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Murcko scaffold

Ring system with 4 rings and 22 atoms

840 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
840
With full pages
15
Scaffold SMILES

O=C(NC1CCC1)OCC1c2ccccc2-c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC1CCC1)OCC1c2ccccc2-c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 673 to 720 of 840 chemicals

4-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}butanoic acid chemical structure, C24H26N2O5, CAS 2171839-05-5
4-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}butanoic acid
CAS 2171839-05-5C24H26N2O5
5-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-3-methylpentanoic acid chemical structure, C26H30N2O5, CAS 2172207-95-1
5-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-3-methylpentanoic acid
CAS 2172207-95-1C26H30N2O5
(2S)-2-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}butanoic acid chemical structure, C24H26N2O5, CAS 2171232-74-7
(2S)-2-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}butanoic acid
CAS 2171232-74-7C24H26N2O5
2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-(2-methoxyethyl)acetamido}acetic acid chemical structure, C26H30N2O6, CAS 2172118-62-4
2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-(2-methoxyethyl)acetamido}acetic acid
CAS 2172118-62-4C26H30N2O6
(2S)-3-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-hydroxypropanoic acid chemical structure, C24H26N2O6, CAS 2171158-50-0
(2S)-3-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-hydroxypropanoic acid
CAS 2171158-50-0C24H26N2O6
(3R)-3-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}butanoic acid chemical structure, C24H26N2O5, CAS 2171164-34-2
(3R)-3-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}butanoic acid
CAS 2171164-34-2C24H26N2O5
(2R)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4-(methylsulfanyl)butanoic acid chemical structure, C26H30N2O5S, CAS 2171270-17-8
(2R)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4-(methylsulfanyl)butanoic acid
CAS 2171270-17-8C26H30N2O5S
(3R)-3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}hexanoic acid chemical structure, C27H32N2O5, CAS 2171198-32-4
(3R)-3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}hexanoic acid
CAS 2171198-32-4C27H32N2O5
4-(Dimethylamino)-2-{2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}butanoic acid chemical structure, C27H33N3O5, CAS 2171595-95-0
4-(Dimethylamino)-2-{2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}butanoic acid
CAS 2171595-95-0C27H33N3O5
2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-methylacetamido}acetic acid chemical structure, C24H26N2O5, CAS 2172209-73-1
2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-methylacetamido}acetic acid
CAS 2172209-73-1C24H26N2O5
(2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}propanoic acid chemical structure, C24H26N2O5, CAS 2171175-12-3
(2S)-2-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}propanoic acid
CAS 2171175-12-3C24H26N2O5
4-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-methylbutanoic acid chemical structure, C26H30N2O5, CAS 2172008-00-1
4-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-3-methylbutanoic acid
CAS 2172008-00-1C26H30N2O5
2-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}butanoic acid chemical structure, C24H26N2O5, CAS 2171602-76-7
2-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}butanoic acid
CAS 2171602-76-7C24H26N2O5
(2R)-2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4-hydroxybutanoic acid chemical structure, C25H28N2O6, CAS 2171256-21-4
(2R)-2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-4-hydroxybutanoic acid
CAS 2171256-21-4C25H28N2O6
2-({[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}oxy)propanoic acid chemical structure, C23H24N2O6, CAS 2171834-69-6
2-({[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}oxy)propanoic acid
CAS 2171834-69-6C23H24N2O6
3-{N-Ethyl-2-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}propanoic acid chemical structure, C26H30N2O5, CAS 2172278-33-8
3-{N-Ethyl-2-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}propanoic acid
CAS 2172278-33-8C26H30N2O5
2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-(propan-2-yl)acetamido}acetic acid chemical structure, C26H30N2O5, CAS 2172156-98-6
2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-(propan-2-yl)acetamido}acetic acid
CAS 2172156-98-6C26H30N2O5
3-({[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}methyl)pentanoic acid chemical structure, C26H30N2O5, CAS 2171998-11-9
3-({[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}methyl)pentanoic acid
CAS 2171998-11-9C26H30N2O5
4-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-hydroxybutanoic acid chemical structure, C25H28N2O6, CAS 2172274-75-6
4-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-hydroxybutanoic acid
CAS 2172274-75-6C25H28N2O6
(2S)-2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}hexanoic acid chemical structure, C27H32N2O5, CAS 2171222-46-9
(2S)-2-{2-[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}hexanoic acid
CAS 2171222-46-9C27H32N2O5
(2R)-2-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}pentanoic acid chemical structure, C25H28N2O5, CAS 2171207-19-3
(2R)-2-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}pentanoic acid
CAS 2171207-19-3C25H28N2O5
3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-(propan-2-yl)butanoic acid chemical structure, C28H34N2O5, CAS 2172246-05-6
3-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]acetamido}-2-(propan-2-yl)butanoic acid
CAS 2172246-05-6C28H34N2O5
(3R)-3-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-4-methylpentanoic acid chemical structure, C26H30N2O5, CAS 2171244-01-0
(3R)-3-{[1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}-4-methylpentanoic acid
CAS 2171244-01-0C26H30N2O5
5-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-methylacetamido}pentanoic acid chemical structure, C27H32N2O5, CAS 2172265-34-6
5-{2-[3-({[(9H-Fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]-N-methylacetamido}pentanoic acid
CAS 2172265-34-6C27H32N2O5