Murcko scaffold
Ring system with 4 rings and 22 atoms
840 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 22
- Chemicals
- 840
- With full pages
- 15
Scaffold SMILES
O=C(NC1CCC1)OCC1c2ccccc2-c2ccccc21
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 433 to 480 of 840 chemicals
![(2S,3R)-2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-methoxybutanoic acid chemical structure, C26H30N2O6, CAS 2171201-39-9](/s/ZJQUEVBWJPGQFZ-MWTRTKDXSA-N.svg)
(2S,3R)-2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-methoxybutanoic acid
CAS 2171201-39-9C26H30N2O6
![3-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4,4-difluorobutanoic acid chemical structure, C25H26F2N2O5, CAS 2172288-37-6](/s/GGCMDIFFFVEQPX-UHFFFAOYSA-N.svg)
3-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4,4-difluorobutanoic acid
CAS 2172288-37-6C25H26F2N2O5
![3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4,4-difluorobutanoic acid chemical structure, C25H26F2N2O5, CAS 2172568-52-2](/s/BRRKBBXGGGLYRE-UHFFFAOYSA-N.svg)
3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4,4-difluorobutanoic acid
CAS 2172568-52-2C25H26F2N2O5
![5-{N-Ethyl-1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}pentanoic acid chemical structure, C27H32N2O5, CAS 2171161-88-7](/s/GFVJSXGFLWTQCX-UHFFFAOYSA-N.svg)
5-{N-Ethyl-1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}pentanoic acid
CAS 2171161-88-7C27H32N2O5
![5-{N-Ethyl-2-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}pentanoic acid chemical structure, C28H34N2O5, CAS 2171841-61-3](/s/JYSGDCMYZSSLSC-UHFFFAOYSA-N.svg)
5-{N-Ethyl-2-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}pentanoic acid
CAS 2171841-61-3C28H34N2O5
![4-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-hydroxybutanoic acid chemical structure, C25H28N2O6, CAS 2172245-61-1](/s/VQXVQROYVNWKTL-UHFFFAOYSA-N.svg)
4-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-hydroxybutanoic acid
CAS 2172245-61-1C25H28N2O6
![(2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-methylbutanoic acid chemical structure, C26H30N2O5, CAS 2171151-46-3](/s/LBEGXTHHXNVCTG-DFSZNTFHSA-N.svg)
(2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-methylbutanoic acid
CAS 2171151-46-3C26H30N2O5
![3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2,2-difluoropropanoic acid chemical structure, C24H24F2N2O5, CAS 2172050-88-1](/s/POESDBLSZBGXHS-UHFFFAOYSA-N.svg)
3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2,2-difluoropropanoic acid
CAS 2172050-88-1C24H24F2N2O5
![2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3,3-dimethylbutanoic acid chemical structure, C27H32N2O5, CAS 2171717-49-8](/s/BVJRZWIOIOCPKN-UHFFFAOYSA-N.svg)
2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3,3-dimethylbutanoic acid
CAS 2171717-49-8C27H32N2O5
![(2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}hexanoic acid chemical structure, C27H32N2O5, CAS 2171177-56-1](/s/ASTSVPDXBXHKDL-XCNDVJPKSA-N.svg)
(2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}hexanoic acid
CAS 2171177-56-1C27H32N2O5
![3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4-methylpentanoic acid chemical structure, C27H32N2O5, CAS 2172545-11-6](/s/VNUGVUHHRLIXLO-UHFFFAOYSA-N.svg)
3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4-methylpentanoic acid
CAS 2172545-11-6C27H32N2O5
![2-({2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}methyl)-2-methylbutanoic acid chemical structure, C27H32N2O5, CAS 2172266-51-0](/s/XWHIOTAJKQWQKT-UHFFFAOYSA-N.svg)
2-({2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}methyl)-2-methylbutanoic acid
CAS 2172266-51-0C27H32N2O5
![(2R)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3,3-dimethylbutanoic acid chemical structure, C27H32N2O5, CAS 2171156-21-9](/s/BVJRZWIOIOCPKN-DFSZNTFHSA-N.svg)
(2R)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3,3-dimethylbutanoic acid
CAS 2171156-21-9C27H32N2O5
![4-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-hydroxy-3-methylbutanoic acid chemical structure, C26H30N2O6, CAS 2172025-14-6](/s/SZQRRMRHXCKGIQ-UHFFFAOYSA-N.svg)
4-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-hydroxy-3-methylbutanoic acid
CAS 2172025-14-6C26H30N2O6
![3-(2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}ethoxy)propanoic acid chemical structure, C26H30N2O6, CAS 2172087-53-3](/s/FGNVZFBXVIUJOP-UHFFFAOYSA-N.svg)
3-(2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}ethoxy)propanoic acid
CAS 2172087-53-3C26H30N2O6
![2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-methoxy-2-methylpropanoic acid chemical structure, C26H30N2O6, CAS 2171967-05-6](/s/FXARYDZSVXEMEI-UHFFFAOYSA-N.svg)
2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-methoxy-2-methylpropanoic acid
CAS 2171967-05-6C26H30N2O6
![4-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-methoxybutanoic acid chemical structure, C26H30N2O6, CAS 2172545-97-8](/s/JGGJSCXCKBFQFT-UHFFFAOYSA-N.svg)
4-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-methoxybutanoic acid
CAS 2172545-97-8C26H30N2O6
![2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4,4-difluorobutanoic acid chemical structure, C25H26F2N2O5, CAS 2171648-90-9](/s/WVDFIBGDERUZSS-UHFFFAOYSA-N.svg)
2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4,4-difluorobutanoic acid
CAS 2171648-90-9C25H26F2N2O5
![(2S)-3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-hydroxypropanoic acid chemical structure, C24H26N2O6, CAS 2171156-62-8](/s/KRCHMPFTDBDFKL-XFMWISLNSA-N.svg)
(2S)-3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-hydroxypropanoic acid
CAS 2171156-62-8C24H26N2O6
![2-Ethyl-2-({2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}methyl)butanoic acid chemical structure, C28H34N2O5, CAS 2172575-01-6](/s/PBPWDCMEZUOHKZ-UHFFFAOYSA-N.svg)
2-Ethyl-2-({2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}methyl)butanoic acid
CAS 2172575-01-6C28H34N2O5
![3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-methoxypropanoic acid chemical structure, C25H28N2O6, CAS 2171938-86-4](/s/NYWAMZAYDHGPIP-UHFFFAOYSA-N.svg)
3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-methoxypropanoic acid
CAS 2171938-86-4C25H28N2O6
![4-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-hydroxybutanoic acid chemical structure, C25H28N2O6, CAS 2172167-29-0](/s/LNCNINPBIFVFEG-UHFFFAOYSA-N.svg)
4-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-hydroxybutanoic acid
CAS 2172167-29-0C25H28N2O6
![(2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4-hydroxybutanoic acid chemical structure, C25H28N2O6, CAS 2171288-57-4](/s/RHCXMQFVACWFMG-LGHDPPOTSA-N.svg)
(2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4-hydroxybutanoic acid
CAS 2171288-57-4C25H28N2O6
![(2R)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4-hydroxybutanoic acid chemical structure, C25H28N2O6, CAS 2171200-33-0](/s/RHCXMQFVACWFMG-WTOQYCPUSA-N.svg)
(2R)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4-hydroxybutanoic acid
CAS 2171200-33-0C25H28N2O6
- (2S)-3-(tert-Butoxy)-2-{[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}propanoic acid2171282-01-0C27H32N2O6
- 2-{1-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-methylformamido}-4,4-dimethylpentanoic acid2171551-46-3C28H34N2O5
- 2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-propylacetamido}acetic acid2172004-92-9C26H30N2O5
- 2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-methylacetamido}butanoic acid2171722-35-1C26H30N2O5
- 3-{N-Ethyl-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}propanoic acid2171866-31-0C26H30N2O5
- 3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-methylbutanoic acid2172059-52-6C26H30N2O5
- 4-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-methylbutanoic acid2172005-04-6C26H30N2O5
- 4-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-methylbutanoic acid2172574-07-9C26H30N2O5
- 3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}pentanoic acid2172249-63-5C26H30N2O5
- (2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}pentanoic acid2171275-00-4C26H30N2O5
- 5-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-methylpentanoic acid2171867-09-5C27H32N2O5
- 2-[N-(2,2-Dimethylpropyl)-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido]acetic acid2171867-19-7C28H34N2O5
- 4-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-methoxybutanoic acid2172033-40-6C26H30N2O6
- 2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-(prop-2-yn-1-yl)acetamido}acetic acid2171934-31-7C26H26N2O5
- 2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}pent-4-ynoic acid2171547-79-6C26H26N2O5
- (2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-methylacetamido}propanoic acid2171158-96-4C25H28N2O5
- 4-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}but-2-ynoic acid2172282-19-6C25H24N2O5
- (3R)-3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}butanoic acid2171159-02-5C25H28N2O5
- 5-{1-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-methylformamido}pentanoic acid2172437-37-3C26H30N2O5
- 5-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-methylacetamido}pentanoic acid2172163-15-2C27H32N2O5
- 2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3,3,3-trifluoro-2-methylpropanoic acid2172034-50-1C25H25F3N2O5
- 2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-(2,2,2-trifluoroethyl)acetamido}acetic acid2172548-12-6C25H25F3N2O5
- 2-{N-[2-(Dimethylamino)ethyl]-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}acetic acid2172287-57-7C27H33N3O5
- 3-(Dimethylamino)-2-{2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}propanoic acid2171605-30-2C26H31N3O5
Related scaffolds
Same ring framework with different atoms or bond orders
