CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 21 atoms

17 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
17
With full pages
4
Scaffold SMILES

O=C(C=Cc1cccs1)Nc1nc(-c2ccccc2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1cccs1)Nc1nc(-c2ccccc2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

(E)-N-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]-3-thiophen-2-ylprop-2-enamide chemical structure, C16H11FN2OS2, CAS 352679-37-9
(E)-N-[4-(4-Fluorophenyl)-1,3-thiazol-2-yl]-3-thiophen-2-ylprop-2-enamide
CAS 352679-37-9C16H11FN2OS2
(E)-N-(4-Phenyl-1,3-thiazol-2-yl)-3-thiophen-2-ylprop-2-enamide chemical structure, C16H12N2OS2, CAS 1164550-59-7
(E)-N-(4-Phenyl-1,3-thiazol-2-yl)-3-thiophen-2-ylprop-2-enamide
CAS 1164550-59-7C16H12N2OS2
(E)-N-[4-(4-Nitrophenyl)-1,3-thiazol-2-yl]-3-thiophen-2-ylprop-2-enamide chemical structure, C16H11N3O3S2, CAS 544658-40-4
(E)-N-[4-(4-Nitrophenyl)-1,3-thiazol-2-yl]-3-thiophen-2-ylprop-2-enamide
CAS 544658-40-4C16H11N3O3S2
(E)-N-[4-(2,4-Difluorophenyl)-1,3-thiazol-2-yl]-3-thiophen-2-ylprop-2-enamide chemical structure, C16H10F2N2OS2, CAS 546076-61-3
(E)-N-[4-(2,4-Difluorophenyl)-1,3-thiazol-2-yl]-3-thiophen-2-ylprop-2-enamide
CAS 546076-61-3C16H10F2N2OS2
(E)-N-(4-(4-Iodophenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C16H11IN2OS2, CAS 850782-21-7
(E)-N-(4-(4-Iodophenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 850782-21-7C16H11IN2OS2
(E)-N-(4-(4-Ethoxyphenyl)thiazol-2-yl)-3-(5-nitrothiophen-2-yl)acrylamide chemical structure, C18H15N3O4S2, CAS 391896-63-2
(E)-N-(4-(4-Ethoxyphenyl)thiazol-2-yl)-3-(5-nitrothiophen-2-yl)acrylamide
CAS 391896-63-2C18H15N3O4S2
(E)-N-(4-(4-Bromophenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C16H11BrN2OS2, CAS 463358-08-9
(E)-N-(4-(4-Bromophenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 463358-08-9C16H11BrN2OS2
(E)-N-(4-(4-Nitrophenyl)thiazol-2-yl)-3-(5-nitrothiophen-2-yl)acrylamide chemical structure, C16H10N4O5S2, CAS 476319-79-6
(E)-N-(4-(4-Nitrophenyl)thiazol-2-yl)-3-(5-nitrothiophen-2-yl)acrylamide
CAS 476319-79-6C16H10N4O5S2
(E)-N-(4-(4-(tert-Butyl)phenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C20H20N2OS2, CAS 397276-64-1
(E)-N-(4-(4-(tert-Butyl)phenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 397276-64-1C20H20N2OS2
(E)-N-(4-(3,4-Dimethylphenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C18H16N2OS2, CAS 1164494-11-4
(E)-N-(4-(3,4-Dimethylphenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 1164494-11-4C18H16N2OS2
(E)-N-(4-(4-Iodophenyl)thiazol-2-yl)-3-(5-nitrothiophen-2-yl)acrylamide chemical structure, C16H10IN3O3S2, CAS 477547-92-5
(E)-N-(4-(4-Iodophenyl)thiazol-2-yl)-3-(5-nitrothiophen-2-yl)acrylamide
CAS 477547-92-5C16H10IN3O3S2
(E)-N-(4-(3,4-Dimethoxyphenyl)thiazol-2-yl)-3-(5-nitrothiophen-2-yl)acrylamide chemical structure, C18H15N3O5S2, CAS 477547-98-1
(E)-N-(4-(3,4-Dimethoxyphenyl)thiazol-2-yl)-3-(5-nitrothiophen-2-yl)acrylamide
CAS 477547-98-1C18H15N3O5S2
(E)-N-(4-(4-Cyanophenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C17H11N3OS2, CAS 1164478-98-1
(E)-N-(4-(4-Cyanophenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 1164478-98-1C17H11N3OS2
(E)-N-(4-(3,4-Dimethoxyphenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C18H16N2O3S2, CAS 476308-08-4
(E)-N-(4-(3,4-Dimethoxyphenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 476308-08-4C18H16N2O3S2
(E)-N-(4-Mesitylthiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C19H18N2OS2, CAS 1164509-09-4
(E)-N-(4-Mesitylthiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 1164509-09-4C19H18N2OS2
(E)-N-(4-(4-Chlorophenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C16H11ClN2OS2, CAS 392323-04-5
(E)-N-(4-(4-Chlorophenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 392323-04-5C16H11ClN2OS2
(E)-N-(4-(2,4-Dimethoxyphenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide chemical structure, C18H16N2O3S2, CAS 393839-05-9
(E)-N-(4-(2,4-Dimethoxyphenyl)thiazol-2-yl)-3-(thiophen-2-yl)acrylamide
CAS 393839-05-9C18H16N2O3S2