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Murcko scaffold

2,5-Dioxopyrrolidin-1-yl 2-phenylacetate scaffold

30 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
30
With full pages
3
Scaffold SMILES

O=C(Cc1ccccc1)ON1C(=O)CCC1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,5-Dioxopyrrolidin-1-yl 2-phenylacetate page
Murcko scaffold O=C(Cc1ccccc1)ON1C(=O)CCC1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

2,5-Pyrrolidinedione, 1-(((4-nitrophenyl)acetyl)oxy)- chemical structure, C12H10N2O6, CAS 68123-33-1
2,5-Pyrrolidinedione, 1-(((4-nitrophenyl)acetyl)oxy)-
CAS 68123-33-1C12H10N2O6
2,5-Dioxo-1-pyrrolidinyl 4-hydroxy-3-nitrobenzeneacetate chemical structure, C12H10N2O7, CAS 75679-31-1
2,5-Dioxo-1-pyrrolidinyl 4-hydroxy-3-nitrobenzeneacetate
CAS 75679-31-1C12H10N2O7
N-Succinimidyl-2-methoxy 2-phenylacetic acid ester chemical structure, C13H13NO5, CAS 122607-12-9
N-Succinimidyl-2-methoxy 2-phenylacetic acid ester
CAS 122607-12-9C13H13NO5
(((2,5-Dioxopyrrolidin-1-yl)oxy)carbonyl)(4-hydroxyphenyl)acetic acid chemical structure, C13H11NO7, CAS 78641-42-6
(((2,5-Dioxopyrrolidin-1-yl)oxy)carbonyl)(4-hydroxyphenyl)acetic acid
CAS 78641-42-6C13H11NO7
2,5-Dioxopyrrolidin-1-yl 2-phenylbutanoate chemical structure, C14H15NO4, CAS 152683-20-0
2,5-Dioxopyrrolidin-1-yl 2-phenylbutanoate
CAS 152683-20-0C14H15NO4
2,5-Pyrrolidinedione, 1-[2-[4-(2-methylpropyl)phenyl]-1-oxopropoxy]- chemical structure, C17H21NO4, CAS 104400-52-4
2,5-Pyrrolidinedione, 1-[2-[4-(2-methylpropyl)phenyl]-1-oxopropoxy]-
CAS 104400-52-4C17H21NO4
2,5-Dioxopyrrolidin-1-yl 2-(4-(trimethylstannyl)phenyl)acetate chemical structure, C15H19NO4Sn, CAS 156545-12-9
2,5-Dioxopyrrolidin-1-yl 2-(4-(trimethylstannyl)phenyl)acetate
CAS 156545-12-9C15H19NO4Sn
2,5-Dioxopyrrolidin-1-yl 2-phenylacetate chemical structure, C12H11NO4, CAS 23776-85-4
2,5-Dioxopyrrolidin-1-yl 2-phenylacetate
CAS 23776-85-4C12H11NO4
Boc-D-Phg-Osu chemical structure, C17H20N2O6, CAS 39249-27-9
Boc-D-Phg-Osu
CAS 39249-27-9C17H20N2O6
1-{[(2-Fluorophenyl)acetyl]oxy}pyrrolidine-2,5-dione chemical structure, C12H10FNO4, CAS 122630-40-4
1-{[(2-Fluorophenyl)acetyl]oxy}pyrrolidine-2,5-dione
CAS 122630-40-4C12H10FNO4
1-{[(3-Bromophenyl)acetyl]oxy}pyrrolidine-2,5-dione chemical structure, C12H10BrNO4, CAS 122630-39-1
1-{[(3-Bromophenyl)acetyl]oxy}pyrrolidine-2,5-dione
CAS 122630-39-1C12H10BrNO4
2,5-Dioxopyrrolidin-1-yl 2-(4-bromophenyl)acetate chemical structure, C12H10BrNO4, CAS 133611-15-1
2,5-Dioxopyrrolidin-1-yl 2-(4-bromophenyl)acetate
CAS 133611-15-1C12H10BrNO4
1-{[(2-Nitrophenyl)acetyl]oxy}pyrrolidine-2,5-dione chemical structure, C12H10N2O6, CAS 83039-58-1
1-{[(2-Nitrophenyl)acetyl]oxy}pyrrolidine-2,5-dione
CAS 83039-58-1C12H10N2O6
1-{[(3,4-Dimethoxyphenyl)acetyl]oxy}pyrrolidine-2,5-dione chemical structure, C14H15NO6, CAS 67544-77-8
1-{[(3,4-Dimethoxyphenyl)acetyl]oxy}pyrrolidine-2,5-dione
CAS 67544-77-8C14H15NO6
4-Hydroxyphenylacetic acid succinimidyl ester chemical structure, C12H11NO5, CAS 73158-83-5
4-Hydroxyphenylacetic acid succinimidyl ester
CAS 73158-83-5C12H11NO5
2,5-Dioxo-1-pyrrolidinyl 4-azidobenzeneacetate chemical structure, C12H10N4O4, CAS 1017792-15-2
2,5-Dioxo-1-pyrrolidinyl 4-azidobenzeneacetate
CAS 1017792-15-2C12H10N4O4
Boc-L-phenylglycine N-hydroxysuccinimide ester chemical structure, C17H20N2O6, CAS 201152-47-8
Boc-L-phenylglycine N-hydroxysuccinimide ester
CAS 201152-47-8C17H20N2O6
N-(4-{2-[(2,5-Dioxopyrrolidin-1-yl)oxy]-2-oxoethyl}phenyl)octanamide chemical structure, C20H26N2O5, CAS 823780-56-9
N-(4-{2-[(2,5-Dioxopyrrolidin-1-yl)oxy]-2-oxoethyl}phenyl)octanamide
CAS 823780-56-9C20H26N2O5
1-({[4-(2-Bromopropanoyl)phenyl]acetyl}oxy)pyrrolidine-2,5-dione chemical structure, C15H14BrNO5, CAS 90103-00-7
1-({[4-(2-Bromopropanoyl)phenyl]acetyl}oxy)pyrrolidine-2,5-dione
CAS 90103-00-7C15H14BrNO5
1-{[Bromo(phenyl)acetyl]oxy}pyrrolidine-2,5-dione chemical structure, C12H10BrNO4, CAS 594857-18-8
1-{[Bromo(phenyl)acetyl]oxy}pyrrolidine-2,5-dione
CAS 594857-18-8C12H10BrNO4
(4-Fluoro-phenyl)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester chemical structure, C12H10FNO4, CAS 138592-92-4
(4-Fluoro-phenyl)-acetic acid 2,5-dioxo-pyrrolidin-1-yl ester
CAS 138592-92-4C12H10FNO4
2,5-Dioxo-1-pyrrolidinyl 4-(octyloxy)benzeneacetate chemical structure, C20H27NO5, CAS 149414-82-4
2,5-Dioxo-1-pyrrolidinyl 4-(octyloxy)benzeneacetate
CAS 149414-82-4C20H27NO5
2,5-Dioxopyrrolidin-1-yl 2-phenylpropanoate chemical structure, C13H13NO4, CAS 154569-24-1
2,5-Dioxopyrrolidin-1-yl 2-phenylpropanoate
CAS 154569-24-1C13H13NO4
2,5-Dioxopyrrolidin-1-yl 2-(p-tolyl)acetate chemical structure, C13H13NO4, CAS 42309-40-0
2,5-Dioxopyrrolidin-1-yl 2-(p-tolyl)acetate
CAS 42309-40-0C13H13NO4