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Murcko scaffold

Ring system with 3 rings and 25 atoms

9 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
9
With full pages
1
Scaffold SMILES

O=C(C=Cc1ccccc1)Nc1ccccc1CCC1CCCCN1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C=Cc1ccccc1)Nc1ccccc1CCC1CCCCN1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

Iferanserin chemical structure, C23H28N2O, CAS 58754-46-4
Iferanserin
CAS 58754-46-4C23H28N2O
(2E)-N-[2-[2-(1-Methyl-2-piperidinyl)ethyl]phenyl]-3-phenyl-2-propenamide chemical structure, C23H28N2O, CAS 951155-18-3
(2E)-N-[2-[2-(1-Methyl-2-piperidinyl)ethyl]phenyl]-3-phenyl-2-propenamide
CAS 951155-18-3C23H28N2O
2'-[2-(1-Methyl-2-piperidyl)ethyl]-cinnamanilide chemical structure, C23H28N2O, CAS 43027-20-9
2'-[2-(1-Methyl-2-piperidyl)ethyl]-cinnamanilide
CAS 43027-20-9C23H28N2O
N-{2-[2-(1-Ethylpiperidin-2-yl)ethyl]phenyl}-3-phenylprop-2-enamide chemical structure, C24H30N2O, CAS 58754-15-7
N-{2-[2-(1-Ethylpiperidin-2-yl)ethyl]phenyl}-3-phenylprop-2-enamide
CAS 58754-15-7C24H30N2O
Iferanserin hydrochloride chemical structure, C23H29ClN2O, CAS 210350-29-1
Iferanserin hydrochloride
CAS 210350-29-1C23H29ClN2O
(2E)-N-[2-[2-(1-Methyl-2-piperidinyl)ethyl]phenyl]-3-(4-hydroxy-3-methoxyphenyl)-2-propenamide chemical structure, C24H30N2O3, CAS 1346606-27-6
(2E)-N-[2-[2-(1-Methyl-2-piperidinyl)ethyl]phenyl]-3-(4-hydroxy-3-methoxyphenyl)-2-propenamide
CAS 1346606-27-6C24H30N2O3
Duloxetine phenyl carbamate (>85%) chemical structure, C23H28N2O2, CAS 1346606-33-4
Duloxetine phenyl carbamate (>85%)
CAS 1346606-33-4C23H28N2O2
(2E)-N-[2-[2-(1-Methyl-2-piperidinyl)ethyl]phenyl]-3-(4-hydroxyphenyl)-2-propenamide-13C,d3 chemical structure, C23H28N2O2, CAS 1346606-61-8
(2E)-N-[2-[2-(1-Methyl-2-piperidinyl)ethyl]phenyl]-3-(4-hydroxyphenyl)-2-propenamide-13C,d3
CAS 1346606-61-8C23H28N2O2
N-(2-{2-[(2R)-1-Methylpiperidin-2-yl]ethyl}phenyl)-3-phenylprop-2-enamide chemical structure, C23H28N2O, CAS 58754-47-5
N-(2-{2-[(2R)-1-Methylpiperidin-2-yl]ethyl}phenyl)-3-phenylprop-2-enamide
CAS 58754-47-5C23H28N2O