CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 19 atoms

61 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
61
With full pages
13
Scaffold SMILES

O=c1[nH]c2ccccc2cc1CNc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c2ccccc2cc1CNc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 61 chemicals

3-[(4-Methoxyanilino)methyl]-1H-quinolin-2-one chemical structure, C17H16N2O2, CAS 585550-76-1
3-[(4-Methoxyanilino)methyl]-1H-quinolin-2-one
CAS 585550-76-1C17H16N2O2
N-(4-Ethoxyphenyl)-N-[(2-hydroxy-6-methoxyquinolin-3-yl)methyl]methanesulfonamide chemical structure, C20H22N2O5S, CAS 879439-45-9
N-(4-Ethoxyphenyl)-N-[(2-hydroxy-6-methoxyquinolin-3-yl)methyl]methanesulfonamide
CAS 879439-45-9C20H22N2O5S
N-[(2-Oxo-1H-quinolin-3-yl)methyl]-N-phenylacetamide chemical structure, C18H16N2O2, CAS 488108-22-1
N-[(2-Oxo-1H-quinolin-3-yl)methyl]-N-phenylacetamide
CAS 488108-22-1C18H16N2O2
N-(2-Methylphenyl)-N-[(2-oxo-1H-quinolin-3-yl)methyl]acetamide chemical structure, C19H18N2O2, CAS 489399-76-0
N-(2-Methylphenyl)-N-[(2-oxo-1H-quinolin-3-yl)methyl]acetamide
CAS 489399-76-0C19H18N2O2
N-(2-Hydroxy-quinolin-3-ylmethyl)-N-p-tolyl-acetamide chemical structure, C19H18N2O2, CAS 488840-51-3
N-(2-Hydroxy-quinolin-3-ylmethyl)-N-p-tolyl-acetamide
CAS 488840-51-3C19H18N2O2
N-(4-Methoxyphenyl)-N-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]acetamide chemical structure, C20H20N2O3, CAS 510738-88-2
N-(4-Methoxyphenyl)-N-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]acetamide
CAS 510738-88-2C20H20N2O3
N-(2-Hydroxy-6-methyl-quinolin-3-ylmethyl)-N-(4-methoxy-phenyl)-acetamide chemical structure, C20H20N2O3, CAS 510739-02-3
N-(2-Hydroxy-6-methyl-quinolin-3-ylmethyl)-N-(4-methoxy-phenyl)-acetamide
CAS 510739-02-3C20H20N2O3
N-(3,4-Dimethylphenyl)-N-[(2-oxo-1H-quinolin-3-yl)methyl]butanamide chemical structure, C22H24N2O2, CAS 500271-42-1
N-(3,4-Dimethylphenyl)-N-[(2-oxo-1H-quinolin-3-yl)methyl]butanamide
CAS 500271-42-1C22H24N2O2
2-Methyl-N-[(2-oxo-1,2-dihydroquinolin-3-yl)methyl]-N-phenylpropanamide chemical structure, C20H20N2O2, CAS 667881-45-0
2-Methyl-N-[(2-oxo-1,2-dihydroquinolin-3-yl)methyl]-N-phenylpropanamide
CAS 667881-45-0C20H20N2O2
7-Methoxy-3-{[(4-methylphenyl)amino]methyl}-1,2-dihydroquinolin-2-one chemical structure, C18H18N2O2, CAS 483290-96-6
7-Methoxy-3-{[(4-methylphenyl)amino]methyl}-1,2-dihydroquinolin-2-one
CAS 483290-96-6C18H18N2O2
7-Methoxy-3-{[(4-methoxyphenyl)amino]methyl}quinolin-2(1H)-one chemical structure, C18H18N2O3, CAS 335222-91-8
7-Methoxy-3-{[(4-methoxyphenyl)amino]methyl}quinolin-2(1H)-one
CAS 335222-91-8C18H18N2O3
3-[(2-Chloro-phenylamino)-methyl]-7-methoxy-1H-quinolin-2-one chemical structure, C17H15ClN2O2, CAS 483291-05-0
3-[(2-Chloro-phenylamino)-methyl]-7-methoxy-1H-quinolin-2-one
CAS 483291-05-0C17H15ClN2O2
3-[[(2,4-Dimethoxyphenyl)amino]methyl]-6-methyl-2(1H)-quinolinone chemical structure, C19H20N2O3, CAS 483286-59-5
3-[[(2,4-Dimethoxyphenyl)amino]methyl]-6-methyl-2(1H)-quinolinone
CAS 483286-59-5C19H20N2O3
N-(3,4-Dimethylphenyl)-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]propanamide chemical structure, C22H24N2O2, CAS 673441-16-2
N-(3,4-Dimethylphenyl)-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]propanamide
CAS 673441-16-2C22H24N2O2
N-(2,4-Dimethylphenyl)-N-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]acetamide chemical structure, C21H22N2O2, CAS 672266-84-1
N-(2,4-Dimethylphenyl)-N-[(8-methyl-2-oxo-1H-quinolin-3-yl)methyl]acetamide
CAS 672266-84-1C21H22N2O2
N-(3-Methylphenyl)-N-[(2-oxo-1H-quinolin-3-yl)methyl]acetamide chemical structure, C19H18N2O2, CAS 500267-97-0
N-(3-Methylphenyl)-N-[(2-oxo-1H-quinolin-3-yl)methyl]acetamide
CAS 500267-97-0C19H18N2O2
N-[(8-Methyl-2-oxo-1H-quinolin-3-yl)methyl]-N-(2-methylphenyl)butanamide chemical structure, C22H24N2O2, CAS 672277-27-9
N-[(8-Methyl-2-oxo-1H-quinolin-3-yl)methyl]-N-(2-methylphenyl)butanamide
CAS 672277-27-9C22H24N2O2
N-(2,5-Dimethylphenyl)-N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]propanamide chemical structure, C22H24N2O2, CAS 671769-98-5
N-(2,5-Dimethylphenyl)-N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]propanamide
CAS 671769-98-5C22H24N2O2
N-(3-Methylphenyl)-N-[(2-oxo-1H-quinolin-3-yl)methyl]propanamide chemical structure, C20H20N2O2, CAS 489462-68-2
N-(3-Methylphenyl)-N-[(2-oxo-1H-quinolin-3-yl)methyl]propanamide
CAS 489462-68-2C20H20N2O2
N-(2-Methoxyphenyl)-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]acetamide chemical structure, C20H20N2O3, CAS 672280-98-7
N-(2-Methoxyphenyl)-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]acetamide
CAS 672280-98-7C20H20N2O3
N-(3,4-Dimethylphenyl)-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]acetamide chemical structure, C21H22N2O2, CAS 671762-08-6
N-(3,4-Dimethylphenyl)-N-[(6-methyl-2-oxo-1H-quinolin-3-yl)methyl]acetamide
CAS 671762-08-6C21H22N2O2
N-(2,4-Dimethylphenyl)-N-[(2-oxo-1H-quinolin-3-yl)methyl]propanamide chemical structure, C21H22N2O2, CAS 488110-86-7
N-(2,4-Dimethylphenyl)-N-[(2-oxo-1H-quinolin-3-yl)methyl]propanamide
CAS 488110-86-7C21H22N2O2
N-(2,4-Dimethylphenyl)-N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]acetamide chemical structure, C21H22N2O2, CAS 672894-14-3
N-(2,4-Dimethylphenyl)-N-[(7-methyl-2-oxo-1H-quinolin-3-yl)methyl]acetamide
CAS 672894-14-3C21H22N2O2
7-Methyl-3-{[(4-methylphenyl)amino]methyl}quinolin-2(1H)-one chemical structure, C18H18N2O, CAS 673443-60-2
7-Methyl-3-{[(4-methylphenyl)amino]methyl}quinolin-2(1H)-one
CAS 673443-60-2C18H18N2O