CompoundList
Murcko scaffold

Alpha-Methylene butyrolactone scaffold

127 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
7
Chemicals
127
With full pages
17
Scaffold SMILES

C=C1CCOC1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Murcko scaffold C=C1CCOC1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 127 chemicals

(+)-Protolichesteric acid chemical structure, C19H32O4
(+)-Protolichesteric acid
C19H32O4
alpha-Methylene butyrolactone chemical structure, C5H6O2, CAS 547-65-9
alpha-Methylene butyrolactone
CAS 547-65-9C5H6O2
gamma-Methyl-alpha-methylene-gamma-butyrolactone chemical structure, C6H8O2, CAS 62873-16-9
gamma-Methyl-alpha-methylene-gamma-butyrolactone
CAS 62873-16-9C6H8O2
Methylenolactocin chemical structure, C11H16O4, CAS 112923-53-2
Methylenolactocin
CAS 112923-53-2C11H16O4
Tulipalin B chemical structure, C5H6O3, CAS 38965-80-9
Tulipalin B
CAS 38965-80-9C5H6O3
((2S,3S)-2-Methyl-4-methylidene-5-oxo-oxolan-3-yl) acetate chemical structure, C8H10O4, CAS 73738-74-6
((2S,3S)-2-Methyl-4-methylidene-5-oxo-oxolan-3-yl) acetate
CAS 73738-74-6C8H10O4
(2-Ethyl-4-methylidene-5-oxo-oxolan-3-yl) acetate chemical structure, C9H12O4, CAS 76299-61-1
(2-Ethyl-4-methylidene-5-oxo-oxolan-3-yl) acetate
CAS 76299-61-1C9H12O4
2(3H)-Furanone, 4-(acetyloxy)dihydro-3-methylene-5-(1-methylethyl)- chemical structure, C10H14O4, CAS 76299-62-2
2(3H)-Furanone, 4-(acetyloxy)dihydro-3-methylene-5-(1-methylethyl)-
CAS 76299-62-2C10H14O4
(4-Methylidene-5-oxo-2-pentyloxolan-3-yl) acetate chemical structure, C12H18O4, CAS 76299-63-3
(4-Methylidene-5-oxo-2-pentyloxolan-3-yl) acetate
CAS 76299-63-3C12H18O4
((2R,3S)-2-Methyl-4-methylidene-5-oxooxolan-3-yl) acetate chemical structure, C8H10O4, CAS 73738-75-7
((2R,3S)-2-Methyl-4-methylidene-5-oxooxolan-3-yl) acetate
CAS 73738-75-7C8H10O4
2(3H)-Furanone, 4-(acetyloxy)dihydro-3-methylene- chemical structure, C7H8O4, CAS 73738-80-4
2(3H)-Furanone, 4-(acetyloxy)dihydro-3-methylene-
CAS 73738-80-4C7H8O4
2(3H)-Furanone, dihydro-5-(1-methylethyl)-3-(1-methylethylidene)- chemical structure, C10H16O2, CAS 62687-41-6
2(3H)-Furanone, dihydro-5-(1-methylethyl)-3-(1-methylethylidene)-
CAS 62687-41-6C10H16O2
Murolic acid chemical structure, C21H36O5, CAS 70579-58-7
Murolic acid
CAS 70579-58-7C21H36O5
Protoconstipatic acid chemical structure, C21H36O5, CAS 73036-29-0
Protoconstipatic acid
CAS 73036-29-0C21H36O5
4-Methylidene-5-oxo-2-tridecyloxolane-3-carboxylic acid chemical structure, C19H32O4, CAS 1448-96-0
4-Methylidene-5-oxo-2-tridecyloxolane-3-carboxylic acid
CAS 1448-96-0C19H32O4
3-Furoic acid, tetrahydro-4-methylene-5-oxo- chemical structure, C6H6O4, CAS 93913-58-7
3-Furoic acid, tetrahydro-4-methylene-5-oxo-
CAS 93913-58-7C6H6O4
Diethyl 4-methylidene-5-oxooxolane-3,3-dicarboxylate chemical structure, C11H14O6, CAS 56643-56-2
Diethyl 4-methylidene-5-oxooxolane-3,3-dicarboxylate
CAS 56643-56-2C11H14O6
2(3H)-Furanone, dihydro-3-[(methylamino)methylene]-, (3E)- chemical structure, C6H9NO2, CAS 168417-24-1
2(3H)-Furanone, dihydro-3-[(methylamino)methylene]-, (3E)-
CAS 168417-24-1C6H9NO2
2(3H)-Furanone, 3-[(dimethylamino)methylene]-5-hexyldihydro- chemical structure, C13H23NO2, CAS 62527-58-6
2(3H)-Furanone, 3-[(dimethylamino)methylene]-5-hexyldihydro-
CAS 62527-58-6C13H23NO2
(2-Oxooxolan-3-ylidene)methyl methanesulfonate chemical structure, C6H8O5S, CAS 113982-63-1
(2-Oxooxolan-3-ylidene)methyl methanesulfonate
CAS 113982-63-1C6H8O5S
AG-G-81985 chemical structure, C11H14O6, CAS 71817-25-9
AG-G-81985
CAS 71817-25-9C11H14O6
2-(4,4-Dimethyl-2-oxooxolan-3-ylidene)propanedinitrile chemical structure, C9H8N2O2, CAS 82698-94-0
2-(4,4-Dimethyl-2-oxooxolan-3-ylidene)propanedinitrile
CAS 82698-94-0C9H8N2O2
Methyl 2-cyano-2-(4,4-dimethyl-2-oxo-oxolan-3-ylidene)acetate chemical structure, C10H11NO4, CAS 82698-90-6
Methyl 2-cyano-2-(4,4-dimethyl-2-oxo-oxolan-3-ylidene)acetate
CAS 82698-90-6C10H11NO4
Dimethyl 2-(4-ethyl-4-methyl-2-oxooxolan-3-ylidene)propanedioate chemical structure, C12H16O6, CAS 82698-88-2
Dimethyl 2-(4-ethyl-4-methyl-2-oxooxolan-3-ylidene)propanedioate
CAS 82698-88-2C12H16O6