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 921133-03-1C18H17N3O6S
![Methyl 2-(4-(N,N-diallylsulfamoyl)benzamido)-6-isopropyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C25H31N3O5S2, CAS 449767-98-0](/s/ZDGPNAJVOLQMHC-UHFFFAOYSA-N.svg)
Methyl 2-(4-(N,N-diallylsulfamoyl)benzamido)-6-isopropyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 449767-98-0C25H31N3O5S2
![Ethyl 3-cyano-2-(2-methoxybenzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate chemical structure, C19H19N3O4S, CAS 864927-07-1](/s/AKSSIZNIDYTYMF-UHFFFAOYSA-N.svg)
Ethyl 3-cyano-2-(2-methoxybenzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate
CAS 864927-07-1C19H19N3O4S
![Methyl 2-(4-(N-butyl-N-methylsulfamoyl)benzamido)-6-ethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate chemical structure, C23H31N3O5S2, CAS 486453-31-0](/s/MTWYQSFAZNAGLB-UHFFFAOYSA-N.svg)
Methyl 2-(4-(N-butyl-N-methylsulfamoyl)benzamido)-6-ethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate
CAS 486453-31-0C23H31N3O5S2
- Methyl 2-(4-(N-butyl-N-ethylsulfamoyl)benzamido)-6-ethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate486453-32-1C24H33N3O5S2
- 6-Acetyl-2-[(3-nitrobenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxamide864927-45-7C17H16N4O5S
- N-(3-Cyano-6-isopropyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-4-(N,N-diethylsulfamoyl)benzamide681182-81-0C22H28N4O3S2
- Ethyl 3-carbamoyl-2-(3-methylbenzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate921135-74-2C19H21N3O4S
- Methyl 6-acetyl-2-(4-(N,N-bis(2-methoxyethyl)sulfamoyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate449769-23-7C24H31N3O8S2
- 2-[(2-Fluorobenzoyl)amino]-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxamide864860-13-9C19H22FN3O2S
- Methyl 2-(4-(N,N-diethylsulfamoyl)benzamido)-6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate486453-07-0C21H27N3O5S2
- Methyl 6-acetyl-2-(4-(N-butyl-N-methylsulfamoyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate449768-95-0C23H29N3O6S2
- 6-Acetyl-2-(2-chlorobenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide864857-76-1C17H16ClN3O3S
- 6-Ethyl 3-methyl 2-(2,6-difluorobenzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate864926-34-1C19H18F2N2O5S
- 6-Acetyl-2-(4-nitrobenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide864927-44-6C17H16N4O5S
- Ethyl 3-cyano-2-(3-nitrobenzamido)-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate864926-91-0C18H16N4O5S
- Diethyl 2-(4-(N-butyl-N-ethylsulfamoyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate449781-56-0C26H35N3O7S2
- Ethyl 2-(4-(N,N-bis(2-cyanoethyl)sulfamoyl)benzamido)-3-carbamoyl-4,5-dihydrothieno[2,3-c]pyridine-6(7H)-carboxylate681437-57-0C24H26N6O6S2
- 6-Ethyl 3-methyl 2-(4-(N,N-diethylsulfamoyl)benzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate449770-44-9C23H29N3O7S2
- 6-Acetyl-2-(4-isopropoxybenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide896680-04-9C20H23N3O4S
- Ethyl 3-cyano-2-[(4-nitrobenzoyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-6-carboxylate864926-90-9C18H16N4O5S
- 6-Ethyl-2-(3,4,5-triethoxybenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide524692-28-2C23H31N3O5S
- 6-Acetyl-2-(4-(N,N-dimethylsulfamoyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide449769-71-5C19H22N4O5S2
- Methyl 2-(4-(N,N-diethylsulfamoyl)benzamido)-5,5,7,7-tetramethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate449782-47-2C24H33N3O5S2
- Methyl 2-[[4-[bis(2-methylpropyl)sulfamoyl]benzoyl]amino]-5,5,7,7-tetramethyl-4,6-dihydrothieno[2,3-c]pyridine-3-carboxylate489471-13-8C28H41N3O5S2
- 6-Acetyl-2-(3,5-dichlorobenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide864857-78-3C17H15Cl2N3O3S
- Diethyl 2-(4-butoxybenzamido)-4,5-dihydrothieno[2,3-c]pyridine-3,6(7H)-dicarboxylate921166-41-8C24H30N2O6S
- 5,5,7,7-Tetramethyl-2-(3-methylbenzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide864860-07-1C20H25N3O2S
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