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Murcko scaffold

Ring system with 3 rings and 21 atoms

20 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 21
Chemicals: 20
With full pages: 8

Scaffold SMILES

O=C(CSc1nnc(-c2ccccc2)o1)Nc1ccon1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(CSc1nnc(-c2ccccc2)o1)Nc1ccon1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

2-((5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide chemical structure, C14H11FN4O3S, CAS 460064-02-2

2-((5-(4-Fluorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide

CAS 460064-02-2C₁₄H₁₁FN₄O₃S

N-(5-Methylisoxazol-3-yl)-2-((5-(p-tolyl)-1,3,4-oxadiazol-2-yl)thio)acetamide chemical structure, C15H14N4O3S, CAS 497927-12-5

N-(5-Methylisoxazol-3-yl)-2-((5-(p-tolyl)-1,3,4-oxadiazol-2-yl)thio)acetamide

CAS 497927-12-5C₁₅H₁₄N₄O₃S

2-{[5-(4-Hydroxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(5-methyl-1,2-oxazol-3-yl)acetamide chemical structure, C14H12N4O4S, CAS 562849-47-2

2-{[5-(4-Hydroxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(5-methyl-1,2-oxazol-3-yl)acetamide

CAS 562849-47-2C₁₄H₁₂N₄O₄S

2-((5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide chemical structure, C14H11ClN4O3S, CAS 712319-92-1

2-((5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide

CAS 712319-92-1C₁₄H₁₁ClN₄O₃S

2-((5-(2-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide chemical structure, C15H14N4O4S, CAS 823825-58-7

2-((5-(2-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide

CAS 823825-58-7C₁₅H₁₄N₄O₄S

2-((5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide chemical structure, C15H14N4O4S, CAS 762257-36-3

2-((5-(4-Methoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide

CAS 762257-36-3C₁₅H₁₄N₄O₄S

N-(5-Methyl-1,2-oxazol-3-yl)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide chemical structure, C14H12N4O3S, CAS 763095-64-3

N-(5-Methyl-1,2-oxazol-3-yl)-2-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide

CAS 763095-64-3C₁₄H₁₂N₄O₃S

N-(5-Methyl-1,2-oxazol-3-yl)-2-{[5-(2-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamide chemical structure, C15H14N4O3S, CAS 847475-71-2

N-(5-Methyl-1,2-oxazol-3-yl)-2-{[5-(2-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamide

CAS 847475-71-2C₁₅H₁₄N₄O₃S

N-(5-Methyl-1,2-oxazol-3-yl)-2-{[5-(3-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamide chemical structure, C15H14N4O3S, CAS 850936-76-4

N-(5-Methyl-1,2-oxazol-3-yl)-2-{[5-(3-methylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}acetamide

CAS 850936-76-4C₁₅H₁₄N₄O₃S

2-{[5-(3-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(5-methyl-1,2-oxazol-3-yl)acetamide chemical structure, C15H14N4O4S, CAS 850936-97-9

2-{[5-(3-Methoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(5-methyl-1,2-oxazol-3-yl)acetamide

CAS 850936-97-9C₁₅H₁₄N₄O₄S

2-{[5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(5-methyl-1,2-oxazol-3-yl)acetamide chemical structure, C14H11ClN4O3S, CAS 850937-03-0

2-{[5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(5-methyl-1,2-oxazol-3-yl)acetamide

CAS 850937-03-0C₁₄H₁₁ClN₄O₃S

2-((5-(2-Fluorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide chemical structure, C14H11FN4O3S, CAS 850937-08-5

2-((5-(2-Fluorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide

CAS 850937-08-5C₁₄H₁₁FN₄O₃S

2-((5-(4-Ethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide chemical structure, C16H16N4O4S, CAS 850937-22-3

2-((5-(4-Ethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide

CAS 850937-22-3C₁₆H₁₆N₄O₄S

2-{[5-(3,4-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(5-methyl-3-isoxazolyl)acetamide chemical structure, C16H16N4O5S, CAS 825610-75-1

2-{[5-(3,4-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(5-methyl-3-isoxazolyl)acetamide

CAS 825610-75-1C₁₆H₁₆N₄O₅S

2-((5-(3-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide chemical structure, C14H11ClN4O3S, CAS 850937-61-0

2-((5-(3-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide

CAS 850937-61-0C₁₄H₁₁ClN₄O₃S

2-((5-(4-(tert-Butyl)phenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide chemical structure, C18H20N4O3S, CAS 851129-25-4

2-((5-(4-(tert-Butyl)phenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide

CAS 851129-25-4C₁₈H₂₀N₄O₃S

2-((5-(3,5-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide chemical structure, C16H16N4O5S, CAS 851129-28-7

2-((5-(3,5-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide

CAS 851129-28-7C₁₆H₁₆N₄O₅S

N-(5-Methylisoxazol-3-yl)-2-((5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)acetamide chemical structure, C17H18N4O6S, CAS 851129-33-4

N-(5-Methylisoxazol-3-yl)-2-((5-(3,4,5-trimethoxyphenyl)-1,3,4-oxadiazol-2-yl)thio)acetamide

CAS 851129-33-4C₁₇H₁₈N₄O₆S

2-{[5-(3,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(5-methyl-1,2-oxazol-3-yl)acetamide chemical structure, C16H16N4O3S, CAS 851129-43-6

2-{[5-(3,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(5-methyl-1,2-oxazol-3-yl)acetamide

CAS 851129-43-6C₁₆H₁₆N₄O₃S

2-{[5-(2,5-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(5-methyl-1,2-oxazol-3-yl)acetamide chemical structure, C16H16N4O5S, CAS 851129-71-0

2-{[5-(2,5-Dimethoxyphenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(5-methyl-1,2-oxazol-3-yl)acetamide

CAS 851129-71-0C₁₆H₁₆N₄O₅S