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Murcko scaffold

Ring system with 2 rings and 14 atoms

11 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
11
With full pages
7
Scaffold SMILES

C(=Cc1ccns1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Cc1ccns1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

3-(Methylsulfanyl)-5-[(E)-2-(phenylamino)ethenyl]-1,2-thiazole-4-carbonitrile chemical structure, C13H11N3S2, CAS 338417-45-1
3-(Methylsulfanyl)-5-[(E)-2-(phenylamino)ethenyl]-1,2-thiazole-4-carbonitrile
CAS 338417-45-1C13H11N3S2
3-(Methylsulfanyl)-5-[2-(4-toluidino)vinyl]-4-isothiazolecarbonitrile chemical structure, C14H13N3S2, CAS 1164474-08-1
3-(Methylsulfanyl)-5-[2-(4-toluidino)vinyl]-4-isothiazolecarbonitrile
CAS 1164474-08-1C14H13N3S2
4-({2-[4-Cyano-3-(methylsulfanyl)-5-isothiazolyl]vinyl}amino)benzenecarboxylic acid chemical structure, C14H11N3O2S2, CAS 338751-12-5
4-({2-[4-Cyano-3-(methylsulfanyl)-5-isothiazolyl]vinyl}amino)benzenecarboxylic acid
CAS 338751-12-5C14H11N3O2S2
5-[2-(4-Chloroanilino)vinyl]-3-(methylsulfanyl)-4-isothiazolecarbonitrile chemical structure, C13H10ClN3S2, CAS 1164560-32-0
5-[2-(4-Chloroanilino)vinyl]-3-(methylsulfanyl)-4-isothiazolecarbonitrile
CAS 1164560-32-0C13H10ClN3S2
5-[2-(4-Fluoroanilino)vinyl]-3-(methylsulfanyl)-4-isothiazolecarbonitrile chemical structure, C13H10FN3S2, CAS 338751-14-7
5-[2-(4-Fluoroanilino)vinyl]-3-(methylsulfanyl)-4-isothiazolecarbonitrile
CAS 338751-14-7C13H10FN3S2
5-[2-(3-Chloroanilino)vinyl]-3-(methylsulfanyl)-4-isothiazolecarbonitrile chemical structure, C13H10ClN3S2, CAS 1164507-55-4
5-[2-(3-Chloroanilino)vinyl]-3-(methylsulfanyl)-4-isothiazolecarbonitrile
CAS 1164507-55-4C13H10ClN3S2
3-(Methylsulfanyl)-5-{2-[3-(trifluoromethyl)anilino]vinyl}-4-isothiazolecarbonitrile chemical structure, C14H10F3N3S2, CAS 338751-25-0
3-(Methylsulfanyl)-5-{2-[3-(trifluoromethyl)anilino]vinyl}-4-isothiazolecarbonitrile
CAS 338751-25-0C14H10F3N3S2
5-[2-(3,4-Dimethylanilino)vinyl]-3-(methylsulfanyl)-4-isothiazolecarbonitrile chemical structure, C15H15N3S2, CAS 338751-26-1
5-[2-(3,4-Dimethylanilino)vinyl]-3-(methylsulfanyl)-4-isothiazolecarbonitrile
CAS 338751-26-1C15H15N3S2
5-[2-(3,5-Dichloroanilino)vinyl]-3-(methylsulfanyl)-4-isothiazolecarbonitrile chemical structure, C13H9Cl2N3S2, CAS 338751-27-2
5-[2-(3,5-Dichloroanilino)vinyl]-3-(methylsulfanyl)-4-isothiazolecarbonitrile
CAS 338751-27-2C13H9Cl2N3S2
5-[2-(4-Hydroxy-2-methylanilino)vinyl]-3-(methylsulfanyl)-4-isothiazolecarbonitrile chemical structure, C14H13N3OS2, CAS 338751-30-7
5-[2-(4-Hydroxy-2-methylanilino)vinyl]-3-(methylsulfanyl)-4-isothiazolecarbonitrile
CAS 338751-30-7C14H13N3OS2
5-[2-(2,4-Difluoroanilino)vinyl]-3-(methylsulfanyl)-4-isothiazolecarbonitrile chemical structure, C13H9F2N3S2, CAS 338751-42-1
5-[2-(2,4-Difluoroanilino)vinyl]-3-(methylsulfanyl)-4-isothiazolecarbonitrile
CAS 338751-42-1C13H9F2N3S2