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Murcko scaffold

Ring system with 3 rings and 20 atoms

23 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
23
With full pages
20
Scaffold SMILES

S=c1[nH]nc(C2CCCCC2)n1N=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold S=c1[nH]nc(C2CCCCC2)n1N=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

2-[(1Z)-2-(5-Cyclohexyl-3-sulfanyl(1,2,4-triazol-4-yl))-2-azavinyl]-6-methoxyp henol chemical structure, C16H20N4O2S
2-[(1Z)-2-(5-Cyclohexyl-3-sulfanyl(1,2,4-triazol-4-yl))-2-azavinyl]-6-methoxyp henol
C16H20N4O2S
3-Cyclohexyl-4-[(E)-(4-fluorophenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C15H17FN4S, CAS 488803-54-9
3-Cyclohexyl-4-[(E)-(4-fluorophenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 488803-54-9C15H17FN4S
3-Cyclohexyl-4-[(E)-(3-fluorophenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C15H17FN4S, CAS 500106-73-0
3-Cyclohexyl-4-[(E)-(3-fluorophenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 500106-73-0C15H17FN4S
3-Cyclohexyl-4-[(E)-(2-fluorophenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C15H17FN4S, CAS 489442-68-4
3-Cyclohexyl-4-[(E)-(2-fluorophenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 489442-68-4C15H17FN4S
4-[(E)-(3-Cyclohexyl-5-sulfanylidene-1H-1,2,4-triazol-4-yl)iminomethyl]benzoic acid chemical structure, C16H18N4O2S, CAS 613247-19-1
4-[(E)-(3-Cyclohexyl-5-sulfanylidene-1H-1,2,4-triazol-4-yl)iminomethyl]benzoic acid
CAS 613247-19-1C16H18N4O2S
3-Cyclohexyl-4-[(E)-(4-ethylphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C17H22N4S, CAS 488811-39-8
3-Cyclohexyl-4-[(E)-(4-ethylphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 488811-39-8C17H22N4S
3-Cyclohexyl-4-[(E)-(3-methoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C16H20N4OS, CAS 488103-04-4
3-Cyclohexyl-4-[(E)-(3-methoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 488103-04-4C16H20N4OS
5-Cyclohexyl-4-((4-(dimethylamino)benzylidene)amino)-4H-1,2,4-triazole-3-thiol chemical structure, C17H23N5S, CAS 488119-00-2
5-Cyclohexyl-4-((4-(dimethylamino)benzylidene)amino)-4H-1,2,4-triazole-3-thiol
CAS 488119-00-2C17H23N5S
4-[(E)-Benzylideneamino]-3-cyclohexyl-1H-1,2,4-triazole-5-thione chemical structure, C15H18N4S, CAS 487038-39-1
4-[(E)-Benzylideneamino]-3-cyclohexyl-1H-1,2,4-triazole-5-thione
CAS 487038-39-1C15H18N4S
3-Cyclohexyl-4-[(E)-(2-ethoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C17H22N4OS, CAS 487038-74-4
3-Cyclohexyl-4-[(E)-(2-ethoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 487038-74-4C17H22N4OS
3-Cyclohexyl-4-[(E)-(2-methylphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C16H20N4S, CAS 488724-42-1
3-Cyclohexyl-4-[(E)-(2-methylphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 488724-42-1C16H20N4S
3-Cyclohexyl-4-[(E)-(4-ethoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C17H22N4OS, CAS 500271-21-6
3-Cyclohexyl-4-[(E)-(4-ethoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 500271-21-6C17H22N4OS
4-[(E)-(2-Chlorophenyl)methylideneamino]-3-cyclohexyl-1H-1,2,4-triazole-5-thione chemical structure, C15H17ClN4S, CAS 500278-86-4
4-[(E)-(2-Chlorophenyl)methylideneamino]-3-cyclohexyl-1H-1,2,4-triazole-5-thione
CAS 500278-86-4C15H17ClN4S
2-[(E)-(3-Cyclohexyl-5-sulfanylidene-1H-1,2,4-triazol-4-yl)iminomethyl]benzoic acid chemical structure, C16H18N4O2S, CAS 613247-21-5
2-[(E)-(3-Cyclohexyl-5-sulfanylidene-1H-1,2,4-triazol-4-yl)iminomethyl]benzoic acid
CAS 613247-21-5C16H18N4O2S
3-Cyclohexyl-4-[(E)-(2,4,6-trimethoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C18H24N4O3S, CAS 489425-31-2
3-Cyclohexyl-4-[(E)-(2,4,6-trimethoxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 489425-31-2C18H24N4O3S
3-Cyclohexyl-4-[(E)-(3-hydroxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C15H18N4OS, CAS 500104-73-4
3-Cyclohexyl-4-[(E)-(3-hydroxyphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 500104-73-4C15H18N4OS
3-Cyclohexyl-4-[(E)-[2-(trifluoromethyl)phenyl]methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C16H17F3N4S, CAS 497943-09-6
3-Cyclohexyl-4-[(E)-[2-(trifluoromethyl)phenyl]methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 497943-09-6C16H17F3N4S
3-Cyclohexyl-4-[(E)-(3-methylphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione chemical structure, C16H20N4S, CAS 488732-71-4
3-Cyclohexyl-4-[(E)-(3-methylphenyl)methylideneamino]-1H-1,2,4-triazole-5-thione
CAS 488732-71-4C16H20N4S
(2-(((3-Cyclohexyl-5-mercapto-4H-1,2,4-triazol-4-yl)imino)ME)phenoxy)acetic acid chemical structure, C17H20N4O3S, CAS 478253-65-5
(2-(((3-Cyclohexyl-5-mercapto-4H-1,2,4-triazol-4-yl)imino)ME)phenoxy)acetic acid
CAS 478253-65-5C17H20N4O3S
4-(((3-Cyclohexyl-5-mercapto-4H-1,2,4-triazol-4-yl)imino)ME)-2,6-dimethoxyphenol chemical structure, C17H22N4O3S, CAS 478253-67-7
4-(((3-Cyclohexyl-5-mercapto-4H-1,2,4-triazol-4-yl)imino)ME)-2,6-dimethoxyphenol
CAS 478253-67-7C17H22N4O3S
(6E)-6-[[(3-Cyclohexyl-5-sulfanylidene-1H-1,2,4-triazol-4-yl)amino]methylidene]-2-methoxycyclohexa-2,4-dien-1-one chemical structure, C16H20N4O2S, CAS 488135-41-7
(6E)-6-[[(3-Cyclohexyl-5-sulfanylidene-1H-1,2,4-triazol-4-yl)amino]methylidene]-2-methoxycyclohexa-2,4-dien-1-one
CAS 488135-41-7C16H20N4O2S
2-{[(3-Cyclohexyl-5-sulfanyl-4H-1,2,4-triazol-4-yl)imino]methyl}-6-ethoxyphenol chemical structure, C17H22N4O2S, CAS 5685-64-3
2-{[(3-Cyclohexyl-5-sulfanyl-4H-1,2,4-triazol-4-yl)imino]methyl}-6-ethoxyphenol
CAS 5685-64-3C17H22N4O2S
4-(((3-Cyclohexyl-5-mercapto-4H-1,2,4-triazol-4-yl)imino)methyl)-1,3-benzenediol chemical structure, C15H18N4O2S, CAS 488096-96-4
4-(((3-Cyclohexyl-5-mercapto-4H-1,2,4-triazol-4-yl)imino)methyl)-1,3-benzenediol
CAS 488096-96-4C15H18N4O2S