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Murcko scaffold

Ring system with 2 rings and 16 atoms

8 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
8
With full pages
4
Scaffold SMILES

O=C(NCc1ccccc1)c1c[nH]c(=S)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NCc1ccccc1)c1c[nH]c(=S)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

4-Amino-N-(2-chlorobenzyl)-3-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide chemical structure, C12H12ClN3OS2, CAS 862209-77-6
4-Amino-N-(2-chlorobenzyl)-3-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide
CAS 862209-77-6C12H12ClN3OS2
4-Amino-3-ethyl-2,3-dihydro-N-(phenylmethyl)-2-thioxo-5-thiazolecarboxamide chemical structure, C13H15N3OS2, CAS 618072-01-8
4-Amino-3-ethyl-2,3-dihydro-N-(phenylmethyl)-2-thioxo-5-thiazolecarboxamide
CAS 618072-01-8C13H15N3OS2
3-Allyl-4-amino-N-benzyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide chemical structure, C14H15N3OS2, CAS 618076-60-1
3-Allyl-4-amino-N-benzyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide
CAS 618076-60-1C14H15N3OS2
4-Amino-N-(4-fluorobenzyl)-3-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide chemical structure, C12H12FN3OS2, CAS 849912-25-0
4-Amino-N-(4-fluorobenzyl)-3-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide
CAS 849912-25-0C12H12FN3OS2
4-Amino-N-(4-methoxybenzyl)-3-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide chemical structure, C13H15N3O2S2, CAS 850735-74-9
4-Amino-N-(4-methoxybenzyl)-3-methyl-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide
CAS 850735-74-9C13H15N3O2S2
4-Amino-3-ET-N-(1-phenylethyl)-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide chemical structure, C14H17N3OS2, CAS 618072-07-4
4-Amino-3-ET-N-(1-phenylethyl)-2-thioxo-2,3-dihydro-1,3-thiazole-5-carboxamide
CAS 618072-07-4C14H17N3OS2
3-Allyl-4-amino-N-(2-methoxybenzyl)-2-thioxo-2,3-dihydrothiazole-5-carboxamide chemical structure, C15H17N3O2S2, CAS 946255-09-0
3-Allyl-4-amino-N-(2-methoxybenzyl)-2-thioxo-2,3-dihydrothiazole-5-carboxamide
CAS 946255-09-0C15H17N3O2S2
3-Allyl-4-amino-N-(4-methoxybenzyl)-2-thioxo-2,3-dihydrothiazole-5-carboxamide chemical structure, C15H17N3O2S2, CAS 946331-31-3
3-Allyl-4-amino-N-(4-methoxybenzyl)-2-thioxo-2,3-dihydrothiazole-5-carboxamide
CAS 946331-31-3C15H17N3O2S2