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Murcko scaffold

Ring system with 3 rings and 18 atoms

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
21
With full pages
5
Scaffold SMILES

O=c1[nH]cccc1NCc1nc2ccccc2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]cccc1NCc1nc2ccccc2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

2(1H)-Pyridinone, 3-(((4,7-dimethyl-2-benzoxazolyl)methyl)amino)-5-ethyl-6-methyl- chemical structure, C18H21N3O2, CAS 135525-77-8
2(1H)-Pyridinone, 3-(((4,7-dimethyl-2-benzoxazolyl)methyl)amino)-5-ethyl-6-methyl-
CAS 135525-77-8C18H21N3O2
2(1H)-Pyridinone, 3-(((4,7-dichloro-2-benzoxazolyl)methyl)amino)-5-ethyl-6-methyl- chemical structure, C16H15Cl2N3O2, CAS 135525-78-9
2(1H)-Pyridinone, 3-(((4,7-dichloro-2-benzoxazolyl)methyl)amino)-5-ethyl-6-methyl-
CAS 135525-78-9C16H15Cl2N3O2
2(1H)-Pyridinone, 3-((2-benzoxazolylmethyl)amino)-5-ethyl-6-methyl- chemical structure, C16H17N3O2, CAS 135525-70-1
2(1H)-Pyridinone, 3-((2-benzoxazolylmethyl)amino)-5-ethyl-6-methyl-
CAS 135525-70-1C16H17N3O2
3-((4-Methylbenzoxazol-2-ylmethyl)amino)-5-ethyl-6-methlpyridin-2(1H)-one chemical structure, C17H19N3O2, CAS 135525-75-6
3-((4-Methylbenzoxazol-2-ylmethyl)amino)-5-ethyl-6-methlpyridin-2(1H)-one
CAS 135525-75-6C17H19N3O2
3-((7-Methyl-Benzoxazol-2-ylmethyl)amino)-5-ethyl-6-methlpyridin-2(1H)-one chemical structure, C17H19N3O2, CAS 135525-76-7
3-((7-Methyl-Benzoxazol-2-ylmethyl)amino)-5-ethyl-6-methlpyridin-2(1H)-one
CAS 135525-76-7C17H19N3O2
2(1H)-Pyridinone, 5-ethyl-6-methyl-3-(((5-methyl-2-benzoxazolyl)methyl)amino)- chemical structure, C17H19N3O2, CAS 143708-02-5
2(1H)-Pyridinone, 5-ethyl-6-methyl-3-(((5-methyl-2-benzoxazolyl)methyl)amino)-
CAS 143708-02-5C17H19N3O2
3-((6-Methyl-benzoxazol-2-ylmethyl)amino)-5-ethyl-6-methylpyridin-2(1H)-one chemical structure, C17H19N3O2, CAS 143708-03-6
3-((6-Methyl-benzoxazol-2-ylmethyl)amino)-5-ethyl-6-methylpyridin-2(1H)-one
CAS 143708-03-6C17H19N3O2
2(1H)-Pyridinone, 5-ethyl-3-(((7-ethyl-2-benzoxazolyl)methyl)amino)-6-methyl- chemical structure, C18H21N3O2, CAS 143708-04-7
2(1H)-Pyridinone, 5-ethyl-3-(((7-ethyl-2-benzoxazolyl)methyl)amino)-6-methyl-
CAS 143708-04-7C18H21N3O2
2(1H)-Pyridinone, 3-(((4-chloro-2-benzoxazolyl)methyl)amino)-5-ethyl-6-methyl- chemical structure, C16H16ClN3O2, CAS 139548-50-8
2(1H)-Pyridinone, 3-(((4-chloro-2-benzoxazolyl)methyl)amino)-5-ethyl-6-methyl-
CAS 139548-50-8C16H16ClN3O2
2(1H)-Pyridinone, 3-(((7-chloro-2-benzoxazolyl)methyl)amino)-5-ethyl-6-methyl- chemical structure, C16H16ClN3O2, CAS 139548-35-9
2(1H)-Pyridinone, 3-(((7-chloro-2-benzoxazolyl)methyl)amino)-5-ethyl-6-methyl-
CAS 139548-35-9C16H16ClN3O2
2(1H)-Pyridinone, 5-ethyl-3-(((4-fluoro-2-benzoxazolyl)methyl)amino)-6-methyl- chemical structure, C16H16FN3O2, CAS 139571-98-5
2(1H)-Pyridinone, 5-ethyl-3-(((4-fluoro-2-benzoxazolyl)methyl)amino)-6-methyl-
CAS 139571-98-5C16H16FN3O2
2(1H)-Pyridinone, 5-ethyl-3-(((5-fluoro-2-benzoxazolyl)methyl)amino)-6-methyl- chemical structure, C16H16FN3O2, CAS 143708-05-8
2(1H)-Pyridinone, 5-ethyl-3-(((5-fluoro-2-benzoxazolyl)methyl)amino)-6-methyl-
CAS 143708-05-8C16H16FN3O2
2(1H)-Pyridinone, 5-ethyl-3-(((6-fluoro-2-benzoxazolyl)methyl)amino)-6-methyl- chemical structure, C16H16FN3O2, CAS 143708-06-9
2(1H)-Pyridinone, 5-ethyl-3-(((6-fluoro-2-benzoxazolyl)methyl)amino)-6-methyl-
CAS 143708-06-9C16H16FN3O2
2(1H)-Pyridinone, 5-ethyl-3-(((7-fluoro-2-benzoxazolyl)methyl)amino)-6-methyl- chemical structure, C16H16FN3O2, CAS 139548-49-5
2(1H)-Pyridinone, 5-ethyl-3-(((7-fluoro-2-benzoxazolyl)methyl)amino)-6-methyl-
CAS 139548-49-5C16H16FN3O2
3-{[(4,7-Dichloro-1,3-benzoxazol-2-yl)methyl](methyl)amino}-5-ethyl-6-methyl-1,2-dihydropyridin-2-one chemical structure, C17H17Cl2N3O2, CAS 139548-05-3
3-{[(4,7-Dichloro-1,3-benzoxazol-2-yl)methyl](methyl)amino}-5-ethyl-6-methyl-1,2-dihydropyridin-2-one
CAS 139548-05-3C17H17Cl2N3O2
3-{[(4,7-Dimethyl-1,3-benzoxazol-2-yl)methyl](methyl)amino}-5-ethyl-6-methyl-1,2-dihydropyridin-2-one chemical structure, C19H23N3O2, CAS 139548-06-4
3-{[(4,7-Dimethyl-1,3-benzoxazol-2-yl)methyl](methyl)amino}-5-ethyl-6-methyl-1,2-dihydropyridin-2-one
CAS 139548-06-4C19H23N3O2
3-[(4,7-Dichloro-1,3-benzoxazol-2-yl)methylamino]-4,6-dimethyl-1H-pyridin-2-one chemical structure, C15H13Cl2N3O2, CAS 143708-16-1
3-[(4,7-Dichloro-1,3-benzoxazol-2-yl)methylamino]-4,6-dimethyl-1H-pyridin-2-one
CAS 143708-16-1C15H13Cl2N3O2
3-(1,3-Benzoxazol-2-ylmethylamino)-5-ethyl-4,6-dimethyl-1H-pyridin-2-one chemical structure, C17H19N3O2, CAS 139548-38-2
3-(1,3-Benzoxazol-2-ylmethylamino)-5-ethyl-4,6-dimethyl-1H-pyridin-2-one
CAS 139548-38-2C17H19N3O2
3-(1,3-Benzoxazol-2-ylmethylamino)-6-methyl-5-methylsulfonyl-1H-pyridin-2-one chemical structure, C15H15N3O4S, CAS 143708-17-2
3-(1,3-Benzoxazol-2-ylmethylamino)-6-methyl-5-methylsulfonyl-1H-pyridin-2-one
CAS 143708-17-2C15H15N3O4S
Ethyl 5-(1,3-benzoxazol-2-ylmethylamino)-2-methyl-6-oxo-1H-pyridine-3-carboxylate chemical structure, C17H17N3O4, CAS 143708-18-3
Ethyl 5-(1,3-benzoxazol-2-ylmethylamino)-2-methyl-6-oxo-1H-pyridine-3-carboxylate
CAS 143708-18-3C17H17N3O4
3-(1,3-Benzoxazol-2-ylmethylamino)-6-methyl-5-methylsulfinyl-1H-pyridin-2-one chemical structure, C15H15N3O3S, CAS 143708-19-4
3-(1,3-Benzoxazol-2-ylmethylamino)-6-methyl-5-methylsulfinyl-1H-pyridin-2-one
CAS 143708-19-4C15H15N3O3S