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Murcko scaffold

4-(1,3-Thiazol-2-yl)piperidine scaffold

176 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
176
With full pages
16
Scaffold SMILES

c1csc(C2CCNCC2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(1,3-Thiazol-2-yl)piperidine page
Murcko scaffold c1csc(C2CCNCC2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 176 chemicals

2-(2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)-5-methylthiazol-4-yl)acetic acid chemical structure, C16H24N2O4S, CAS 845885-88-3
2-(2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)-5-methylthiazol-4-yl)acetic acid
CAS 845885-88-3C16H24N2O4S
2-(1-((tert-Butoxy)carbonyl)piperidin-4-yl)-1,3-thiazole-4-carboxylic acid chemical structure, C14H20N2O4S, CAS 365413-00-9
2-(1-((tert-Butoxy)carbonyl)piperidin-4-yl)-1,3-thiazole-4-carboxylic acid
CAS 365413-00-9C14H20N2O4S
Ethyl 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)thiazole-4-carboxylate chemical structure, C16H24N2O4S, CAS 365413-31-6
Ethyl 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)thiazole-4-carboxylate
CAS 365413-31-6C16H24N2O4S
2-{1-[(tert-Butoxy)carbonyl]piperidin-4-yl}-4-methyl-1,3-thiazole-5-carboxylic acid chemical structure, C15H22N2O4S, CAS 216955-61-2
2-{1-[(tert-Butoxy)carbonyl]piperidin-4-yl}-4-methyl-1,3-thiazole-5-carboxylic acid
CAS 216955-61-2C15H22N2O4S
tert-Butyl 4-(5-formyl-4-methyl-1,3-thiazol-2-yl)piperidine-1-carboxylate chemical structure, C15H22N2O3S, CAS 850374-97-9
tert-Butyl 4-(5-formyl-4-methyl-1,3-thiazol-2-yl)piperidine-1-carboxylate
CAS 850374-97-9C15H22N2O3S
tert-Butyl 4-[5-(ethoxycarbonyl)-4-methyl-1,3-thiazol-2-yl]tetrahydro-1(2H)-pyridinecarboxylate chemical structure, C17H26N2O4S, CAS 852180-50-8
tert-Butyl 4-[5-(ethoxycarbonyl)-4-methyl-1,3-thiazol-2-yl]tetrahydro-1(2H)-pyridinecarboxylate
CAS 852180-50-8C17H26N2O4S
tert-Butyl 4-[4-(hydroxymethyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate chemical structure, C14H22N2O3S, CAS 864068-79-1
tert-Butyl 4-[4-(hydroxymethyl)-1,3-thiazol-2-yl]piperidine-1-carboxylate
CAS 864068-79-1C14H22N2O3S
tert-Butyl 4-[5-(hydroxymethyl)-4-methyl-1,3-thiazol-2-yl]tetrahydro-1(2H)-pyridinecarboxylate chemical structure, C15H24N2O3S, CAS 857283-66-0
tert-Butyl 4-[5-(hydroxymethyl)-4-methyl-1,3-thiazol-2-yl]tetrahydro-1(2H)-pyridinecarboxylate
CAS 857283-66-0C15H24N2O3S
tert-Butyl 4-(4-formyl-1,3-thiazol-2-yl)piperidine-1-carboxylate chemical structure, C14H20N2O3S, CAS 869901-02-0
tert-Butyl 4-(4-formyl-1,3-thiazol-2-yl)piperidine-1-carboxylate
CAS 869901-02-0C14H20N2O3S
tert-Butyl 4-{4-[(methylamino)methyl]-1,3-thiazol-2-yl}piperidine-1-carboxylate chemical structure, C15H25N3O2S, CAS 869901-03-1
tert-Butyl 4-{4-[(methylamino)methyl]-1,3-thiazol-2-yl}piperidine-1-carboxylate
CAS 869901-03-1C15H25N3O2S
4-(4-tert-Butyl-1,3-thiazol-2-yl)piperidine chemical structure, C12H20N2S, CAS 107507-50-6
4-(4-tert-Butyl-1,3-thiazol-2-yl)piperidine
CAS 107507-50-6C12H20N2S
4-(4-Methyl-1,3-thiazol-2-yl)piperidine chemical structure, C9H14N2S, CAS 933701-74-7
4-(4-Methyl-1,3-thiazol-2-yl)piperidine
CAS 933701-74-7C9H14N2S
4-(1,3-Thiazol-2-yl)piperidine chemical structure, C8H12N2S, CAS 788822-03-7
4-(1,3-Thiazol-2-yl)piperidine
CAS 788822-03-7C8H12N2S
4-(Dimethyl-1,3-thiazol-2-yl)piperidine chemical structure, C10H16N2S, CAS 1004527-71-2
4-(Dimethyl-1,3-thiazol-2-yl)piperidine
CAS 1004527-71-2C10H16N2S
4-(4-Ethyl-1,3-thiazol-2-yl)piperidine chemical structure, C10H16N2S, CAS 1017250-65-5
4-(4-Ethyl-1,3-thiazol-2-yl)piperidine
CAS 1017250-65-5C10H16N2S
4-[4-(Propan-2-yl)-1,3-thiazol-2-yl]piperidine chemical structure, C11H18N2S, CAS 1017184-52-9
4-[4-(Propan-2-yl)-1,3-thiazol-2-yl]piperidine
CAS 1017184-52-9C11H18N2S
2-(Piperidin-4-yl)thiazole-4-carboxylic acid chemical structure, C9H12N2O2S, CAS 1181645-69-1
2-(Piperidin-4-yl)thiazole-4-carboxylic acid
CAS 1181645-69-1C9H12N2O2S
4-Methyl-2-(piperidin-4-yl)thiazole-5-carboxylic acid chemical structure, C10H14N2O2S, CAS 1181583-58-3
4-Methyl-2-(piperidin-4-yl)thiazole-5-carboxylic acid
CAS 1181583-58-3C10H14N2O2S
2-(2-(Piperidin-4-yl)thiazol-4-yl)acetic acid chemical structure, C10H14N2O2S, CAS 1181412-65-6
2-(2-(Piperidin-4-yl)thiazol-4-yl)acetic acid
CAS 1181412-65-6C10H14N2O2S
2-(1-Acetylpiperidin-4-yl)-1,3-thiazole-4-carboxylic acid chemical structure, C11H14N2O3S, CAS 1181793-52-1
2-(1-Acetylpiperidin-4-yl)-1,3-thiazole-4-carboxylic acid
CAS 1181793-52-1C11H14N2O3S
2-[2-(1-Acetylpiperidin-4-yl)-1,3-thiazol-4-yl]acetic acid chemical structure, C12H16N2O3S, CAS 1181981-23-6
2-[2-(1-Acetylpiperidin-4-yl)-1,3-thiazol-4-yl]acetic acid
CAS 1181981-23-6C12H16N2O3S
2-(1-Acetylpiperidin-4-yl)-4-methyl-1,3-thiazole-5-carboxylic acid chemical structure, C12H16N2O3S, CAS 1181701-72-3
2-(1-Acetylpiperidin-4-yl)-4-methyl-1,3-thiazole-5-carboxylic acid
CAS 1181701-72-3C12H16N2O3S
2-(2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)thiazol-4-yl)acetic acid chemical structure, C15H22N2O4S, CAS 1000991-57-0
2-(2-(1-(tert-Butoxycarbonyl)piperidin-4-yl)thiazol-4-yl)acetic acid
CAS 1000991-57-0C15H22N2O4S
4-Bromo-2-(piperidin-4-yl)thiazole chemical structure, C8H11BrN2S, CAS 1159815-51-6
4-Bromo-2-(piperidin-4-yl)thiazole
CAS 1159815-51-6C8H11BrN2S