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Murcko scaffold

Ring system with 2 rings and 10 atoms

135 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
135
With full pages
5
Scaffold SMILES

c1cncc(N2CCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cncc(N2CCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 135 chemicals

tert-Butyl 1-(6-chloro-3-pyridinyl)-3-azetidinylcarbamate chemical structure, C13H18ClN3O2, CAS 309962-73-0
tert-Butyl 1-(6-chloro-3-pyridinyl)-3-azetidinylcarbamate
CAS 309962-73-0C13H18ClN3O2
5-(Azetidin-1-yl)pyridin-2-amine chemical structure, C8H11N3, CAS 1240618-19-2
5-(Azetidin-1-yl)pyridin-2-amine
CAS 1240618-19-2C8H11N3
3-Methyl-1-(6-nitropyridin-3-yl)azetidin-3-ol chemical structure, C9H11N3O3, CAS 1346674-89-2
3-Methyl-1-(6-nitropyridin-3-yl)azetidin-3-ol
CAS 1346674-89-2C9H11N3O3
1-(6-Aminopyridin-3-yl)azetidin-3-ol chemical structure, C8H11N3O, CAS 1253911-54-4
1-(6-Aminopyridin-3-yl)azetidin-3-ol
CAS 1253911-54-4C8H11N3O
5-(3-Methylazetidin-1-yl)pyridin-2-amine chemical structure, C9H13N3, CAS 1346675-40-8
5-(3-Methylazetidin-1-yl)pyridin-2-amine
CAS 1346675-40-8C9H13N3
1-(6-Aminopyridin-3-yl)-3-methylazetidin-3-ol chemical structure, C9H13N3O, CAS 1253911-28-2
1-(6-Aminopyridin-3-yl)-3-methylazetidin-3-ol
CAS 1253911-28-2C9H13N3O
5-[3-(tert-Butyl-dimethyl-silanyloxy)-azetidin-1-yl]-pyridin-2-ylamine chemical structure, C14H25N3OSi, CAS 1211443-68-3
5-[3-(tert-Butyl-dimethyl-silanyloxy)-azetidin-1-yl]-pyridin-2-ylamine
CAS 1211443-68-3C14H25N3OSi
5-[3-(tert-Butyl-dimethyl-silanyloxy)-azetidin-1-yl]-2-nitro-pyridine chemical structure, C14H23N3O3Si, CAS 1211443-65-0
5-[3-(tert-Butyl-dimethyl-silanyloxy)-azetidin-1-yl]-2-nitro-pyridine
CAS 1211443-65-0C14H23N3O3Si
1-(6-Nitro-pyridin-3-yl)-azetidin-3-ol chemical structure, C8H9N3O3, CAS 1211443-63-8
1-(6-Nitro-pyridin-3-yl)-azetidin-3-ol
CAS 1211443-63-8C8H9N3O3
3-(1-Azetidinyl)-5-bromopyridine chemical structure, C8H9BrN2, CAS 1257431-55-2
3-(1-Azetidinyl)-5-bromopyridine
CAS 1257431-55-2C8H9BrN2
5-(Azetidin-1-yl)-2-nitropyridine chemical structure, C8H9N3O2, CAS 1862803-39-1
5-(Azetidin-1-yl)-2-nitropyridine
CAS 1862803-39-1C8H9N3O2
1-(Pyridin-3-yl)azetidin-3-ol chemical structure, C8H10N2O, CAS 1823946-64-0
1-(Pyridin-3-yl)azetidin-3-ol
CAS 1823946-64-0C8H10N2O
Methyl 5-(3-hydroxyazetidin-1-yl)nicotinate chemical structure, C10H12N2O3, CAS 1418274-46-0
Methyl 5-(3-hydroxyazetidin-1-yl)nicotinate
CAS 1418274-46-0C10H12N2O3
5-(3-Methylazetidin-1-yl)pyridine-3-carboxylic acid chemical structure, C10H12N2O2, CAS 1518440-05-5
5-(3-Methylazetidin-1-yl)pyridine-3-carboxylic acid
CAS 1518440-05-5C10H12N2O2
5-(3-Methoxyazetidin-1-yl)-2-nitropyridine chemical structure, C9H11N3O3, CAS 1434053-96-9
5-(3-Methoxyazetidin-1-yl)-2-nitropyridine
CAS 1434053-96-9C9H11N3O3
5-(3-Methoxyazetidin-1-yl)pyridin-2-amine chemical structure, C9H13N3O, CAS 1434053-97-0
5-(3-Methoxyazetidin-1-yl)pyridin-2-amine
CAS 1434053-97-0C9H13N3O
3-(3,3-Difluoroazetidin-1-yl)-5-fluoropyridine chemical structure, C8H7F3N2, CAS 1707580-98-0
3-(3,3-Difluoroazetidin-1-yl)-5-fluoropyridine
CAS 1707580-98-0C8H7F3N2
3-Bromo-5-(3,3-difluoroazetidin-1-yl)pyridine chemical structure, C8H7BrF2N2, CAS 1779133-56-0
3-Bromo-5-(3,3-difluoroazetidin-1-yl)pyridine
CAS 1779133-56-0C8H7BrF2N2
4-Bromo-3-(3,3-difluoroazetidin-1-yl)pyridine chemical structure, C8H7BrF2N2, CAS 1779133-61-7
4-Bromo-3-(3,3-difluoroazetidin-1-yl)pyridine
CAS 1779133-61-7C8H7BrF2N2
2-Bromo-3-(3,3-difluoroazetidin-1-yl)pyridine chemical structure, C8H7BrF2N2, CAS 1707391-25-0
2-Bromo-3-(3,3-difluoroazetidin-1-yl)pyridine
CAS 1707391-25-0C8H7BrF2N2
2-Bromo-5-(3,3-difluoroazetidin-1-yl)pyridine chemical structure, C8H7BrF2N2, CAS 1779121-51-5
2-Bromo-5-(3,3-difluoroazetidin-1-yl)pyridine
CAS 1779121-51-5C8H7BrF2N2
3-(3,3-Difluoroazetidin-1-yl)isonicotinaldehyde chemical structure, C9H8F2N2O, CAS 1774895-44-1
3-(3,3-Difluoroazetidin-1-yl)isonicotinaldehyde
CAS 1774895-44-1C9H8F2N2O
5-(3,3-Difluoroazetidin-1-yl)nicotinaldehyde chemical structure, C9H8F2N2O, CAS 1774895-47-4
5-(3,3-Difluoroazetidin-1-yl)nicotinaldehyde
CAS 1774895-47-4C9H8F2N2O
3-(3,3-Difluoroazetidin-1-yl)picolinaldehyde chemical structure, C9H8F2N2O, CAS 1774895-80-5
3-(3,3-Difluoroazetidin-1-yl)picolinaldehyde
CAS 1774895-80-5C9H8F2N2O