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Murcko scaffold

4-(1,3-Thiazol-2-yl)piperidine scaffold

176 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
176
With full pages
16
Scaffold SMILES

c1csc(C2CCNCC2)n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(1,3-Thiazol-2-yl)piperidine page
Murcko scaffold c1csc(C2CCNCC2)n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 176 chemicals

4-(4-(Trifluoromethyl)-1,3-thiazol-2-yl)piperidine chemical structure, C9H11F3N2S, CAS 1248983-30-3
4-(4-(Trifluoromethyl)-1,3-thiazol-2-yl)piperidine
CAS 1248983-30-3C9H11F3N2S
4-(5-Methyl-1,3-thiazol-2-yl)piperidine chemical structure, C9H14N2S, CAS 1249151-01-6
4-(5-Methyl-1,3-thiazol-2-yl)piperidine
CAS 1249151-01-6C9H14N2S
4-Methyl-4-(1,3-thiazol-2-yl)piperidine chemical structure, C9H14N2S, CAS 1567100-93-9
4-Methyl-4-(1,3-thiazol-2-yl)piperidine
CAS 1567100-93-9C9H14N2S
Methyl 2-(2-(piperidin-4-yl)thiazol-4-yl)acetate chemical structure, C11H16N2O2S, CAS 1495391-70-2
Methyl 2-(2-(piperidin-4-yl)thiazol-4-yl)acetate
CAS 1495391-70-2C11H16N2O2S
Ethyl 4-methyl-2-(piperidin-4-yl)-1,3-thiazole-5-carboxylate chemical structure, C12H18N2O2S, CAS 1211534-10-9
Ethyl 4-methyl-2-(piperidin-4-yl)-1,3-thiazole-5-carboxylate
CAS 1211534-10-9C12H18N2O2S
tert-Butyl 4-(5-bromo-4-methylthiazol-2-yl)piperidine-1-carboxylate chemical structure, C14H21BrN2O2S, CAS 1361116-63-3
tert-Butyl 4-(5-bromo-4-methylthiazol-2-yl)piperidine-1-carboxylate
CAS 1361116-63-3C14H21BrN2O2S
5-Bromo-2-(1-isopropylpiperidin-4-yl)-4-methylthiazole chemical structure, C12H19BrN2S, CAS 1361116-64-4
5-Bromo-2-(1-isopropylpiperidin-4-yl)-4-methylthiazole
CAS 1361116-64-4C12H19BrN2S
1-(4-(5-Bromo-4-methylthiazol-2-yl)piperidin-1-yl)ethanone chemical structure, C11H15BrN2OS, CAS 1361113-49-6
1-(4-(5-Bromo-4-methylthiazol-2-yl)piperidin-1-yl)ethanone
CAS 1361113-49-6C11H15BrN2OS
5-Bromo-4-methyl-2-(1-(methylsulfonyl)piperidin-4-yl)thiazole chemical structure, C10H15BrN2O2S2, CAS 1361115-05-0
5-Bromo-4-methyl-2-(1-(methylsulfonyl)piperidin-4-yl)thiazole
CAS 1361115-05-0C10H15BrN2O2S2
tert-Butyl 4-(4-bromo-1,3-thiazol-2-yl)-4-hydroxypiperidine-1-carboxylate chemical structure, C13H19BrN2O3S, CAS 1313009-82-3
tert-Butyl 4-(4-bromo-1,3-thiazol-2-yl)-4-hydroxypiperidine-1-carboxylate
CAS 1313009-82-3C13H19BrN2O3S
tert-Butyl 4-(4-bromo-1,3-thiazol-2-yl)-4-fluoropiperidine-1-carboxylate chemical structure, C13H18BrFN2O2S, CAS 1313009-83-4
tert-Butyl 4-(4-bromo-1,3-thiazol-2-yl)-4-fluoropiperidine-1-carboxylate
CAS 1313009-83-4C13H18BrFN2O2S
4-(4-Hydroxymethyl-5-methyl-thiazol-2-yl)-piperidine-1-carboxylic acid tert-butyl ester chemical structure, C15H24N2O3S, CAS 1037798-30-3
4-(4-Hydroxymethyl-5-methyl-thiazol-2-yl)-piperidine-1-carboxylic acid tert-butyl ester
CAS 1037798-30-3C15H24N2O3S
Ethyl 2-(4-piperidinyl)-4-thiazolecarboxylate monohydrochloride chemical structure, C11H17ClN2O2S, CAS 922516-41-4
Ethyl 2-(4-piperidinyl)-4-thiazolecarboxylate monohydrochloride
CAS 922516-41-4C11H17ClN2O2S
4-(1,3-Thiazol-2-yl)piperidine hydrochloride chemical structure, C8H13ClN2S, CAS 690262-03-4
4-(1,3-Thiazol-2-yl)piperidine hydrochloride
CAS 690262-03-4C8H13ClN2S
1,1-Dimethylethyl 4-(4-ethenyl-2-thiazolyl)-1-piperidinecarboxylate chemical structure, C15H22N2O2S, CAS 1003320-06-6
1,1-Dimethylethyl 4-(4-ethenyl-2-thiazolyl)-1-piperidinecarboxylate
CAS 1003320-06-6C15H22N2O2S
4-Amino-2-(N-boc-piperidin-4-yl)thiazole chemical structure, C13H21N3O2S, CAS 1416725-84-2
4-Amino-2-(N-boc-piperidin-4-yl)thiazole
CAS 1416725-84-2C13H21N3O2S
tert-Butyl N-[2-(piperidin-4-yl)-1,3-thiazol-4-yl]carbamate chemical structure, C13H21N3O2S, CAS 1690538-89-6
tert-Butyl N-[2-(piperidin-4-yl)-1,3-thiazol-4-yl]carbamate
CAS 1690538-89-6C13H21N3O2S
2-(Piperidin-4-yl)thiazole-4-carbaldehyde chemical structure, C9H12N2OS, CAS 1003639-36-8
2-(Piperidin-4-yl)thiazole-4-carbaldehyde
CAS 1003639-36-8C9H12N2OS
Ethyl 2-(piperidin-4-yl)-4-(trifluoromethyl)thiazole-5-carboxylate chemical structure, C12H15F3N2O2S, CAS 1211525-43-7
Ethyl 2-(piperidin-4-yl)-4-(trifluoromethyl)thiazole-5-carboxylate
CAS 1211525-43-7C12H15F3N2O2S
5-Bromo-4-methyl-2-(piperidin-4-yl)thiazole chemical structure, C9H13BrN2S, CAS 1211586-30-9
5-Bromo-4-methyl-2-(piperidin-4-yl)thiazole
CAS 1211586-30-9C9H13BrN2S
4-(4-Formyl-1,3-thiazol-2-yl)piperidinium chloride chemical structure, C9H13ClN2OS, CAS 1003320-03-3
4-(4-Formyl-1,3-thiazol-2-yl)piperidinium chloride
CAS 1003320-03-3C9H13ClN2OS
tert-Butyl 4-(4-[(hydroxyimino)methyl]-1,3-thiazol-2-yl)piperidine-1-carboxylate chemical structure, C14H21N3O3S, CAS 1313010-11-5
tert-Butyl 4-(4-[(hydroxyimino)methyl]-1,3-thiazol-2-yl)piperidine-1-carboxylate
CAS 1313010-11-5C14H21N3O3S
tert-Butyl 4-fluoro-4-(4-formyl-1,3-thiazol-2-yl)piperidine-1-carboxylate chemical structure, C14H19FN2O3S, CAS 1313009-84-5
tert-Butyl 4-fluoro-4-(4-formyl-1,3-thiazol-2-yl)piperidine-1-carboxylate
CAS 1313009-84-5C14H19FN2O3S
Ethyl 2-(piperidin-4-yl)-1,3-thiazole-5-carboxylate chemical structure, C11H16N2O2S, CAS 1488388-39-1
Ethyl 2-(piperidin-4-yl)-1,3-thiazole-5-carboxylate
CAS 1488388-39-1C11H16N2O2S